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Jesse I. Mobbs
Jesse I. Mobbs
Verified email at monash.edu
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Year
Structural and regulatory diversity shape HLA-C protein expression levels
G Kaur, S Gras, JI Mobbs, JP Vivian, A Cortes, T Barber, SB Kuttikkatte, ...
Nature communications 8 (1), 15924, 2017
1062017
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity
JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ...
PLoS biology 19 (6), e3001295, 2021
492021
The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C* 06: 02 molecule
JI Mobbs, PT Illing, NL Dudek, AG Brooks, DG Baker, AW Purcell, ...
Journal of Biological Chemistry 292 (42), 17203-17215, 2017
422017
Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase
JI Mobbs, A Koay, A Di Paolo, M Bieri, EJ Petrie, MA Gorman, L Doughty, ...
Biochemical Journal 468 (2), 245-257, 2015
302015
AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding
M Bieri, JI Mobbs, A Koay, G Louey, YF Mok, DM Hatters, JT Park, ...
Biophysical journal 102 (2), 305-314, 2012
272012
The P2X1 receptor as a therapeutic target
FM Bennetts, JI Mobbs, S Ventura, DM Thal
Purinergic signalling 18 (4), 421-433, 2022
132022
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
Z Vuckovic, J Wang, V Pham, JI Mobbs, MJ Belousoff, A Bhattarai, ...
Elife 12, e83477, 2023
92023
Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors
JI Mobbs, KA Black, M Tran, WAC Burger, H Venugopal, TR Holman, ...
Blood 142 (14), 1233-1242, 2023
72023
The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors
L Zhang, JI Mobbs, LT May, A Glukhova, DM Thal
Current Opinion in Structural Biology 79, 102560, 2023
42023
Unravelling the Carbohydrate‐Binding Preferences of the Carbohydrate‐Binding Modules of AMP‐Activated Protein Kinase
JI Mobbs, A Di Paolo, RD Metcalfe, E Selig, DI Stapleton, MDW Griffin, ...
Chembiochem 19 (3), 229-238, 2018
42018
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR
WAC Burger, V Pham, Z Vuckovic, AS Powers, JI Mobbs, Y Laloudakis, ...
Nature communications 14 (1), 5440, 2023
32023
Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK β-Subunit Carbohydrate-Binding Modules
PR Gooley, A Koay, JI Mobbs
AMPK: Methods and Protocols, 87-98, 2018
22018
Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗ 06: 02
S Anand, DR Littler, JI Mobbs, A Braun, DG Baker, L Tennant, AW Purcell, ...
Journal of Biological Chemistry 299 (7), 2023
12023
Structural insights into the human P2X1 receptor and ligand interactions
F Bennetts, H Venugopal, A Glukhova, JI Mobbs, S Ventura, DM Thal
bioRxiv, 2024.04. 04.588192, 2024
2024
013 Uncovering antigen triggers in genetically predisposed psoriasis patients
A Braun, J Ye, J Mobbs, S Anand, J Tuomisto, S Chung, E Hughes, H Oo, ...
Journal of Investigative Dermatology 143 (5), S3, 2023
2023
The Clinical Candidate Xanomeline Displays a Dual Orthosteric and Allosteric Binding Profile at the M4 mAChR
WAC Burger, V Pham, A Powers, Z Vuckovic, JI Mobbs, A Glukhova, ...
NEUROPSYCHOPHARMACOLOGY 47 (SUPPL 1), 339-340, 2022
2022
Milestones to a cure: a path to uncovering HLA-C* 06: 02 restricted antigen triggers in psoriasis
A Braun, J Mobbs, S Anand, J Tuomisto, SZ Chung, E Hughes, ...
EUROPEAN JOURNAL OF IMMUNOLOGY 52, 152-153, 2022
2022
Molecular Characterisation of the Carbohydrate Binding Modules of AMPK
J Mobbs
University of Melbourne, Department of Biochemistry and Molecular Biology, 2016
2016
This is an Open Access document downloaded from ORCA, Cardiff University's institutional repository: http://orca. cf. ac. uk/102240/This is the author’s version of a work that …
G Kaur, S Gras, JI Mobbs, JP Vivian, A Cortes, T Barber, SB Kuttikkatte, ...
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins: insight into mechanisms of G protein selectivity
J Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ...
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Articles 1–20