Structural and regulatory diversity shape HLA-C protein expression levels G Kaur, S Gras, JI Mobbs, JP Vivian, A Cortes, T Barber, SB Kuttikkatte, ... Nature communications 8 (1), 15924, 2017 | 106 | 2017 |
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... PLoS biology 19 (6), e3001295, 2021 | 49 | 2021 |
The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C* 06: 02 molecule JI Mobbs, PT Illing, NL Dudek, AG Brooks, DG Baker, AW Purcell, ... Journal of Biological Chemistry 292 (42), 17203-17215, 2017 | 42 | 2017 |
Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase JI Mobbs, A Koay, A Di Paolo, M Bieri, EJ Petrie, MA Gorman, L Doughty, ... Biochemical Journal 468 (2), 245-257, 2015 | 30 | 2015 |
AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding M Bieri, JI Mobbs, A Koay, G Louey, YF Mok, DM Hatters, JT Park, ... Biophysical journal 102 (2), 305-314, 2012 | 27 | 2012 |
The P2X1 receptor as a therapeutic target FM Bennetts, JI Mobbs, S Ventura, DM Thal Purinergic signalling 18 (4), 421-433, 2022 | 13 | 2022 |
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics Z Vuckovic, J Wang, V Pham, JI Mobbs, MJ Belousoff, A Bhattarai, ... Elife 12, e83477, 2023 | 9 | 2023 |
Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors JI Mobbs, KA Black, M Tran, WAC Burger, H Venugopal, TR Holman, ... Blood 142 (14), 1233-1242, 2023 | 7 | 2023 |
The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors L Zhang, JI Mobbs, LT May, A Glukhova, DM Thal Current Opinion in Structural Biology 79, 102560, 2023 | 4 | 2023 |
Unravelling the Carbohydrate‐Binding Preferences of the Carbohydrate‐Binding Modules of AMP‐Activated Protein Kinase JI Mobbs, A Di Paolo, RD Metcalfe, E Selig, DI Stapleton, MDW Griffin, ... Chembiochem 19 (3), 229-238, 2018 | 4 | 2018 |
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR WAC Burger, V Pham, Z Vuckovic, AS Powers, JI Mobbs, Y Laloudakis, ... Nature communications 14 (1), 5440, 2023 | 3 | 2023 |
Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK β-Subunit Carbohydrate-Binding Modules PR Gooley, A Koay, JI Mobbs AMPK: Methods and Protocols, 87-98, 2018 | 2 | 2018 |
Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗ 06: 02 S Anand, DR Littler, JI Mobbs, A Braun, DG Baker, L Tennant, AW Purcell, ... Journal of Biological Chemistry 299 (7), 2023 | 1 | 2023 |
Structural insights into the human P2X1 receptor and ligand interactions F Bennetts, H Venugopal, A Glukhova, JI Mobbs, S Ventura, DM Thal bioRxiv, 2024.04. 04.588192, 2024 | | 2024 |
013 Uncovering antigen triggers in genetically predisposed psoriasis patients A Braun, J Ye, J Mobbs, S Anand, J Tuomisto, S Chung, E Hughes, H Oo, ... Journal of Investigative Dermatology 143 (5), S3, 2023 | | 2023 |
The Clinical Candidate Xanomeline Displays a Dual Orthosteric and Allosteric Binding Profile at the M4 mAChR WAC Burger, V Pham, A Powers, Z Vuckovic, JI Mobbs, A Glukhova, ... NEUROPSYCHOPHARMACOLOGY 47 (SUPPL 1), 339-340, 2022 | | 2022 |
Milestones to a cure: a path to uncovering HLA-C* 06: 02 restricted antigen triggers in psoriasis A Braun, J Mobbs, S Anand, J Tuomisto, SZ Chung, E Hughes, ... EUROPEAN JOURNAL OF IMMUNOLOGY 52, 152-153, 2022 | | 2022 |
Molecular Characterisation of the Carbohydrate Binding Modules of AMPK J Mobbs University of Melbourne, Department of Biochemistry and Molecular Biology, 2016 | | 2016 |
This is an Open Access document downloaded from ORCA, Cardiff University's institutional repository: http://orca. cf. ac. uk/102240/This is the author’s version of a work that … G Kaur, S Gras, JI Mobbs, JP Vivian, A Cortes, T Barber, SB Kuttikkatte, ... | | |
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins: insight into mechanisms of G protein selectivity J Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... | | |