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Mayank Aggarwal
Mayank Aggarwal
Formulatrix
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Cited by
Year
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo
F Carta, M Aggarwal, A Maresca, A Scozzafava, R McKenna, E Masini, ...
Journal of medicinal chemistry 55 (4), 1721-1730, 2012
2522012
Structural annotation of human carbonic anhydrases
M Aggarwal, CD Boone, B Kondeti, R McKenna
Journal of enzyme inhibition and medicinal chemistry 28 (2), 267-277, 2013
2322013
Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to …
F Pacchiano, M Aggarwal, BS Avvaru, AH Robbins, A Scozzafava, ...
Chemical Communications 46 (44), 8371-8373, 2010
2312010
Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review
M Aggarwal, B Kondeti, R McKenna
Expert opinion on therapeutic patents 23 (6), 717-724, 2013
2022013
Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
F Carta, M Aggarwal, A Maresca, A Scozzafava, R McKenna, CT Supuran
Chemical Communications 48 (13), 1868-1870, 2012
1782012
Insights towards sulfonamide drug specificity in α-carbonic anhydrases
M Aggarwal, B Kondeti, R McKenna
Bioorganic & medicinal chemistry 21 (6), 1526-1533, 2013
1302013
Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding
SZ Fisher, M Aggarwal, AY Kovalevsky, DN Silverman, R McKenna
Journal of the American Chemical Society 134 (36), 14726-14729, 2012
1222012
Update on carbonic anhydrase inhibitors: a patent review (2008–2011)
M Aggarwal, R McKenna
Expert opinion on therapeutic patents 22 (8), 903-915, 2012
1162012
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II …
N Hen, M Bialer, B Yagen, A Maresca, M Aggarwal, AH Robbins, ...
Journal of medicinal chemistry 54 (11), 3977-3981, 2011
872011
Lactate flux in astrocytes is enhanced by a non‐catalytic action of carbonic anhydrase II
MH Stridh, MD Alt, S Wittmann, H Heidtmann, M Aggarwal, B Riederer, ...
The Journal of physiology 590 (10), 2333-2351, 2012
812012
Water networks in fast proton transfer during catalysis by human carbonic anhydrase II
R Mikulski, D West, KH Sippel, BS Avvaru, M Aggarwal, C Tu, R McKenna, ...
Biochemistry 52 (1), 125-131, 2013
662013
Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II
Z Fisher, CD Boone, SM Biswas, B Venkatakrishnan, M Aggarwal, C Tu, ...
Protein Engineering, Design & Selection 25 (7), 347-355, 2012
632012
Carbonic anhydrase inhibition with benzenesulfonamides and tetrafluorobenzenesulfonamides obtained via click chemistry
N Pala, L Micheletto, M Sechi, M Aggarwal, F Carta, R McKenna, ...
ACS medicinal chemistry letters 5 (8), 927-930, 2014
542014
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic …
S Biswas, M Aggarwal, Ö Güzel, A Scozzafava, R McKenna, CT Supuran
Bioorganic & medicinal chemistry 19 (12), 3732-3738, 2011
542011
A large number of the human microRNAs target lentiviruses, retroviruses, and endogenous retroviruses
ST Hakim, M Alsayari, DC McLean, S Saleem, KC Addanki, M Aggarwal, ...
Biochemical and biophysical research communications 369 (2), 357-362, 2008
542008
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit α- and β-Carbonic Anhydrase: X-ray …
AM Marini, A Maresca, M Aggarwal, E Orlandini, S Nencetti, F Da Settimo, ...
Journal of Medicinal Chemistry 55 (22), 9619-9629, 2012
432012
" To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation
A Kovalevsky, M Aggarwal, H Velazquez, MJ Cuneo, MP Blakeley, ...
Structure 26 (3), 383-390. e3, 2018
412018
Neural control of dopamine neurotransmission: implications for reinforcement learning
M Aggarwal, BI Hyland, JR Wickens
European Journal of Neuroscience 35 (7), 1115-1123, 2012
412012
Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles
M Aggarwal, B Kondeti, C Tu, CM Maupin, DN Silverman, R McKenna
IUCrJ 1 (2), 129-135, 2014
402014
Triplex-forming MicroRNAs form stable complexes with HIV-1 provirus and inhibit its replication
M Kanak, M Alseiari, P Balasubramanian, K Addanki, M Aggarwal, ...
Applied Immunohistochemistry & Molecular Morphology 18 (6), 532-545, 2010
372010
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