| Generation of human induced pluripotent stem cells from oral mucosa K Miyoshi, D Tsuji, K Kudoh, K Satomura, T Muto, K Itoh, T Noma Journal of bioscience and bioengineering 110 (3), 345-350, 2010 | 140 | 2010 |
| Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells A Nakano, D Tsuji, H Miki, Q Cui, SME Sayed, A Ikegame, A Oda, H Amou, ... PloS one 6 (11), e27222, 2011 | 131 | 2011 |
| Highly phosphomannosylated enzyme replacement therapy for GM2 gangliosidosis D Tsuji, H Akeboshi, K Matsuoka, H Yasuoka, E Miyasaki, Y Kasahara, ... Annals of neurology 69 (4), 691-701, 2011 | 95 | 2011 |
| Therapeutic potential of intracerebroventricular replacement of modified human β-hexosaminidase B for GM2 gangliosidosis K Matsuoka, T Tamura, D Tsuji, Y Dohzono, K Kitakaze, K Ohno, S Saito, ... Molecular Therapy 19 (6), 1017-1024, 2011 | 86 | 2011 |
| Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma M Hiasa, J Teramachi, A Oda, R Amachi, T Harada, S Nakamura, H Miki, ... Leukemia 29 (1), 207-217, 2015 | 75 | 2015 |
| Chemical synthesis of biologically active monoglycosylated GM2-activator protein analogue using N-sulfanylethylanilide peptide. K Sato, A Shigenaga, K Kitakaze, K Sakamoto, D Tsuji, K Itoh, A Otaka Angewandte Chemie 125 (30), 2013 | 66 | 2013 |
| Production of recombinant β-hexosaminidase A, a potential enzyme for replacement therapy for Tay-Sachs and Sandhoff diseases, in the methylotrophic yeast Ogataea minuta H Akeboshi, Y Chiba, Y Kasahara, M Takashiba, Y Takaoka, M Ohsawa, ... Applied and environmental microbiology 73 (15), 4805-4812, 2007 | 64 | 2007 |
| Synthesis of a stimulus-responsive processing device and its application to a nucleocytoplasmic shuttle peptide A Shigenaga, D Tsuji, N Nishioka, S Tsuda, K Itoh, A Otaka ChemBioChem 8 (16), 1929-1931, 2007 | 61 | 2007 |
| Binding parameters and thermodynamics of the interaction of imino sugars with a recombinant human acid α-glucosidase (alglucosidase alfa): Insight into the complex formation … M Yoshimizu, Y Tajima, F Matsuzawa, S Aikawa, K Iwamoto, T Kobayashi, ... Clinica Chimica Acta 391 (1-2), 68-73, 2008 | 58 | 2008 |
| In vivo crystallography at X-ray free-electron lasers: the next generation of structural biology? FX Gallat, N Matsugaki, NP Coussens, KJ Yagi, M Boudes, T Higashi, ... Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 52 | 2014 |
| Specific induction of macrophage inflammatory protein 1‐α in glial cells of Sandhoff disease model mice associated with accumulation of N‐acetylhexosaminyl … D Tsuji, A Kuroki, Y Ishibashi, T Itakura, J Kuwahara, S Yamanaka, K Itoh Journal of neurochemistry 92 (6), 1497-1507, 2005 | 51 | 2005 |
| Production of human β-hexosaminidase A with highly phosphorylated N-glycans by the overexpression of the Ogataea minuta MNN4 gene H Akeboshi, Y Kasahara, D Tsuji, K Itoh, H Sakuraba, Y Chiba, Y Jigami Glycobiology 19 (9), 1002-1009, 2009 | 43 | 2009 |
| Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation DJ Hanson, S Nakamura, R Amachi, M Hiasa, A Oda, D Tsuji, K Itoh, ... Oncotarget 6 (32), 33568, 2015 | 42 | 2015 |
| Correlation analyses on binding affinity of sialic acid analogues and anti-influenza drugs with human neuraminidase using ab initio MO calculations on their complex structures … S Hitaoka, H Matoba, M Harada, T Yoshida, D Tsuji, T Hirokawa, K Itoh, ... Journal of chemical information and modeling 51 (10), 2706-2716, 2011 | 41 | 2011 |
| Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease T Kodama, T Togawa, T Tsukimura, I Kawashima, K Matsuoka, K Kitakaze, ... PLoS One 6 (12), e29074, 2011 | 39 | 2011 |
| Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model K Kitakaze, Y Mizutani, E Sugiyama, C Tasaki, D Tsuji, N Maita, ... The Journal of clinical investigation 126 (5), 1691-1703, 2016 | 38 | 2016 |
| Metabolic correction in microglia derived from Sandhoff disease model mice D Tsuji, A Kuroki, Y Ishibashi, T Itakura, K Itoh Journal of neurochemistry 94 (6), 1631-1638, 2005 | 35 | 2005 |
| Small molecule antibody targeting HLA class I inhibits myeloma cancer stem cells by repressing pluripotency-associated transcription factors A Ikegame, S Ozaki, D Tsuji, T Harada, S Fujii, S Nakamura, H Miki, ... Leukemia 26 (9), 2124-2134, 2012 | 34 | 2012 |
| Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosis N Kawashima, D Tsuji, T Okuda, K Itoh, K Nakayama Journal of neurochemistry 111 (4), 1031-1041, 2009 | 32 | 2009 |
| Combination with a defucosylated anti-HM1. 24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors T Harada, S Ozaki, A Oda, D Tsuji, A Ikegame, M Iwasa, K Udaka, S Fujii, ... PLoS One 8 (12), e83905, 2013 | 26 | 2013 |
Keisuke KitakazeKawasaki Medical School, 川崎医科大学確認したメール アドレス: med.kawasaki-m.ac.jp
