XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia NC Hoch, H Hanzlikova, SL Rulten, M Tétreault, E Komulainen, L Ju, ... Nature 541 (7635), 87-91, 2017 | 243 | 2017 |
ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022 | 178 | 2022 |
The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling LC Russo, R Tomasin, IA Matos, AC Manucci, ST Sowa, K Dale, ... Journal of Biological Chemistry 297 (3), 2021 | 80 | 2021 |
PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2 GJ Grundy, LM Polo, Z Zeng, SL Rulten, NC Hoch, P Paomephan, Y Xu, ... Nature communications 7 (1), 12404, 2016 | 76 | 2016 |
ATM substrate Chk2-interacting Zn2+ finger (ASCIZ) Is a bi-functional transcriptional activator and feedback sensor in the regulation of dynein light chain (DYNLL1) expression S Jurado, LA Conlan, EK Baker, JL Ng, N Tenis, NC Hoch, K Gleeson, ... Journal of Biological Chemistry 287 (5), 3156-3164, 2012 | 74 | 2012 |
ADP-ribosylation: from molecular mechanisms to human disease NC Hoch, LM Polo Genetics and Molecular Biology 43, e20190075, 2019 | 48 | 2019 |
DNA damage in tissues and organs of mice treated with diphenyl diselenide RM Rosa, NC Hoch, GV Furtado, J Saffi, JAP Henriques Mutation Research/Genetic Toxicology and Environmental Mutagenesis 633 (1 …, 2007 | 43 | 2007 |
Molecular basis of the essential s phase function of the rad53 checkpoint kinase NC Hoch, ESW Chen, R Buckland, SC Wang, A Fazio, A Hammet, ... Molecular and cellular biology 33 (16), 3202-3213, 2013 | 29 | 2013 |
Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo ESW Chen, NC Hoch, SC Wang, A Pellicioli, J Heierhorst, MD Tsai Molecular & Cellular Proteomics 13 (2), 551-565, 2014 | 25 | 2014 |
Host ADP-ribosylation and the SARS-CoV-2 macrodomain NC Hoch Biochemical Society Transactions 49 (4), 1711-1721, 2021 | 16 | 2021 |
The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand … C Breslin, RS Mani, M Fanta, N Hoch, M Weinfeld, KW Caldecott Journal of Biological Chemistry 292 (39), 16024-16031, 2017 | 16 | 2017 |
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress R Liu, A King, NC Hoch, C Chang, GL Kelly, AJ Deans, J Heierhorst DNA repair 57, 29-34, 2017 | 13 | 2017 |
Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia A King, NC Hoch, NE McGregor, NA Sims, IM Smyth, J Heierhorst Human Molecular Genetics 28 (15), 2573-2588, 2019 | 11 | 2019 |
Allelism of Saccharomyces cerevisiae gene PSO10, involved in error-prone repair of psoralen-induced DNA damage, with SUMO ligase-encoding MMS21 NC Hoch, RS Santos, RM Rosa, RM Machado, J Saffi, M Brendel, ... Current genetics 53, 361-371, 2008 | 7 | 2008 |
Tissue specificity of DNA damage and repair NC Hoch Physiology 38 (5), 231-241, 2023 | 6 | 2023 |
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide MT Latancia, NC Moreno, GS Leandro, VC Ribeiro, I de Souza, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 878, 503498, 2022 | 5 | 2022 |
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity A Serrano‐Benitez, SE Wells, L Drummond‐Clarke, LC Russo, ... The EMBO Journal 42 (18), e113190, 2023 | 3 | 2023 |
Biallelic variants in DNA2 cause poikiloderma with congenital cataracts and severe growth failure reminiscent of Rothmund-Thomson syndrome R Di Lazzaro Filho, GL Yamamoto, TJ Silva, LA Rocha, BDW Linnenkamp, ... Journal of medical genetics 60 (11), 1127-1132, 2023 | 2 | 2023 |
Where do we aspire to publish? A position paper on scientific communication in biochemistry and molecular biology MS Baptista, MJM Alves, GM Arantes, HA Armelin, O Augusto, RL Baldini, ... Brazilian Journal of Medical and Biological Research 52, e8935, 2019 | 2 | 2019 |
Genomic stability disorders: from budding yeast to humans NC Hoch, X Lai, J Heierhorst Front Biosci 5, 396-411, 2013 | 2 | 2013 |