| Reconstitution of membrane proteins in phospholipid bilayer nanodiscs TK Ritchie, YV Grinkova, TH Bayburt, IG Denisov, JK Zolnerciks, ... Methods in enzymology 464, 211-231, 2009 | 983 | 2009 |
| Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins A Nath, WM Atkins, SG Sligar Biochemistry 46 (8), 2059-2069, 2007 | 538 | 2007 |
| Human cytochrome P-450 3A4: in vitro drug-drug interaction patterns are substrate-dependent RW Wang, DJ Newton, N Liu, WM Atkins, AYH Lu Drug Metabolism and Disposition 28 (3), 360-366, 2000 | 340 | 2000 |
| A conserved residue of cytochrome P-450 is involved in heme-oxygen stability and activation SA Martinis, WM Atkins, PS Stayton, SG Sligar Journal of the American Chemical Society 111 (26), 9252-9253, 1989 | 333 | 1989 |
| The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis. WM Atkins, SG Sligar Journal of Biological Chemistry 263 (35), 18842-18849, 1988 | 263 | 1988 |
| Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions WM Atkins Annu. Rev. Pharmacol. Toxicol. 45, 291-310, 2005 | 250 | 2005 |
| Considerations for the design of antibody-based therapeutics DR Goulet, WM Atkins Journal of pharmaceutical sciences 109 (1), 74-103, 2020 | 212 | 2020 |
| Metabolic switching in cyctochrome P-450cam: deuterium isotope effects on regiospecificity and the monooxygenase/oxidase ratio WM Atkins, SG Sligar Journal of the American Chemical Society 109 (12), 3754-3760, 1987 | 156 | 1987 |
| Impact of linker and conjugation chemistry on antigen binding, Fc receptor binding and thermal stability of model antibody-drug conjugates M Acchione, H Kwon, CM Jochheim, WM Atkins MAbs 4 (3), 362-372, 2012 | 146 | 2012 |
| The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases S Mahajan, WM Atkins Cellular and Molecular Life Sciences CMLS 62, 1221-1233, 2005 | 142 | 2005 |
| The catalytic mechanism of glutathione S-transferase (GST). Spectroscopic determination of the pKa of Tyr-9 in rat alpha 1-1 GST. WM Atkins, RW Wang, AW Bird, DJ Newton, AY Lu Journal of Biological Chemistry 268 (26), 19188-19191, 1993 | 137 | 1993 |
| Molecular recognition in cytochrome P-450: alteration of regioselective alkane hydroxylation via protein engineering WM Atkins, SG Sligar Journal of the American Chemical Society 111 (7), 2715-2717, 1989 | 133 | 1989 |
| Allosteric behavior in cytochrome P450-dependent in vitro drug− drug interactions: A prospective based on conformational dynamics WM Atkins, RW Wang, AYH Lu Chemical research in toxicology 14 (4), 338-347, 2001 | 118 | 2001 |
| Interactions of glutathione transferases with 4-hydroxynonenal LM Balogh, WM Atkins Drug metabolism reviews 43 (2), 165-178, 2011 | 112 | 2011 |
| Deuterium isotope effects in norcamphor metabolism by cytochrome P-450cam: kinetic evidence for the two-electron reduction of a high-valent iron-oxo intermediate WM Atkins, SG Sligar Biochemistry 27 (5), 1610-1616, 1988 | 111 | 1988 |
| Self-assembly and gelation of oxidized glutathione in organic solvents RP Lyon, WM Atkins Journal of the American Chemical Society 123 (19), 4408-4413, 2001 | 107 | 2001 |
| A quantitative index of substrate promiscuity A Nath, WM Atkins Biochemistry 47 (1), 157-166, 2008 | 104 | 2008 |
| Pyrene⊙ pyrene complexes at the active site of cytochrome P450 3A4: Evidence for a multiple substrate binding site MJ Dabrowski, ML Schrag, LC Wienkers, WM Atkins Journal of the American Chemical Society 124 (40), 11866-11867, 2002 | 102 | 2002 |
| Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes A Nath, YV Grinkova, SG Sligar, WM Atkins Journal of biological chemistry 282 (39), 28309-28320, 2007 | 93 | 2007 |
| The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria AG Roberts, AP Campbell, WM Atkins Biochemistry 44 (4), 1353-1366, 2005 | 93 | 2005 |
