Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules C Liu, Z Xu, D Gupta, R Dziarski Journal of Biological Chemistry 276 (37), 34686-34694, 2001 | 492 | 2001 |
The peptidoglycan recognition proteins (PGRPs) R Dziarski, D Gupta Genome biology 7 (8), 232, 2006 | 429 | 2006 |
Peptidoglycan recognition proteins: modulators of the microbiome and inflammation J Royet, D Gupta, R Dziarski Nature Reviews Immunology 11 (12), 837-851, 2011 | 399 | 2011 |
Peptidoglycan recognition proteins are a new class of human bactericidal proteins X Lu, M Wang, J Qi, H Wang, X Li, D Gupta, R Dziarski Journal of Biological Chemistry 281 (9), 5895-5907, 2006 | 310 | 2006 |
Staphylococcus aureus Peptidoglycan Is a Toll-Like Receptor 2 Activator: a Reevaluation R Dziarski, D Gupta Infection and immunity 73 (8), 5212-5216, 2005 | 300 | 2005 |
Pglyrp-Regulated Gut Microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii Enhance and Alistipes finegoldii Attenuates Colitis in … R Dziarski, SY Park, DR Kashyap, SE Dowd, D Gupta PloS one 11 (1), e0146162, 2016 | 298 | 2016 |
CD14 is a cell-activating receptor for bacterial peptidoglycan D Gupta, TN Kirkland, S Viriyakosol, R Dziarski Journal of Biological Chemistry 271 (38), 23310-23316, 1996 | 284 | 1996 |
MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their … R Dziarski, Q Wang, K Miyake, CJ Kirschning, D Gupta The Journal of Immunology 166 (3), 1938-1944, 2001 | 277 | 2001 |
Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase ZM Wang, X Li, RR Cocklin, M Wang, M Wang, K Fukase, S Inamura, ... Journal of Biological Chemistry 278 (49), 49044-49052, 2003 | 273 | 2003 |
Micrococci and peptidoglycan activate TLR2→ MyD88→ IRAK→ TRAF→ NIK→ IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8 Q Wang, R Dziarski, CJ Kirschning, M Muzio, D Gupta Infection and immunity 69 (4), 2270-2276, 2001 | 235 | 2001 |
Mammalian peptidoglycan recognition proteins (PGRPs) in innate immunity R Dziarski, D Gupta Innate immunity 16 (3), 168-174, 2010 | 216 | 2010 |
Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)–deficient mice R Dziarski, KA Platt, E Gelius, H Steiner, D Gupta Blood 102 (2), 689-697, 2003 | 207 | 2003 |
Peptidoglycan recognition proteins kill bacteria by activating protein-sensing two-component systems DR Kashyap, M Wang, LH Liu, GJ Boons, D Gupta, R Dziarski Nature medicine 17 (6), 676-683, 2011 | 197 | 2011 |
Differential Activation of Extracellular Signal-Regulated Kinase (ERK) 1, ERK2, p38, and c-Jun NH2-Terminal Kinase Mitogen-Activated Protein Kinases by … R Dziarski, Y Jin, D Gupta Journal of Infectious Diseases 174 (4), 777-785, 1996 | 167 | 1996 |
Mammalian PGRPs: novel antibacterial proteins R Dziarski, D Gupta Cellular microbiology 8 (7), 1059-1069, 2006 | 148 | 2006 |
Role of MD-2 in TLR2-and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes R Dziarski, D Gupta Journal of endotoxin research 6 (5), 401-405, 2000 | 148 | 2000 |
Peptidoglycan recognition in innate immunity R Dziarski, D Gupta Journal of endotoxin research 11 (5), 304-310, 2005 | 147 | 2005 |
Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-γ S Saha, X Jing, SY Park, S Wang, X Li, D Gupta, R Dziarski Cell host & microbe 8 (2), 147-162, 2010 | 145 | 2010 |
Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections X Li, S Wang, J Qi, SF Echtenkamp, R Chatterjee, M Wang, GJ Boons, ... Immunity 27 (3), 518-529, 2007 | 145 | 2007 |
Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides M Wang, LH Liu, S Wang, X Li, X Lu, D Gupta, R Dziarski The Journal of Immunology 178 (5), 3116-3125, 2007 | 136 | 2007 |