| Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells KL VanDussen, AJ Carulli, TM Keeley, SR Patel, BJ Puthoff, ST Magness, ... Development 139 (3), 488-497, 2012 | 618 | 2012 |
| Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays KL VanDussen, JM Marinshaw, N Shaikh, H Miyoshi, C Moon, PI Tarr, ... Gut 64 (6), 911-920, 2015 | 483 | 2015 |
| Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis C Moon, KL VanDussen, H Miyoshi, TS Stappenbeck Mucosal immunology 7 (4), 818-828, 2014 | 250 | 2014 |
| Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium H Miyoshi, KL VanDussen, NP Malvin, SH Ryu, Y Wang, NM Sonnek, ... The EMBO journal 36 (1), 5-24, 2017 | 219 | 2017 |
| Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease KL VanDussen, TC Liu, D Li, F Towfic, N Modiano, R Winter, ... Gastroenterology 146 (1), 200-209, 2014 | 210 | 2014 |
| Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate KL VanDussen, LC Samuelson Developmental biology 346 (2), 215-223, 2010 | 181 | 2010 |
| Long-term culture captures injury-repair cycles of colonic stem cells Y Wang, IL Chiang, TE Ohara, S Fujii, J Cheng, BD Muegge, A Ver Heul, ... Cell 179 (5), 1144-1159. e15, 2019 | 150 | 2019 |
| A stem-cell-derived platform enables complete Cryptosporidium development in vitro and genetic tractability G Wilke, LJ Funkhouser-Jones, Y Wang, S Ravindran, Q Wang, WL Beatty, ... Cell host & microbe 26 (1), 123-134. e8, 2019 | 130 | 2019 |
| Epithelial indoleamine 2, 3-dioxygenase 1 modulates aryl hydrocarbon receptor and notch signaling to increase differentiation of secretory cells and alter mucus-associated … DM Alvarado, B Chen, M Iticovici, AI Thaker, N Dai, KL VanDussen, ... Gastroenterology 157 (4), 1093-1108. e11, 2019 | 98 | 2019 |
| Notch signaling regulates gastric antral LGR 5 stem cell function ES Demitrack, GB Gifford, TM Keeley, AJ Carulli, KL VanDussen, ... The EMBO journal 34 (20), 2522-2536, 2015 | 95 | 2015 |
| Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate L López-Díaz, RN Jain, TM Keeley, KL VanDussen, CS Brunkan, ... Developmental biology 309 (2), 298-305, 2007 | 93 | 2007 |
| ADAM10 regulates Notch function in intestinal stem cells of mice YH Tsai, KL VanDussen, ET Sawey, AW Wade, C Kasper, S Rakshit, ... Gastroenterology 147 (4), 822-834. e13, 2014 | 90 | 2014 |
| L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams KL VanDussen, NM Sonnek, TS Stappenbeck Stem Cell Research 37, 101430, 2019 | 89 | 2019 |
| Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation TC Liu, JT Kern, U Jain, NM Sonnek, S Xiong, KF Simpson, ... Cell host & microbe 29 (6), 988-1001. e6, 2021 | 81 | 2021 |
| Abnormal small intestinal epithelial microvilli in patients with Crohn's disease KL VanDussen, A Stojmirović, K Li, TC Liu, PK Kimes, BD Muegge, ... Gastroenterology 155 (3), 815-828, 2018 | 77 | 2018 |
| Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn’s disease TC Liu, JT Kern, KL VanDussen, S Xiong, GE Kaiko, CB Wilen, ... The Journal of clinical investigation 128 (11), 5110-5122, 2018 | 74 | 2018 |
| LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn’s disease patients TC Liu, T Naito, Z Liu, KL VanDussen, T Haritunians, D Li, K Endo, ... JCI insight 2 (6), 2017 | 58 | 2017 |
| PAI-1 augments mucosal damage in colitis GE Kaiko, F Chen, CW Lai, IL Chiang, J Perrigoue, A Stojmirović, K Li, ... Science translational medicine 11 (482), eaat0852, 2019 | 56 | 2019 |
| Temporal regulation of the bacterial metabolite deoxycholate during colonic repair is critical for crypt regeneration U Jain, CW Lai, S Xiong, VM Goodwin, Q Lu, BD Muegge, GP Christophi, ... Cell host & microbe 24 (3), 353-363. e5, 2018 | 51 | 2018 |
| Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model KM Seiler, A Bajinting, DM Alvarado, MA Traore, MM Binkley, WH Goo, ... Scientific reports 10 (1), 3842, 2020 | 39 | 2020 |
Chin-wen LaiSenior Scientist, Variant BioVerified email at amgen.com
