The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation R Wang, CP Dillon, LZ Shi, S Milasta, R Carter, D Finkelstein, ... Immunity 35 (6), 871-882, 2011 | 2088 | 2011 |
Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis A Oberst, CP Dillon, R Weinlich, LL McCormick, P Fitzgerald, C Pop, ... Nature 471 (7338), 363-367, 2011 | 1305 | 2011 |
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release M Schuler, E Bossy-Wetzel, JC Goldstein, P Fitzgerald, DR Green Journal of Biological Chemistry 275 (10), 7337-7342, 2000 | 712 | 2000 |
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain JE Ricci, C Muñoz-Pinedo, P Fitzgerald, B Bailly-Maitre, GA Perkins, ... Cell 117 (6), 773-786, 2004 | 693 | 2004 |
Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells J Martinez, J Almendinger, A Oberst, R Ness, CP Dillon, P Fitzgerald, ... Proceedings of the National Academy of Sciences 108 (42), 17396-17401, 2011 | 691 | 2011 |
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation A Colell, JE Ricci, S Tait, S Milasta, U Maurer, L Bouchier-Hayes, ... Cell 129 (5), 983-997, 2007 | 593 | 2007 |
ESCRT-III acts downstream of MLKL to regulate necroptotic cell death and its consequences YN Gong, C Guy, H Olauson, JU Becker, M Yang, P Fitzgerald, ... Cell 169 (2), 286-300. e16, 2017 | 573 | 2017 |
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice M Saleh, JC Mathison, MK Wolinski, SJ Bensinger, P Fitzgerald, N Droin, ... Nature 440 (7087), 1064-1068, 2006 | 405 | 2006 |
The cytotoxic cell protease granzyme B initiates apoptosis in a cell‐free system by proteolytic processing and activation of the ICE/CED‐3 family protease, CPP32, via a novel … SJ Martin, GP Amarante‐Mendes, L Shi, TH Chuang, CA Casiano, ... The EMBO journal 15 (10), 2407-2416, 1996 | 380 | 1996 |
Cell death and tissue remodeling in planarian regeneration J Pellettieri, P Fitzgerald, S Watanabe, J Mancuso, DR Green, ... Developmental biology 338 (1), 76-85, 2010 | 365 | 2010 |
Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis DA Rodriguez, R Weinlich, S Brown, C Guy, P Fitzgerald, CP Dillon, ... Cell Death & Differentiation 23 (1), 76-88, 2016 | 347 | 2016 |
Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration C Muñoz-Pinedo, A Guío-Carrión, JC Goldstein, P Fitzgerald, ... Proceedings of the National Academy of Sciences 103 (31), 11573-11578, 2006 | 279 | 2006 |
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling NH Philip, CP Dillon, AG Snyder, P Fitzgerald, MA Wynosky-Dolfi, ... Proceedings of the National Academy of Sciences 111 (20), 7385-7390, 2014 | 272 | 2014 |
BID-induced structural changes in BAK promote apoptosis T Moldoveanu, CR Grace, F Llambi, A Nourse, P Fitzgerald, K Gehring, ... Nature structural & molecular biology 20 (5), 589-597, 2013 | 237 | 2013 |
Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1, 25-dihydroxyvitamin D3 MF Boehm, P Fitzgerald, A Zou, MG Elgort, ED Bischoff, L Mere, DE Mais, ... Chemistry & biology 6 (5), 265-275, 1999 | 181 | 1999 |
Cutting edge: endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8–and TRIF-dependent pathway K Shenderov, N Riteau, R Yip, KD Mayer-Barber, S Oland, S Hieny, ... The Journal of Immunology 192 (5), 2029-2033, 2014 | 177 | 2014 |
Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway D Rousseau, D Cannella, J Boulaire, P Fitzgerald, A Fotedar, R Fotedar Oncogene 18 (21), 3290-3302, 1999 | 172 | 1999 |
Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status P Fitzgerald, M Teng, RAS Chandraratna, RA Heyman, EA Allegretto Cancer research 57 (13), 2642-2650, 1997 | 158 | 1997 |
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity BB Wolf, M Schuler, W Li, B Eggers-Sedlet, W Lee, P Tailor, P Fitzgerald, ... Journal of Biological Chemistry 276 (36), 34244-34251, 2001 | 155 | 2001 |
Role of proteolysis in caspase-8 activation and stabilization C Pop, P Fitzgerald, DR Green, GS Salvesen Biochemistry 46 (14), 4398-4407, 2007 | 152 | 2007 |