Screening study for potential lead compounds for natural product‐based fungicides: I. Synthesis and in vitro evaluation of coumarins against Botrytis cinerea M Daoubi, R Durán‐Patrón, M Hmamouchi, R Hernández‐Galán, ... Pest management science 60 (9), 927-932, 2004 | 68 | 2004 |
Screening study of lead compounds for natural product-based fungicides: antifungal activity and biotransformation of 6α, 7α-dihydroxy-β-himachalene by Botrytis cinerea M Daoubi, R Hernández-Galán, A Benharref, IG Collado Journal of agricultural and food chemistry 53 (17), 6673-6677, 2005 | 66 | 2005 |
Isolation of new phenylacetylingol derivatives that reactivate HIV-1 latency and a novel spirotriterpenoid from Euphorbia officinarum latex M Daoubi, N Marquez, N Mazoir, A Benharref, R Hernández-Galán, ... Bioorganic & medicinal chemistry 15 (13), 4577-4584, 2007 | 63 | 2007 |
Antifungal Activity and Biotransformation of Diisophorone by Botrytis cinerea M Daoubi, A Deligeorgopoulou, AJ Macías-Sánchez, R Hernández-Galán, ... Journal of agricultural and food chemistry 53 (15), 6035-6039, 2005 | 62 | 2005 |
Piperidino-pyrimidine derivatives for the treatment of viral infections DC McGowan, PJMB Raboisson, THM Jonckers, MD Khamlichi US Patent 9,133,192, 2015 | 61 | 2015 |
Novel pyrimidine toll-like receptor 7 and 8 dual agonists to treat hepatitis B virus D McGowan, F Herschke, F Pauwels, B Stoops, S Last, S Pieters, ... Journal of Medicinal Chemistry 59 (17), 7936-7949, 2016 | 35 | 2016 |
Hemisynthesis and absolute configuration of novel 6-pentyl-2H-pyran-2-one derivatives from Trichoderma spp. M Daoubi, C Pinedo-Rivilla, MB Rubio, R Hermosa, E Monte, J Aleu, ... Tetrahedron 65 (25), 4834-4840, 2009 | 30 | 2009 |
Biosynthetic Studies on the Botcinolide Skeleton: New Hydroxylated Lactones from Botrytis cinerea JL Reino, RM Durán-Patrón, M Daoubi, IG Collado, R Hernández-Galán The Journal of Organic Chemistry 71 (2), 562-565, 2006 | 28 | 2006 |
ELAC (3,12‐di‐O‐acetyl‐8‐O‐tigloilingol), a plant‐derived lathyrane diterpene, induces subventricular zone neural progenitor cell proliferation through PKCβ … M Murillo‐Carretero, N Geribaldi‐Doldán, E Flores‐Giubi, ... British Journal of Pharmacology 174 (14), 2373-2392, 2017 | 27 | 2017 |
Piperidino-pyrimidine derivatives for the treatment of viral infections DC McGowan, PJMB Raboisson, THM Jonckers, MD Khamlichi US Patent 9,365,571, 2016 | 26 | 2016 |
Two novel steroids from Euphorbia officinarum latex M Daoubi, A Benharref, R Hernandez-Galan, AJ Macías-Sánchez, ... Natural product research 18 (2), 177-181, 2004 | 23 | 2004 |
Antimicrobial Activity of two Semisynthetic Triterpene Derivatives from Euphorbia Officinarum Latex Against Fungal and Bacterial Phytopathogens A Smaili, N Mazoir, LA Rifai, T Koussa, K Makroum, A Benharref, L Faize, ... Natural Product Communications 12 (3), 1934578X1701200305, 2017 | 22 | 2017 |
The role of botrydienediol in the biodegradation of the sesquiterpenoid phytotoxin botrydial by Botrytis cinerea M Daoubi, R Durán-Patrón, R Hernández-Galán, A Benharref, JR Hanson, ... Tetrahedron 62 (35), 8256-8261, 2006 | 18 | 2006 |
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B DC McGowan, F Herschke, F Pauwels, B Stoops, I Smyej, S Last, ... Journal of Medicinal Chemistry 60 (14), 6137-6151, 2017 | 15 | 2017 |
Lipase-catalyzed resolution of 5-acetoxy-1, 2-dihydroxy-1, 2, 3, 4-tetrahydronaphthalene. Application to the synthesis of (+)-(3R, 4S)-cis-4-hydroxy-6-deoxyscytalone, a … D Jiménez-Teja, M Daoubi, IG Collado, R Hernández-Galán Tetrahedron 65 (17), 3392-3396, 2009 | 14 | 2009 |
Discovery of selective 2, 4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists S Pieters, D McGowan, F Herschke, F Pauwels, B Stoops, S Last, ... Bioorganic & Medicinal Chemistry Letters 28 (4), 711-719, 2018 | 13 | 2018 |
Hemisynthesis of New Triterpene Derivatives using Oxidation by CrO3 and NaIO4‐(RuCl3, 3H2O) N Mazoir, A Auhmani, M Daoubi, IG Collado, A Benharref Synthetic communications 37 (8), 1289-1299, 2007 | 13 | 2007 |
Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists DC McGowan, F Herschke, MD Khamlichi, ML Rosauro, SMP Benedicto, ... Bioorganic & Medicinal Chemistry Letters 28 (19), 3216-3221, 2018 | 10 | 2018 |
New Bioactive Semisynthetic Derivatives of 31-Norlanostenol and Obtusifoliol from Euphorbia Officinarum M Bailen, MD Khamlichi, A Benharref, RA Martinez-Diaz, ... Natural Product Communications 11 (6), 1934578X1601100609, 2016 | 10 | 2016 |
1H and 13C NMR structural study of products obtained by hemisynthesis on the triterpenes isolated from latex of Euphorbia officinarum N Mazoir, A Liazid, A Auhmani, M Daoubi, M Dakir, A Benharref, A Kenz, ... Physical & chemical news, 123-128, 2005 | 10 | 2005 |