| Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases H Zhong, AM De Marzo, E Laughner, M Lim, DA Hilton, D Zagzag, ... Cancer research 59 (22), 5830-5835, 1999 | 3120 | 1999 |
| Angiogenesis as a therapeutic target N Ferrara, RS Kerbel Nature 438 (7070), 967, 2005 | 2749 | 2005 |
| Tumor angiogenesis RS Kerbel New England Journal of Medicine 358 (19), 2039-2049, 2008 | 2289 | 2008 |
| Clinical translation of angiogenesis inhibitors R Kerbel, J Folkman Nature Reviews Cancer 2 (10), 727, 2002 | 1862 | 2002 |
| Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis JML Ebos, CR Lee, W Cruz-Munoz, GA Bjarnason, JG Christensen, ... Cancer cell 15 (3), 232-239, 2009 | 1804 | 2009 |
| The anti-angiogenic basis of metronomic chemotherapy RS Kerbel, BA Kamen Nature Reviews Cancer 4 (6), 423, 2004 | 1383 | 2004 |
| Tumor angiogenesis: past, present and the near future RS Kerbel Carcinogenesis 21 (3), 505-515, 2000 | 1357 | 2000 |
| Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity G Klement, S Baruchel, J Rak, S Man, K Clark, DJ Hicklin, P Bohlen, ... The Journal of clinical investigation 105 (8), R15-R24, 2000 | 1346 | 2000 |
| Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis JW Dennis, S Laferte, C Waghorne, ML Breitman, RS Kerbel Science 236 (4801), 582-585, 1987 | 1021 | 1987 |
| Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in … AM Petit, J Rak, MC Hung, P Rockwell, N Goldstein, B Fendly, RS Kerbel The American journal of pathology 151 (6), 1523, 1997 | 966 | 1997 |
| Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis J Rak, Y Mitsuhashi, L Bayko, J Filmus, S Shirasawa, T Sasazuki, ... Cancer research 55 (20), 4575-4580, 1995 | 935 | 1995 |
| Establishment and characterization of first trimester human trophoblast cells with extended lifespan CH Graham, TS Hawley, RC Hawley, JR MacDougall, RS Kerbel, N Khoo, ... Experimental cell research 206 (2), 204-211, 1993 | 783 | 1993 |
| The multifaceted circulating endothelial cell in cancer: towards marker and target identification F Bertolini, Y Shaked, P Mancuso, RS Kerbel Nature Reviews Cancer 6 (11), 835, 2006 | 634 | 2006 |
| Antiangiogenic therapy: impact on invasion, disease progression, and metastasis JML Ebos, RS Kerbel Nature reviews Clinical oncology 8 (4), 210, 2011 | 616 | 2011 |
| Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis A Viloria-Petit, T Crombet, S Jothy, D Hicklin, P Bohlen, JM Schlaeppi, ... Cancer research 61 (13), 5090-5101, 2001 | 603 | 2001 |
| Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors Y Shaked, A Ciarrocchi, M Franco, CR Lee, S Man, AM Cheung, ... Science 313 (5794), 1785-1787, 2006 | 598 | 2006 |
| A role for survivin in chemoresistance of endothelial cells mediated by VEGF J Tran, Z Master, LY Joanne, J Rak, DJ Dumont, RS Kerbel Proceedings of the National Academy of Sciences 99 (7), 4349-4354, 2002 | 585 | 2002 |
| Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti‐cancer therapeutic agents RS Kerbel Bioessays 13 (1), 31-36, 1991 | 559 | 1991 |
| Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells F Bertolini, S Paul, P Mancuso, S Monestiroli, A Gobbi, Y Shaked, ... Cancer research 63 (15), 4342-4346, 2003 | 553 | 2003 |
| E-cadherin–dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27KIP1 BS Croix, C Sheehan, JW Rak, VA Flørenes, JM Slingerland, RS Kerbel The Journal of cell biology 142 (2), 557-571, 1998 | 541 | 1998 |