Evaluation of sperm proteins in infertile men: a proteomic approach S Thacker, SP Yadav, RK Sharma, A Kashou, B Willard, D Zhang, ... Fertility and sterility 95 (8), 2745-2748, 2011 | 85 | 2011 |
Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer IN Smith, S Thacker, M Seyfi, F Cheng, C Eng The American Journal of Human Genetics 104, 1-18, 2019 | 49 | 2019 |
Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype N Sarn, R Jaini, S Thacker, H Lee, R Dutta, C Eng Molecular Psychiatry, 2020 | 47 | 2020 |
Dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes IN Smith, S Thacker, R Jaini, C Eng Journal of Biomolecular Structure and Dynamics 37 (7), 1766-1782, 2019 | 40 | 2019 |
An integrated deep-mutational-scanning approach provides clinical insights on PTEN genotype-phenotype relationships TL Mighell, S Thacker, E Fombonne, C Eng, BJ O’Roak The American Journal of Human Genetics 106 (6), 818-829, 2020 | 38 | 2020 |
Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder Hyunpil, S Thacker, N Sarn, R Dutta, C Eng Translational Psychiatry 9 (1), 13, 2019 | 38 | 2019 |
Limb-and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia D Hubmacher, N Taye, Z Balic, S Thacker, SM Adams, DE Birk, ... Matrix Biology 82, 38-53, 2019 | 23 | 2019 |
Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits X He, S Thacker, T Romigh, Q Yu, TW Frazier, C Eng Molecular Autism 6, 1-10, 2015 | 22 | 2015 |
Alternative splicing landscape of the neural transcriptome in a cytoplasmic-predominant Pten expression murine model of autism-like Behavior S Thacker, M Seyfi, C Eng Translational Psychiatry 10, 2020 | 17 | 2020 |
Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity N Sarn, S Thacker, H Lee, C Eng Molecular Autism 12 (1), 41, 2021 | 16 | 2021 |
Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation SC Kang, R Jaini, M Hitomi, H Lee, N Sarn, S Thacker, C Eng Molecular Autism 11, 1-16, 2020 | 16 | 2020 |
Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice R Jaini, MG Loya, AT King, S Thacker, NB Sarn, Q Yu, GR Stark, C Eng Human Molecular Genetics 29 (14), 2353-2364, 2020 | 9 | 2020 |
Redefining the PTEN promoter: identification of novel upstream transcription start regions DJ Grencewicz, T Romigh, S Thacker, A Abbas, R Jaini, D Luse, C Eng Human Molecular Genetics 30 (22), 2135-2148, 2021 | 6 | 2021 |
Structural and dynamic effects of PTEN C-terminal tail phosphorylation IN Smith, JE Dawson, J Krieger, S Thacker, I Bahar, C Eng Journal of Chemical Information and Modeling 62 (17), 4175-4190, 2022 | 5 | 2022 |
Transcriptome-(phospho) proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes S Thacker, C Eng NPJ Genomic Medicine 6 (1), 42, 2021 | 4 | 2021 |
P420: Development of a comprehensive cardiovascular disease whole genome sequencing test L Amendola, A Coffey, S Strom, A Kesari, J Avecilla, J Lowry, S Thacker, ... Genetics in Medicine Open 1 (1), 2023 | | 2023 |
Redefining the PTEN Promoter: Identification of Two Upstream Transcription Start Regions D Grencewicz, T Romigh, S Thacker, A Abbas, R Jaini, D Luse, C Eng bioRxiv, 2021.04. 23.441162, 2021 | | 2021 |
An Exploration of the Molecular Pathogenesis of the Autism Component of PTEN Hamartoma Tumor Syndrome (PHTS): Towards an Understanding of PTEN Variation on PHTS Phenotype Diversity ST Thacker Case Western Reserve University, 2021 | | 2021 |
Transcriptome-(Phospho) proteome Characterization of the Brain of a Constitutional Model of Cytoplasmic-predominant Pten Expression With Autism-Like Phenotypes S Thacker, C Eng | | 2020 |
ARTICLE Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer IN Smith, S Thacker, M Seyfi, F Cheng, C Eng | | 2019 |