Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ... Nature 523 (7562), 561-567, 2015 | 832 | 2015 |
Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors XE Zhou, Y He, PW de Waal, X Gao, Y Kang, N Van Eps, Y Yin, K Pal, ... Cell 170 (3), 457-469. e13, 2017 | 393 | 2017 |
Activation of the A2A adenosine G-protein-coupled receptor by conformational selection L Ye, N Van Eps, M Zimmer, OP Ernst, R Scott Prosser Nature 533 (7602), 265-268, 2016 | 340 | 2016 |
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Y Kang, O Kuybeda, PW de Waal, S Mukherjee, N Van Eps, P Dutka, ... Nature 558 (7711), 553-558, 2018 | 251 | 2018 |
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm Nature structural & molecular biology 13 (9), 772-777, 2006 | 232 | 2006 |
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit N Van Eps, AM Preininger, N Alexander, AI Kaya, S Meier, J Meiler, ... Proceedings of the National Academy of Sciences 108 (23), 9420-9424, 2011 | 192 | 2011 |
Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe Q Cai, AK Kusnetzow, WL Hubbell, IS Haworth, GPC Gacho, N Van Eps, ... Nucleic acids research 34 (17), 4722-4730, 2006 | 156 | 2006 |
Conformation of receptor-bound visual arrestin M Kim, SA Vishnivetskiy, N Van Eps, NS Alexander, WM Cleghorn, ... Proceedings of the National Academy of Sciences 109 (45), 18407-18412, 2012 | 124 | 2012 |
Structure and function of the visual arrestin oligomer SM Hanson, N Van Eps, DJ Francis, C Altenbach, SA Vishnivetskiy, ... The EMBO journal 26 (6), 1726-1736, 2007 | 124 | 2007 |
Structure of the glucagon receptor in complex with a glucagon analogue H Zhang, A Qiao, L Yang, N Van Eps, KS Frederiksen, D Yang, A Dai, ... Nature 553 (7686), 106-110, 2018 | 114 | 2018 |
Conformational equilibria of light-activated rhodopsin in nanodiscs N Van Eps, LN Caro, T Morizumi, AK Kusnetzow, M Szczepek, ... Proceedings of the National Academy of Sciences 114 (16), E3268-E3275, 2017 | 103 | 2017 |
Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway N Van Eps, WM Oldham, HE Hamm, WL Hubbell Proceedings of the National Academy of Sciences 103 (44), 16194-16199, 2006 | 99 | 2006 |
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm Proceedings of the National Academy of Sciences 104 (19), 7927-7932, 2007 | 87 | 2007 |
Gi-and Gs-coupled GPCRs show different modes of G-protein binding N Van Eps, C Altenbach, LN Caro, NR Latorraca, SA Hollingsworth, ... Proceedings of the National Academy of Sciences 115 (10), 2383-2388, 2018 | 85 | 2018 |
A model for the solution structure of the rod arrestin tetramer SM Hanson, ES Dawson, DJ Francis, N Van Eps, CS Klug, WL Hubbell, ... Structure 16 (6), 924-934, 2008 | 82 | 2008 |
Cryo-EM structure of the native rhodopsin dimer in nanodiscs DY Zhao, M Pöge, T Morizumi, S Gulati, N Van Eps, J Zhang, P Miszta, ... Journal of Biological Chemistry 294 (39), 14215-14230, 2019 | 76 | 2019 |
The role of arrestin α-helix I in receptor binding SA Vishnivetskiy, D Francis, N Van Eps, M Kim, SM Hanson, CS Klug, ... Journal of molecular biology 395 (1), 42-54, 2010 | 73 | 2010 |
X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin T Morizumi, WL Ou, N Van Eps, K Inoue, H Kandori, LS Brown, OP Ernst Scientific Reports 9 (1), 11283, 2019 | 67 | 2019 |
The Myristoylated Amino Terminus of Gαi1 Plays a Critical Role in the Structure and Function of Gαi1 Subunits in Solution AM Preininger, N Van Eps, NJ Yu, M Medkova, WL Hubbell, HE Hamm Biochemistry 42 (26), 7931-7941, 2003 | 58 | 2003 |
The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1 N Van Eps, CJ Thomas, WL Hubbell, SR Sprang Proceedings of the National Academy of Sciences 112 (5), 1404-1409, 2015 | 37 | 2015 |