Ubiquitylation of nuclear receptors: new linkages and therapeutic implications KT Helzer, C Hooper, S Miyamoto, ET Alarid Journal of molecular endocrinology 54 (3), R151-R167, 2015 | 53 | 2015 |
The phosphorylated estrogen receptor α (ER) cistrome identifies a subset of active enhancers enriched for direct ER-DNA binding and the transcription factor GRHL2 KT Helzer, M Szatkowski Ozers, MB Meyer, NA Benkusky, N Solodin, ... Molecular and cellular biology 39 (3), e00417-18, 2019 | 32 | 2019 |
Prognosis associated with luminal and basal subtypes of metastatic prostate cancer R Aggarwal, NR Rydzewski, L Zhang, A Foye, W Kim, KT Helzer, ... JAMA oncology 7 (11), 1644-1652, 2021 | 23 | 2021 |
Longitudinal molecular profiling of circulating tumor cells in metastatic renal cell carcinoma M Bootsma, RR McKay, H Emamekhoo, RM Bade, JL Schehr, ... Journal of Clinical Oncology 40 (31), 3633, 2022 | 18 | 2022 |
Predicting cancer drug TARGETS-treatment response generalized elastic-neT signatures NR Rydzewski, E Peterson, JM Lang, M Yu, S Laura Chang, M Sjöström, ... NPJ genomic medicine 6 (1), 76, 2021 | 13 | 2021 |
17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes F Jallow, JL Brockman, KT Helzer, DE Rugowski, V Goffin, ET Alarid, ... Journal of the Endocrine Society 2 (3), 293-309, 2018 | 11 | 2018 |
Expression and therapeutic targeting of TROP-2 in treatment-resistant prostate cancer JM Sperger, KT Helzer, CN Stahlfeld, D Jiang, A Singh, KR Kaufmann, ... Clinical Cancer Research 29 (12), 2324-2335, 2023 | 9 | 2023 |
A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer SG Zhao, JM Sperger, JL Schehr, RR McKay, H Emamekhoo, A Singh, ... The Journal of Clinical Investigation 132 (21), 2022 | 8 | 2022 |
Intrinsic molecular subtypes of metastatic castration-resistant prostate cancer E Feng, NR Rydzewski, M Zhang, A Lundberg, M Bootsma, KT Helzer, ... Clinical Cancer Research 28 (24), 5396-5404, 2022 | 4 | 2022 |
GRHL2 enhances phosphorylated estrogen receptor (ER) chromatin binding and regulates ER-mediated transcriptional activation and repression RM Reese, KT Helzer, KO Allen, C Zheng, N Solodin, ET Alarid Molecular and Cellular Biology, 2022 | 4 | 2022 |
Fragmentomic analysis of circulating tumor DNA-targeted cancer panels KT Helzer, MN Sharifi, JM Sperger, Y Shi, M Annala, ML Bootsma, ... Annals of Oncology 34 (9), 813-825, 2023 | 3 | 2023 |
Identification of phenocopies improves prediction of targeted therapy response over DNA mutations alone H Bakhtiar, KT Helzer, Y Park, Y Chen, NR Rydzewski, ML Bootsma, ... npj Genomic Medicine 7 (1), 1-10, 2022 | 3 | 2022 |
GRHL2 enhances phosphorylated estrogen receptor DNA-binding and regulates ER-mediated transcriptional activation and repression RM Reese, KT Helzer, KO Allen, C Zheng, N Solodin, ET Alarid bioRxiv, 2022.05. 19.492733, 2022 | 1 | 2022 |
Application of exclusive liquid repellency for low input CUT&Tag histone analyses in prostate cancer spheroids ZJ Kauffman, K Koesser, KT Helzer, JM Sperger, MN Sharifi, C Li, ... Cancer Research 84 (6_Supplement), 7023-7023, 2024 | | 2024 |
A platform-independent AI tumor lineage and site (ATLAS) classifier NR Rydzewski, Y Shi, C Li, MR Chrostek, H Bakhtiar, KT Helzer, ... Communications Biology 7 (1), 314, 2024 | | 2024 |
Fragmentomics of cell-free DNA from targeted panels in genitourinary malignancies. AK Taylor, K Helzer, MN Sharifi, JM Sperger, Y Shi, M Annala, S Reese, ... Journal of Clinical Oncology 42 (4_suppl), 199-199, 2024 | | 2024 |
Machine Learning & Molecular Radiation Tumor Biomarkers NR Rydzewski, KT Helzer, M Bootsma, Y Shi, H Bakhtiar, M Sjöström, ... Seminars in Radiation Oncology 33 (3), 243-251, 2023 | | 2023 |
Abstract B016: Liquid biopsy biomarker analysis of a phase II trial of sacituzumab govitecan in castrate resistant metastatic prostate cancer JM Sperger, AK Taylor, Y Shi, CN Stahlfeld, K Helzer, M Bootsma, ... Cancer Research 83 (11_Supplement), B016-B016, 2023 | | 2023 |
Abstract A057: Microscale analysis of histone modifications in rare cell populations in prostate cancer ZJ Kauffman, K Koesser, KT Helzer, JM Sperger, MN Sharifi, C Li, ... Cancer Research 83 (11_Supplement), A057-A057, 2023 | | 2023 |
Molecular classification of cancer site of origin and lineage. NR Rydzewski, C Li, H Bakhtiar, Y Shi, K Helzer, M Bootsma, PM Harari, ... Journal of Clinical Oncology 41 (16_suppl), 3116-3116, 2023 | | 2023 |