Nicotinamide riboside is uniquely and orally bioavailable in mice and humans SAJ Trammell, MS Schmidt, BJ Weidemann, P Redpath, F Jaksch, ... Nature communications 7 (1), 12948, 2016 | 619 | 2016 |
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 329 | 2016 |
Speedy: a novel cell cycle regulator of the G2/M transition JL Lenormand, RW Dellinger, KE Knudsen, S Subramani, DJ Donoghue The EMBO journal, 1999 | 177 | 1999 |
Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo … RW Dellinger, SR Santos, M Morris, M Evans, D Alminana, L Guarente, ... npj Aging and Mechanisms of Disease 3 (1), 17, 2017 | 166 | 2017 |
Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2 LA Porter, RW Dellinger, JA Tynan, EA Barnes, M Kong, JL Lenormand, ... The Journal of cell biology 157 (3), 357-366, 2002 | 133 | 2002 |
Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy JM Estrela, S Mena, E Obrador, M Benlloch, G Castellano, R Salvador, ... Journal of medicinal chemistry 60 (23), 9413-9436, 2017 | 132 | 2017 |
Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases D Sun, AK Sharma, RW Dellinger, AS Blevins-Primeau, RM Balliet, ... Drug metabolism and disposition 35 (11), 2006-2014, 2007 | 132 | 2007 |
Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants D Sun, G Chen, RW Dellinger, K Duncan, JL Fang, P Lazarus Breast Cancer Research 8, 1-11, 2006 | 129 | 2006 |
Updates of reactive oxygen species in melanoma etiology and progression F Liu-Smith, R Dellinger, FL Meyskens Jr Archives of biochemistry and biophysics 563, 51-55, 2014 | 123 | 2014 |
Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp> Tyr) polymorphism G Chen, AS Blevins-Primeau, RW Dellinger, JE Muscat, P Lazarus Cancer research 67 (19), 9024-9029, 2007 | 113 | 2007 |
Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform RW Dellinger, JL Fang, G Chen, R Weinberg, P Lazarus Drug metabolism and disposition 34 (6), 943-949, 2006 | 111 | 2006 |
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration S Mukherjee, K Chellappa, A Moffitt, J Ndungu, RW Dellinger, JG Davis, ... Hepatology 65 (2), 616-630, 2017 | 107 | 2017 |
Oxidative stress and antioxidants in the pathophysiology of malignant melanoma E Obrador, F Liu-Smith, RW Dellinger, R Salvador, FL Meyskens, ... Biological chemistry 400 (5), 589-612, 2019 | 106 | 2019 |
Glucuronidation of PhIP and N -OH-PhIP by UDP-glucuronosyltransferase 1A10 RW Dellinger, G Chen, AS Blevins-Primeau, J Krzeminski, S Amin, ... Carcinogenesis 28 (11), 2412-2418, 2007 | 92 | 2007 |
Differences in the glucuronidation of resveratrol and pterostilbene: altered enzyme specificity and potential gender differences RW Dellinger, AMG Garcia, FL Meyskens Jr Drug metabolism and pharmacokinetics 29 (2), 112-119, 2014 | 88 | 2014 |
Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype RM Balliet, G Chen, CJ Gallagher, RW Dellinger, D Sun, P Lazarus Cancer research 69 (7), 2981-2989, 2009 | 84 | 2009 |
Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study JÉE de la Rubia, E Drehmer, JÉL Platero, MÍ Benlloch, J Caplliure-Llopis, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (1-2), 115-122, 2019 | 83 | 2019 |
Glucuronidation of tobacco-specific nitrosamines by UGT2B10 G Chen, RW Dellinger, D Sun, TE Spratt, P Lazarus Drug metabolism and disposition 36 (5), 824-830, 2008 | 79 | 2008 |
Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics D Sun, G Chen, RW Dellinger, AK Sharma, P Lazarus Pharmacogenetics and genomics 20 (10), 575-585, 2010 | 73 | 2010 |
Human Spy1 promotes survival of mammalian cells following DNA damage EA Barnes, LA Porter, JL Lenormand, RW Dellinger, DJ Donoghue Cancer research 63 (13), 3701-3707, 2003 | 63 | 2003 |