| Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers M Soula, RA Weber, O Zilka, H Alwaseem, K La, F Yen, H Molina, ... Nature chemical biology 16 (12), 1351-1360, 2020 | 392 | 2020 |
| Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours J Garcia-Bermudez, L Baudrier, K La, XG Zhu, J Fidelin, VO Sviderskiy, ... Nature cell biology 20 (7), 775-781, 2018 | 357 | 2018 |
| Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ... Nature 567 (7746), 118-122, 2019 | 296 | 2019 |
| The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival J García-Bermúdez, JM Cuezva Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (8), 1167-1182, 2016 | 143 | 2016 |
| PKA phosphorylates the ATPase inhibitory factor 1 and inactivates its capacity to bind and inhibit the mitochondrial H+-ATP synthase J García-Bermúdez, M Sánchez-Aragó, B Soldevilla, A Del Arco, ... Cell reports 12 (12), 2143-2155, 2015 | 127 | 2015 |
| Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers M Sánchez-Aragó, L Formentini, I Martínez-Reyes, J García-Bermudez, ... Oncogenesis 2 (4), e46-e46, 2013 | 88 | 2013 |
| Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells M Sánchez‐Aragó, J García‐Bermúdez, I Martínez‐Reyes, ... EMBO reports 14 (7), 638-644, 2013 | 73 | 2013 |
| Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state F Santacatterina, L Sánchez-Cenizo, L Formentini, MA Mobasher, ... Oncotarget 7 (1), 490, 2016 | 72 | 2016 |
| Targeting extracellular nutrient dependencies of cancer cells J Garcia-Bermudez, RT Williams, R Guarecuco, K Birsoy Molecular metabolism 33, 67-82, 2020 | 63 | 2020 |
| ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase RT Williams, R Guarecuco, LA Gates, D Barrows, MC Passarelli, B Carey, ... Cell metabolism 31 (4), 852-861. e6, 2020 | 52 | 2020 |
| Target identification reveals lanosterol synthase as a vulnerability in glioma RE Phillips, Y Yang, RC Smith, BM Thompson, T Yamasaki, ... Proceedings of the National Academy of Sciences 116 (16), 7957-7962, 2019 | 50 | 2019 |
| The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing S Parsa, A Ortega-Molina, HY Ying, M Jiang, M Teater, J Wang, C Zhao, ... Nature cancer 1 (6), 653-664, 2020 | 41 | 2020 |
| A mitochondrial gatekeeper that helps cells escape death by ferroptosis J Garcia-Bermudez, K Birsoy Nature 593 (7860), 514-515, 2021 | 34 | 2021 |
| IF1 reprograms energy metabolism and signals the oncogenic phenotype in cancer M Sánchez-Aragó, L Formentini, J García-Bermúdez, JM Cuezva Cell Cycle 11 (16), 2963-2964, 2012 | 26 | 2012 |
| Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia J Garcia-Bermudez, MA Badgley, S Prasad, L Baudrier, Y Liu, K La, ... Nature Metabolism, 1-15, 2022 | 23 | 2022 |
| Drugging ACAT1 for cancer therapy J Garcia-Bermudez, K Birsoy Molecular cell 64 (5), 856-857, 2016 | 20 | 2016 |
| Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells R Guarecuco, RT Williams, L Baudrier, K La, MC Passarelli, N Ekizoglu, ... Science Advances 6 (41), eabc7120, 2020 | 12 | 2020 |
| Determination of the H+-ATP synthase and hydrolytic activities J García-Bermúdez, C Nuevo-Tapioles, JM Cuezva Bio-protocol 6 (16), e1905-e1905, 2016 | 8 | 2016 |
| Spotlight on GOT2 in Cancer Metabolism SA Kerk, J Garcia-Bermudez, K Birsoy, MH Sherman, YM Shah, ... OncoTargets and Therapy, 695-702, 2023 | 3 | 2023 |
| Electron transport inhibition increases cellular dependence on purine transport and salvage Z Wu, D Bezwada, RC Harris, C Pan, PT Nguyen, B Faubert, L Cai, F Cai, ... bioRxiv, 2023.05. 11.540429, 2023 | 2 | 2023 |
Kivanc BirsoyChapman-Perelman Associate Professor, Rockefeller UniversityVerified email at rockefeller.edu
