Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS S Adinolfi, C Iannuzzi, F Prischi, C Pastore, S Iametti, SR Martin, F Bonomi, ... Nature structural & molecular biology 16 (4), 390-396, 2009 | 313 | 2009 |
Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly F Prischi, PV Konarev, C Iannuzzi, C Pastore, S Adinolfi, SR Martin, ... Nature communications 1 (1), 95, 2010 | 202 | 2010 |
The effect of glycosaminoglycans (GAGs) on amyloid aggregation and toxicity C Iannuzzi, G Irace, I Sirangelo Molecules 20 (2), 2510-2528, 2015 | 133 | 2015 |
Differential effects of glycation on protein aggregation and amyloid formation C Iannuzzi, G Irace, I Sirangelo Frontiers in molecular biosciences 1, 9, 2014 | 120 | 2014 |
Effector role reversal during evolution: the case of frataxin in Fe–S cluster biosynthesis J Bridwell-Rabb, C Iannuzzi, A Pastore, DP Barondeau Biochemistry 51 (12), 2506-2514, 2012 | 114 | 2012 |
Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F I Sirangelo, C Malmo, C Iannuzzi, A Mezzogiorno, MR Bianco, M Papa, ... Journal of Biological Chemistry 279 (13), 13183-13189, 2004 | 96 | 2004 |
Ferredoxin competes with bacterial frataxin in binding to the desulfurase IscS R Yan, PV Konarev, C Iannuzzi, S Adinolfi, B Roche, G Kelly, L Simon, ... Journal of Biological Chemistry 288 (34), 24777-24787, 2013 | 86 | 2013 |
Insights into insulin fibril assembly at physiological and acidic pH and related amyloid intrinsic fluorescence C Iannuzzi, M Borriello, M Portaccio, G Irace, I Sirangelo International journal of molecular sciences 18 (12), 2551, 2017 | 71 | 2017 |
The role of CyaY in iron sulfur cluster assembly on the E. coli IscU scaffold protein C Iannuzzi, S Adinolfi, BD Howes, R Garcia-Serres, M Clémancey, ... PloS one 6 (7), e21992, 2011 | 68 | 2011 |
The role of metal binding in the amyotrophic lateral sclerosis-related aggregation of copper-zinc superoxide dismutase I Sirangelo, C Iannuzzi Molecules 22 (9), 1429, 2017 | 64 | 2017 |
Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate R Ferriero, C Iannuzzi, G Manco, N Brunetti-Pierri Journal of inherited metabolic disease 38, 895-904, 2015 | 57 | 2015 |
Effect of trehalose on W7FW14F apomyoglobin and insulin fibrillization: new insight into inhibition activity S Vilasi, C Iannuzzi, M Portaccio, G Irace, I Sirangelo Biochemistry 47 (6), 1789-1796, 2008 | 57 | 2008 |
Misfolding and amyloid aggregation of apomyoglobin C Iannuzzi, R Maritato, G Irace, I Sirangelo International journal of molecular sciences 14 (7), 14287-14300, 2013 | 51 | 2013 |
Vanillin affects amyloid aggregation and non-enzymatic glycation in human insulin C Iannuzzi, M Borriello, G Irace, M Cammarota, A Di Maro, I Sirangelo Scientific Reports 7 (1), 15086, 2017 | 50 | 2017 |
The role of zinc in the stability of the marginally stable IscU scaffold protein C Iannuzzi, M Adrover, R Puglisi, R Yan, PA Temussi, A Pastore Protein Science 23 (9), 1208-1219, 2014 | 49 | 2014 |
Of the vulnerability of orphan complex proteins: the case study of the E. coli IscU and IscS proteins F Prischi, C Pastore, M Carroni, C Iannuzzi, S Adinolfi, P Temussi, ... Protein expression and purification 73 (2), 161-166, 2010 | 47 | 2010 |
D-ribose-glycation of insulin prevents amyloid aggregation and produces cytotoxic adducts C Iannuzzi, M Borriello, V Carafa, L Altucci, M Vitiello, ML Balestrieri, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (1), 93-104, 2016 | 42 | 2016 |
Anatomy of an iron-sulfur cluster scaffold protein: Understanding the determinants of [2Fe–2S] cluster stability on IscU M Adrover, BD Howes, C Iannuzzi, G Smulevich, A Pastore Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (6), 1448-1456, 2015 | 42 | 2015 |
Understanding the role of protein glycation in the amyloid aggregation process I Sirangelo, C Iannuzzi International Journal of Molecular Sciences 22 (12), 6609, 2021 | 41 | 2021 |
Tetracycline inhibits W7FW14F apomyoglobin fibril extension and keeps the amyloid protein in a prefibrillar, highly cytotoxic state C Malmo, S Vilasi, C Iannuzzi, S Tacchi, C Cametti, G Irace, I Sirangelo The FASEB journal 20 (2), 346-347, 2006 | 39 | 2006 |