| Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma S Tardito, A Oudin, SU Ahmed, F Fack, O Keunen, L Zheng, H Miletic, ... Nature cell biology 17 (12), 1556-1568, 2015 | 478 | 2015 |
| Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015 | 398 | 2015 |
| Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells SU Ahmed, R Carruthers, L Gilmour, S Yildirim, C Watts, AJ Chalmers Cancer research 75 (20), 4416-4428, 2015 | 185 | 2015 |
| Small-molecule inhibitors of the MDM2-p53 protein− protein interaction based on an isoindolinone scaffold IR Hardcastle, SU Ahmed, H Atkins, G Farnie, BT Golding, RJ Griffin, ... Journal of medicinal chemistry 49 (21), 6209-6221, 2006 | 176 | 2006 |
| Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein− protein interaction: structure− activity studies leading to improved potency IR Hardcastle, J Liu, E Valeur, A Watson, SU Ahmed, TJ Blackburn, ... Journal of medicinal chemistry 54 (5), 1233-1243, 2011 | 161 | 2011 |
| JNK2-dependent regulation of SIRT1 protein stability J Ford, S Ahmed, S Allison, M Jiang, J Milner Cell Cycle 7 (19), 3091-3097, 2008 | 159 | 2008 |
| Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells RD Carruthers, SU Ahmed, S Ramachandran, K Strathdee, KM Kurian, ... Cancer research 78 (17), 5060-5071, 2018 | 147 | 2018 |
| Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase R Carruthers, SU Ahmed, K Strathdee, N Gomez-Roman, ... Molecular oncology 9 (1), 192-203, 2015 | 142 | 2015 |
| Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction IR Hardcastle, SU Ahmed, H Atkins, AH Calvert, NJ Curtin, G Farnie, ... Bioorganic & medicinal chemistry letters 15 (5), 1515-1520, 2005 | 131 | 2005 |
| SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53 CJ Lynch, ZH Shah, SJ Allison, SU Ahmed, J Ford, LJ Warnock, H Li, ... PloS one 5 (10), e13502, 2010 | 57 | 2010 |
| PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells A Kaur, OV Denisova, X Qiao, M Jumppanen, E Peuhu, SU Ahmed, ... Cancer research 76 (23), 7001-7011, 2016 | 56 | 2016 |
| Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network SU Ahmed, J Milner PLoS One 4 (10), e7305, 2009 | 45 | 2009 |
| A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes ZH Shah, SU Ahmed, JR Ford, SJ Allison, JRP Knight, J Milner Molecular and cellular biology 32 (3), 704-716, 2012 | 40 | 2012 |
| Diaryl-and triaryl-pyrrole derivatives: inhibitors of the MDM2–p53 and MDMX–p53 protein–protein interactions TJ Blackburn, S Ahmed, CR Coxon, J Liu, X Lu, BT Golding, RJ Griffin, ... MedChemComm 4 (9), 1297-1304, 2013 | 31 | 2013 |
John LunecNewcastle UniversityVerified email at ncl.ac.uk
