| Effect of dexamethasone in hospitalized patients with COVID-19–preliminary report P Horby, WS Lim, J Emberson, M Mafham, J Bell, L Linsell, N Staplin, ... MedRxiv, 2020.06. 22.20137273, 2020 | 11460* | 2020 |
| UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age C Sudlow, J Gallacher, N Allen, V Beral, P Burton, J Danesh, P Downey, ... PLoS medicine 12 (3), e1001779, 2015 | 8001 | 2015 |
| Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials CT Trialists The Lancet 376 (9753), 1670-1681, 2010 | 4265* | 2010 |
| The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo … C Baigent, MJ Landray, C Reith, J Emberson, DC Wheeler, C Tomson, ... The Lancet 377 (9784), 2181-2192, 2011 | 2927 | 2011 |
| Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis JAC Sterne, S Murthy, JV Diaz, AS Slutsky, J Villar, DC Angus, D Annane, ... Jama 324 (13), 1330-1341, 2020 | 1839 | 2020 |
| Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 1836* | 2021 |
| Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients MJ Landray, R Haynes, JC Hopewell, S Parish, T Aung, J Tomson, ... New England Journal of Medicine 371, 203-212, 2014 | 1702 | 2014 |
| Effect of hydroxychloroquine in hospitalized patients with Covid-19 RECOVERY Collaborative Group New England Journal of Medicine 383 (21), 2030-2040, 2020 | 1458 | 2020 |
| Effects of anacetrapib in patients with atherosclerotic vascular disease HPS3/TIMI55–Reveal Collaborative Group New England Journal of Medicine 377 (13), 1217-1227, 2017 | 901 | 2017 |
| Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial PW Horby, M Mafham, JL Bell, L Linsell, N Staplin, J Emberson, ... The Lancet 396 (10259), 1345-1352, 2020 | 793 | 2020 |
| Empagliflozin in patients with chronic kidney disease EMPA-Kidney Collaborative Group New England Journal of Medicine 388 (2), 117-127, 2023 | 789 | 2023 |
| HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for … R Haynes, L Jiang, JC Hopewell, J Li, F Chen, S Parish, MJ Landray, ... European heart journal 34 (17), 1279-1291, 2013 | 763 | 2013 |
| COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England MM Mafham, E Spata, R Goldacre, D Gair, P Curnow, M Bray, S Hollings, ... The Lancet 396 (10248), 381-389, 2020 | 717 | 2020 |
| Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials J Armitage, C Baigent, E Barnes, DJ Betteridge, L Blackwell, M Blazing, ... The Lancet 393 (10170), 407-415, 2019 | 663 | 2019 |
| Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group, PW Horby, M Mafham, L Peto, ... Medrxiv, 2021.06. 15.21258542, 2021 | 662* | 2021 |
| Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis CT Trialists The Lancet 371 (9607), 117-125, 2008 | 662 | 2008 |
| 2017 cardiovascular and stroke endpoint definitions for clinical trials KA Hicks, KW Mahaffey, R Mehran, SE Nissen, SD Wiviott, B Dunn, ... Circulation 137 (9), 961-972, 2018 | 619 | 2018 |
| Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial. J Armitage, L Bowman, K Wallendszus, R Bulbulia, K Rahimi, R Haynes, ... Lancet (London, England) 376 (9753), 2010 | 533 | 2010 |
| Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis P Domingo, I Mur, GM Mateo, M del Mar Gutierrez, V Pomar, N de Benito, ... Jama 326 (6), 499-518, 2021 | 470 | 2021 |
| Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study MJ Landray, DC Wheeler, GYH Lip, DJ Newman, AD Blann, FJ McGlynn, ... American journal of kidney diseases 43 (2), 244-253, 2004 | 426 | 2004 |
