Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3γ LH Wong, KG Krauer, I Hatzinisiriou, MJ Estcourt, P Hersey, ND Tam, ... Journal of Biological Chemistry 272 (45), 28779-28785, 1997 | 326 | 1997 |
The β-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism S Petratos, QX Li, AJ George, X Hou, ML Kerr, SE Unabia, I Hatzinisiriou, ... Brain 131 (1), 90-108, 2008 | 223 | 2008 |
Bcl-2 and mitochondrial oxygen radicals: new approaches with reactive oxygen species-sensitive probes M Degli Esposti, I Hatzinisiriou, H McLennan, S Ralph Journal of Biological Chemistry 274 (42), 29831-29837, 1999 | 219 | 1999 |
Rosella: a fluorescent pH-biosensor for reporting vacuolar turnover of cytosol and organelles in yeast C Rosado, D Mijaljica, I Hatzinisiriou, M Prescott, RJ Devenish Autophagy 4 (2), 205-213, 2008 | 143 | 2008 |
Isolation and Characterization of a Human STAT1Gene Regulatory Element: INDUCIBILITY BY INTERFERON (IFN) TYPES I AND II AND ROLE OF IFN REGULATORY FACTOR-1 LH Wong, H Sim, M Chatterjee-Kishore, I Hatzinisiriou, RJ Devenish, ... Journal of Biological Chemistry 277 (22), 19408-19417, 2002 | 119 | 2002 |
Leukemia inhibitory factor arrests oligodendrocyte death and demyelination in spinal cord injury MF Azari, C Profyris, T Karnezis, CC Bernard, DH Small, SS Cheema, ... Journal of Neuropathology & Experimental Neurology 65 (9), 914-929, 2006 | 97 | 2006 |
IFN-γ priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs LH Wong, I Hatzinisiriou, RJ Devenish, SJ Ralph The Journal of Immunology 160 (11), 5475-5484, 1998 | 78 | 1998 |
Resistance of melanoma cell lines to interferons correlates with reduction of IFN-induced tyrosine phosphorylation. Induction of the anti-viral state by IFN is prevented by … SJ Ralph, BD Wines, MJ Payne, D Grubb, I Hatzinisiriou, AW Linnane, ... Journal of immunology (Baltimore, Md.: 1950) 154 (5), 2248-2256, 1995 | 40 | 1995 |
Enhancing CTL responses to melanoma cell vaccines in vivo: synergistic increases obtained using IFNγ primed and IFNβ treated B7‐1+ B16‐F10 melanoma cells S Dezfouli, I Hatzinisiriou, SJ Ralph Immunology and cell biology 81 (6), 459-471, 2003 | 32 | 2003 |
Use of cytokines in cancer vaccines/immunotherapy: recent developments improve survival rates for patients with metastatic malignancy S Dezfouli, I Hatzinisiriou, SJ Ralph Current pharmaceutical design 11 (27), 3511-3530, 2005 | 22 | 2005 |
Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines DJ Smith, LR Cossins, I Hatzinisiriou, M Haber, P Nagley BMC cancer 8, 1-8, 2008 | 21 | 2008 |
SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis DL Cottle, MJ McGrath, BR Wilding, BS Cowling, JM Kane, CE D'Arcy, ... Journal of biological chemistry 284 (39), 26964-26977, 2009 | 20 | 2009 |
A colourimetric dye assay to detect anti-viral activity of interferons: sensitivity for measuring cellular responsiveness to interferons. BD Wines, CC Choe, I Hatzinisiriou, RJ Devenish, AW Linnane, SJ Ralph Biochemistry and molecular biology international 31 (6), 1111-1120, 1993 | 7 | 1993 |
Revising interferons-prodigies among the cytokines SJ Ralph, LH Wong, I Hatzinisiriou, M Estcourt, P Hersey, RJ Devenish Today's Life Science 10 (10), 37-43, 1998 | 3 | 1998 |
Research Article Enhancing CTL responses to melanoma cell vaccines in vivo: synergistic increases obtained using IFNγ primed and IFNβ treated B7-1+ B16-F10 … S Dezfouli, I Hatzinisiriou, SJ Ralph Immunology & Cell Biology 81 (6), 2003 | | 2003 |
GENES: STRUCTURE AND REGULATION-Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN … LH Wong, H Sim, M Chatterjee-Kishore, I Hatzinisiriou, RJ Devenish, ... Journal of Biological Chemistry 277 (22), 19408-19417, 2002 | | 2002 |
Immunology: Interferons are back in the spotlight as we understand more about their cellular actions and use them to achieve greater patient benefits S Ralph, I Hatzinisiriou, M Estcourt, P Hersey, R Devenish TODAYS LIFE SCIENCE 10, 37-43, 1998 | | 1998 |
Deficiency of transcription factor ISGF3 and IRF1 proteins in interferon-resistant melanoma cells: a mechanism of interferon signalling defect LH Wong, I Hatzinisiriou, P Hersey, N Tam, S Edmondson, RJ Devenish, ... Lorne Cancer Conference 1997, 1997 | | 1997 |
Deficiency of transcription factor ISGF3 in interferon-resistant melanoma cells: a mechanism of interferon signalling defect LH Wong, K Krauer, M Estcourt, I Hatzinisiriou, P Hersey, N Tam, ... 41st Ann. ASBMB and 37th Ann. ASPP Conferences, 1997 | | 1997 |
Deficiency of interferon regulated transcription factors, ISGF3 and IRF1 in interferon resistant melanoma cells: restoring cell responsiveness by gene therapy LH Wong, I Hatzinisiriou, P Hersey, N Tam, S Edmondson, RJ Devenish, ... 1997 Ann. Meeting of the Interferon Society for Interferon & Cytokine Research, 1997 | | 1997 |