Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice T Hendrikx, YI Duan, Y Wang, JH Oh, LM Alexander, W Huang, P Stärkel, ... Gut 68 (8), 1504-1515, 2019 | 229 | 2019 |
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease V Bieghs, PJ Van Gorp, K Wouters, T Hendrikx, MJ Gijbels, M van Bilsen, ... PloS one 7 (1), e30668, 2012 | 197 | 2012 |
Indoles: metabolites produced by intestinal bacteria capable of controlling liver disease manifestation T Hendrikx, B Schnabl Journal of internal medicine 286 (1), 32-40, 2019 | 142 | 2019 |
Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2 S Jäckel, K Kiouptsi, M Lillich, T Hendrikx, A Khandagale, B Kollar, ... Blood, The Journal of the American Society of Hematology 130 (4), 542-553, 2017 | 131 | 2017 |
Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells V Bieghs, F Verheyen, PJ van Gorp, T Hendrikx, K Wouters, D Lütjohann, ... PloS one 7 (3), e34378, 2012 | 131 | 2012 |
Trapping of oxidized LDL in lysosomes of K upffer cells is a trigger for hepatic inflammation V Bieghs, SMA Walenbergh, T Hendrikx, PJ van Gorp, F Verheyen, ... Liver International 33 (7), 1056-1061, 2013 | 101 | 2013 |
The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice V Bieghs, T Hendrikx, PJ van Gorp, F Verheyen, YD Guichot, ... Gastroenterology 144 (1), 167-178. e1, 2013 | 101 | 2013 |
Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells Y Wang, S van der Tuin, N Tjeerdema, AD van Dam, SS Rensen, ... Hepatology 62 (6), 1710-1722, 2015 | 87 | 2015 |
Lysosomal cholesterol accumulation: driver on the road to inflammation during atherosclerosis and non‐alcoholic steatohepatitis T Hendrikx, SMA Walenbergh, MH Hofker, R Shiri‐Sverdlov obesity reviews 15 (5), 424-433, 2014 | 84 | 2014 |
Sialic acid-binding immunoglobulin-like lectin G promotes atherosclerosis and liver inflammation by suppressing the protective functions of B-1 cells S Gruber, T Hendrikx, D Tsiantoulas, M Ozsvar-Kozma, L Göderle, ... Cell reports 14 (10), 2348-2361, 2016 | 74 | 2016 |
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH T Hendrikx, F Porsch, MG Kiss, D Rajcic, N Papac-Miličević, C Hoebinger, ... Journal of hepatology 77 (5), 1373-1385, 2022 | 72 | 2022 |
Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice T Hendrikx, MLJ Jeurissen, PJ van Gorp, MJ Gijbels, SMA Walenbergh, ... The FEBS journal 282 (12), 2327-2338, 2015 | 72 | 2015 |
Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice CJL Busch, T Hendrikx, D Weismann, S Jäckel, SMA Walenbergh, ... Hepatology 65 (4), 1181-1195, 2017 | 65 | 2017 |
Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans J Plat, T Hendrikx, V Bieghs, MLJ Jeurissen, SMA Walenbergh, ... PloS one 9 (10), e110758, 2014 | 61 | 2014 |
Cathepsin D regulates lipid metabolism in murine steatohepatitis T Houben, Y Oligschlaeger, T Hendrikx, AV Bitorina, SMA Walenbergh, ... Scientific reports 7 (1), 3494, 2017 | 52 | 2017 |
Plasma cathepsin D levels: a novel tool to predict pediatric hepatic inflammation SMA Walenbergh, T Houben, T Hendrikx, MLJ Jeurissen, PJ Van Gorp, ... Official journal of the American College of Gastroenterology| ACG 110 (3 …, 2015 | 49 | 2015 |
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice T Hendrikx, V Bieghs, SMA Walenbergh, PJ van Gorp, F Verheyen, ... PLoS One 8 (12), e78792, 2013 | 46 | 2013 |
Antimicrobial proteins: intestinal guards to protect against liver disease T Hendrikx, B Schnabl Journal of gastroenterology 54, 209-217, 2019 | 43 | 2019 |
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans D Tsiantoulas, M Eslami, G Obermayer, M Clement, D Smeets, FJ Mayer, ... Nature 597 (7874), 92-96, 2021 | 42 | 2021 |
Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention SMA Walenbergh, T Houben, SS Rensen, V Bieghs, T Hendrikx, ... Scientific reports 6 (1), 38278, 2016 | 42 | 2016 |