From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks J Li, AS Grillo, MD Burke Accounts of chemical research 48 (8), 2297-2307, 2015 | 182 | 2015 |
Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals AS Grillo, AM SantaMaria, MD Kafina, AG Cioffi, NC Huston, M Han, ... Science 356 (6338), 608-616, 2017 | 138 | 2017 |
Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia KA Muraglia, RS Chorghade, BR Kim, XX Tang, VS Shah, AS Grillo, ... Nature 567 (7748), 405-408, 2019 | 92 | 2019 |
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity YY Yien, J Shi, C Chen, JTM Cheung, AS Grillo, R Shrestha, L Li, X Zhang, ... Journal of Biological Chemistry 293 (51), 19797-19811, 2018 | 38 | 2018 |
Restored physiology in protein-deficient yeast by a small molecule channel AG Cioffi, J Hou, AS Grillo, KA Diaz, MD Burke Journal of the American Chemical Society 137 (32), 10096-10099, 2015 | 35 | 2015 |
PKC downregulation upon rapamycin treatment attenuates mitochondrial disease M Martin-Perez*, AS Grillo*, TK Ito*, AS Valente, J Han, SW Entwisle, ... Nature Metabolism 2 (12), 1472-1481, 2020 | 30 | 2020 |
The NDUFS4 Knockout Mouse: A Dual Threat Model of Childhood Mitochondrial Disease and Normative Aging AS Grillo, A Bitto, M Kaeberlein Methods in Molecular Biology 2277, 143-155, 2021 | 10 | 2021 |
Iron status influences mitochondrial disease progression in Complex I-deficient mice CJ Kelly, RK Couch, VT Ha, CM Bodart, J Wu, S Huff, NT Herrel, HD Kim, ... Elife 12, e75825, 2023 | 7 | 2023 |
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome A Bitto, AS Grillo, IB Stanaway, BMG Nguyen, K Ying, H Tung, K Smith, ... BioRxiv 478591, 2022 | 7 | 2022 |
Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin M Martin-Perez, TK Ito, AS Grillo, AS Valente, J Han, S Entwisle, ... bioRxiv, 562207, 2019 | 5 | 2019 |
Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice AS Grillo, CJ Kelly, VT Ha, CB Bodart, S Huff, RK Couch, NT Herrel, ... BioRXiv 462431, 2021 | 3 | 2021 |
Restoring physiology in iron-deficient organisms using small molecules MD Burke, AS Grillo US Patent 11,517,540, 2022 | | 2022 |
Restoring physiology with small molecule mimics of missing proteins MD Burke, AG Cioffi, J Hou, AS GRILLO | | 2016 |