Reactive metabolites: current and emerging risk and hazard assessments RA Thompson, EM Isin, MO Ogese, JT Mettetal, DP Williams Chemical Research in Toxicology 29 (4), 505-533, 2016 | 154 | 2016 |
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses A Ogbe, B Kronsteiner, DT Skelly, M Pace, A Brown, E Adland, K Adair, ... Nature communications 12 (1), 2055, 2021 | 114 | 2021 |
Characterization of amoxicillin‐and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury SH Kim, K Saide, J Farrell, L Faulkner, A Tailor, M Ogese, AK Daly, ... Hepatology 62 (3), 887-899, 2015 | 109 | 2015 |
Negative regulation by PD-L1 during drug-specific priming of IL-22–secreting T cells and the influence of PD-1 on effector T cell function A Gibson, M Ogese, A Sullivan, E Wang, K Saide, P Whitaker, D Peckham, ... The Journal of Immunology 192 (6), 2611-2621, 2014 | 70 | 2014 |
The effect of inhibitory signals on the priming of drug hapten–specific T cells that express distinct Vβ receptors A Gibson, L Faulkner, M Lichtenfels, M Ogese, Z Al-Attar, A Alfirevic, ... The Journal of Immunology 199 (4), 1223-1237, 2017 | 52 | 2017 |
HLA restriction of carbamazepine-specific T-Cell clones from an HLA-A* 31: 01-positive hypersensitive patient M Lichtenfels, J Farrell, MO Ogese, CC Bell, S Eckle, J McCluskey, ... Chemical research in toxicology 27 (2), 175-177, 2014 | 52 | 2014 |
Dapsone‐and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B* 13: 01 Q Zhao, K Alhilali, A Alzahrani, M Almutairi, J Amjad, H Liu, Y Sun, L Sun, ... Allergy 74 (8), 1533-1548, 2019 | 45 | 2019 |
Exosomal transport of hepatocyte‐derived drug‐modified proteins to the immune system MO Ogese, RE Jenkins, K Adair, A Tailor, X Meng, L Faulkner, ... Hepatology 70 (5), 1732-1749, 2019 | 44 | 2019 |
Characterization of drug-specific signaling between primary human hepatocytes and immune cells MO Ogese, L Faulkner, RE Jenkins, NS French, IM Copple, DJ Antoine, ... Toxicological Sciences 158 (1), 76-89, 2017 | 41 | 2017 |
Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury: Industry-led perspective from EFPIA members of the EU … RJ Weaver, C Betts, EAG Blomme, HHJ Gerets, K Gjervig Jensen, ... Expert opinion on drug metabolism & toxicology 13 (7), 767-782, 2017 | 37 | 2017 |
Immune dysregulation increases the incidence of delayed‐type drug hypersensitivity reactions DJ Naisbitt, A Olsson‐Brown, A Gibson, X Meng, MO Ogese, A Tailor, ... Allergy 75 (4), 781-797, 2020 | 31 | 2020 |
Dapsone and nitroso dapsone activation of naı̈ve T-cells from healthy donors A Alzahrani, M Ogese, X Meng, JC Waddington, A Tailor, J Farrell, ... Chemical research in toxicology 30 (12), 2174-2186, 2017 | 30 | 2017 |
In vitro diagnosis of delayed-type drug hypersensitivity: mechanistic aspects and unmet needs DJ Naisbitt, RG Nattrass, MO Ogese Immunology and Allergy Clinics 34 (3), 691-705, 2014 | 30 | 2014 |
Characterization of peroxidases expressed in human antigen presenting cells and analysis of the covalent binding of nitroso sulfamethoxazole to myeloperoxidase MO Ogese, RE Jenkins, JL Maggs, X Meng, P Whitaker, D Peckham, ... Chemical Research in Toxicology 28 (1), 144-154, 2015 | 29 | 2015 |
New approaches to investigate drug-induced hypersensitivity MO Ogese, S Ahmed, A Alferivic, CJ Betts, A Dickinson, L Faulkner, ... Chemical research in toxicology 30 (1), 239-259, 2017 | 22 | 2017 |
HLA Class-II‒Restricted CD8+ T cells contribute to the promiscuous immune response in dapsone-hypersensitive patients Q Zhao, M Almutairi, A Tailor, A Lister, N Harper, J Line, X Meng, ... Journal of Investigative Dermatology 141 (10), 2412-2425. e2, 2021 | 19 | 2021 |
HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis MO Ogese, K Saide, L Faulkner, P Whitaker, D Peckham, A Alfirevic, ... Clinical & Experimental Allergy 45 (8), 1305-1316, 2015 | 19 | 2015 |
Development of an improved T-cell assay to assess the intrinsic immunogenicity of haptenic compounds MO Ogese, J Watkinson, A Lister, L Faulkner, A Gibson, A Hillegas, ... Toxicological Sciences 175 (2), 266-278, 2020 | 18 | 2020 |
T-cell activation by low molecular weight drugs and factors that influence susceptibility to drug hypersensitivity S Hammond, PJ Thomson, MO Ogese, DJ Naisbitt Chemical Research in Toxicology 33 (1), 77-94, 2019 | 16 | 2019 |
Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01 MO Ogese, A Lister, J Gardner, X Meng, A Alfirevic, M Pirmohamed, ... Toxicological Sciences 183 (1), 139-153, 2021 | 15 | 2021 |