A new approach for studying GPCR dimers: drug-induced inactivation and reactivation to reveal GPCR dimer function in vitro, in primary culture, and in vivo M Teitler, MT Klein Pharmacology & therapeutics 133 (2), 205-217, 2012 | 54 | 2012 |
Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-hydroxytryptamine7 receptor by risperidone, 9-OH-risperidone, and other inactivating … JA Knight, C Smith, N Toohey, MT Klein, M Teitler Molecular pharmacology 75 (2), 374-380, 2009 | 48 | 2009 |
Distribution of 5‐ht1E receptors in the mammalian brain and cerebral vasculature: an immunohistochemical and pharmacological study MT Klein, M Teitler British journal of pharmacology 166 (4), 1290-1302, 2012 | 46 | 2012 |
Targeting selective activation of M1 for the treatment of Alzheimer’s disease: further chemical optimization and pharmacological characterization of the M1 positive allosteric … JC Tarr, ML Turlington, PR Reid, TJ Utley, DJ Sheffler, HP Cho, R Klar, ... ACS Chemical Neuroscience 3 (11), 884-895, 2012 | 45 | 2012 |
Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR … M Teitler, N Toohey, JA Knight, MT Klein, C Smith Psychopharmacology 212, 687-697, 2010 | 39 | 2010 |
Approaches for probing allosteric interactions at 7 transmembrane spanning receptors MT Klein, PN Vinson, CM Niswender Progress in molecular biology and translational science 115, 1-59, 2013 | 27 | 2013 |
Risperidone-induced inactivation and clozapine-induced reactivation of rat cortical astrocyte 5-hydroxytryptamine7 receptors: evidence for in situ G protein-coupled receptor … C Smith, N Toohey, JA Knight, MT Klein, M Teitler Molecular Pharmacology 79 (2), 318-325, 2011 | 27 | 2011 |
Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships MT Klein, M Dukat, RA Glennon, M Teitler Journal of Pharmacology and Experimental Therapeutics 337 (3), 860-867, 2011 | 22 | 2011 |
Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other “inactivating antagonists” N Toohey, MT Klein, J Knight, C Smith, M Teitler Molecular pharmacology 76 (3), 552-559, 2009 | 22 | 2009 |
Guinea pig hippocampal 5‐HT1E receptors: a tool for selective drug development MT Klein, M Teitler Journal of neurochemistry 109 (1), 268-274, 2009 | 13 | 2009 |
Antagonist interaction with the human 5‐HT7 receptor mediates the rapid and potent inhibition of non‐G‐protein‐stimulated adenylate cyclase activity: a novel … MT Klein, M Teitler British journal of pharmacology 162 (8), 1843-1854, 2011 | 11 | 2011 |
Improving the quality of post-anesthesia care: An evidence based initiative to decrease the incidence of postoperative nausea and vomiting in the post-anesthesia care unit CA Smith, RE Haas, JC Zepp, M Klein Perioperative Care and Operating Room Management 4, 12-16, 2016 | 7 | 2016 |
Towards selective drug development for the human 5-HT1E receptor: a comparison of 5-HT1E and 5-HT1F receptor structure-affinity relationships MT Klein, M Dukat, RA Glennon, M Teitler Journal of Pharmacology and Experimental Therapeutics, 2011 | 2 | 2011 |
International Union of Basic and Clinical Pharmacology. XXX: Classification of receptors for 5-hydroxytryptamine; pharmacology and function GJ Sanger, NM Barnes, GP Ahern, C Becamel, J Bockaert, M Camilleri, ... Pharmacological Reviews, 2020 | | 2020 |
Novel Positive Allosteric Modulators Bias Acetylcholine Signaling at Human M4 Muscarinic Receptors MT Klein, G Digby, C Niswender, C Tarr, M Poslusney, B Melancon, ... The FASEB Journal 27, 1171.4-1171.4, 2013 | | 2013 |
Methylecgonidine: more than a crack cocaine biomarker RCT Garcia, LMM Dati, LHL Torres, JL Costa, M Yonamine, JC Florio, ... Abstracts, 2013 | | 2013 |
The Pharmacology and Distribution of Serotonin 5-HT-1E Receptors in the Mammalian Brain & Drug Development for the Human 5-HT-1E Receptor MT Klein Albany Medical College, 2011 | | 2011 |
Pharmacological analysis of the novel, rapid and potent inactivation of the human 5-HT7 receptor by risperidone, 9-OH-risperidone and other" inactivating antagonists" JA Knight, C Smith, N Toohey, MT Klein, M Teitler Molecular Pharmacology, 2008 | | 2008 |
Guinea pig hippocampal 5‐HT1E receptors: a tool for selective drug development MT Klein, C Smith, N Toohey, M Teitler The FASEB Journal 22, 720.8-720.8, 2008 | | 2008 |