GABAergic neuron deficit as an idiopathic generalized epilepsy mechanism: the role of BRD2 haploinsufficiency in juvenile myoclonic epilepsy L Velíšek, E Shang, J Velíšková, T Chachua, S Macchiarulo, ... PLoS One 6 (8), e23656, 2011 | 111 | 2011 |
Suppression of limbic motor seizures by electrical stimulation in thalamic reticular nucleus Z Nanobashvili, T Chachua, A Nanobashvili, I Bilanishvili, O Lindvall, ... Experimental Neurology 181 (2), 224-230, 2003 | 82 | 2003 |
Validation of the rat model of cryptogenic infantile spasms T Chachua, MS Yum, J Velíšková, L Velíšek Epilepsia 52 (9), 1666-1677, 2011 | 79 | 2011 |
Prenatal stress promotes development of spasms in infant rats MS Yum, T Chachua, J Velíšková, L Velíšek Epilepsia 53 (3), e46-e49, 2012 | 60 | 2012 |
Model of cryptogenic infantile spasms after prenatal corticosteroid priming L Velíšek, T Chachua, MS Yum, KL Poon, J Velíšková Epilepsia 51, 145-149, 2010 | 35 | 2010 |
Prenatal Corticosteroids Modify Glutamatergic and GABA ergic Synapse Genomic Fabric: Insights from a Novel Animal Model of Infantile Spasms DA Iacobas, S Iacobas, T Chachua, C Goletiani, G Sidyelyeva, ... Journal of neuroendocrinology 25 (11), 964-979, 2013 | 30 | 2013 |
Anti-seizure medications and estradiol for neuroprotection in epilepsy: the 2013 update L Velisek, N Nebieridze, T Chachua, J Veliskova Recent Patents on CNS Drug Discovery (Discontinued) 8 (1), 24-41, 2013 | 28 | 2013 |
ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms DA Iacobaş, T Chachua, S Iacobaş, MJ Benson, K Borges, J Velíšková, ... Scientific Reports 8 (1), 5722, 2018 | 27 | 2018 |
Rapamycin has age‐, treatment paradigm‐, and model‐specific anticonvulsant effects and modulates neuropeptide Y expression in rats T Chachua, KL Poon, MS Yum, L Nesheiwat, K DeSantis, J Velíšková, ... Epilepsia 53 (11), 2015-2025, 2012 | 27 | 2012 |
Sex‐specific behavioral traits in the Brd2 mouse model of juvenile myoclonic epilepsy T Chachua, C Goletiani, G Maglakelidze, G Sidyelyeva, M Daniel, ... Genes, Brain and Behavior 13 (7), 702-712, 2014 | 26 | 2014 |
Oestradiol regulates neuropeptide Y release and gene coupling with the GABAergic and glutamatergic synapses in the adult female rat dentate gyrus J Velíšková, D Iacobas, S Iacobas, G Sidyelyeva, T Chachua, L Velíšek Journal of neuroendocrinology 27 (12), 911-920, 2015 | 21 | 2015 |
Estradiol does not affect spasms in the betamethasone‐NMDA rat model of infantile spasms T Chachua, P Di Grazia, CR Chern, M Johnkutty, B Hellman, HA Lau, ... Epilepsia 57 (8), 1326-1336, 2016 | 20 | 2016 |
β-Estradiol unmasks metabotropic receptor-mediated metaplasticity of NMDA receptor transmission in the female rat dentate gyrus N Nebieridze, X Zhang, T Chachua, L Velíšek, PK Stanton, J Velíšková Psychoneuroendocrinology 37 (11), 1845-1854, 2012 | 15 | 2012 |
Noradrenergic modulation of seizure activity T Chachua, I Bilanishvili, N Khizanishvili, Z Nanobashvili Georgian Med News 6 (183), 34-39, 2010 | 14 | 2010 |
A team science approach to discover novel targets for infantile spasms (IS) CURE Infantile Spasms Consortium, CURE Staff, L Lubbers, SS Iyengar, ... Epilepsia open 6 (1), 49-61, 2021 | 8 | 2021 |
Peculiarities of the effects of stimulation of emotiogenic central structures under conditions of a kindling model of epilepsy ZI Nanobashvili, TR Chachua, IG Bilanishvili, NA Khizanishvili, ... Neurophysiology 43, 292-298, 2011 | 6 | 2011 |
A possible mechanism of blocking of limbic motor seizure reactions induced by activation of the thalamic reticular nucleus ZI Nanobashvili, TR Chachua, IG Bilanishvili, GG Beradze, TR Gotsadze, ... Neurophysiology 37, 308-316, 2005 | 3 | 2005 |
Epileptic spasms in infancy: Transferring rat prenatal betamethasone-postnatal NMDA model to mice T Chachua, CR Chern, J Velíšková, L Velíšek Neuroscience Letters 813, 137431, 2023 | 1 | 2023 |
Development of audiogenic kindling during the gestation period NT Samseishvili, IG Bilanishvili, TR Chachua, BD Tkeshelashvili Georgian Medical News, 96-98, 2006 | 1 | 2006 |
Different route of administration for melanocortin receptor agonist, melanotan II, in the model of cryptogenic infantile spasms Y Schoor, L Velisek, T Chachua, J Veliskova ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |