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Ku-Lung (Ken) Hsu
Ku-Lung (Ken) Hsu
Associate Professor of Chemistry, University of Texas at Austin
Verified email at austin.utexas.edu - Homepage
Title
Cited by
Cited by
Year
Analyzing the dynamic bacterial glycome with a lectin microarray approach
KL Hsu, KT Pilobello, LK Mahal
Nature chemical biology 2 (3), 153-157, 2006
2952006
Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors
A Adibekian, BR Martin, C Wang, KL Hsu, DA Bachovchin, S Niessen, ...
Nature chemical biology 7 (7), 469-478, 2011
2822011
DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses
KL Hsu, K Tsuboi, A Adibekian, H Pugh, K Masuda, BF Cravatt
Nature chemical biology 8 (12), 999-1007, 2012
2672012
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase
JM Inloes, KL Hsu, MM Dix, A Viader, K Masuda, T Takei, MR Wood, ...
Proceedings of the National Academy of Sciences 111 (41), 14924-14929, 2014
1722014
Global targeting of functional tyrosines using sulfur-triazole exchange chemistry
HS Hahm, EK Toroitich, AL Borne, JW Brulet, AH Libby, K Yuan, TB Ware, ...
Nature chemical biology 16 (2), 150-159, 2020
1572020
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
A Adibekian, BR Martin, JW Chang, KL Hsu, K Tsuboi, DA Bachovchin, ...
Journal of the American Chemical Society 134 (25), 10345-10348, 2012
1452012
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes
E Dominguez, A Galmozzi, JW Chang, KL Hsu, J Pawlak, W Li, C Godio, ...
Nature chemical biology 10 (2), 113-121, 2014
1442014
A lectin microarray approach for the rapid analysis of bacterial glycans
KL Hsu, LK Mahal
Nature protocols 1 (2), 543-549, 2006
1372006
ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice
AV Naydenov, EA Horne, CS Cheah, K Swinney, KL Hsu, JK Cao, ...
Neuron 83 (2), 361-371, 2014
1252014
Discovery and optimization of piperidyl-1, 2, 3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)
KL Hsu, K Tsuboi, JW Chang, LR Whitby, AE Speers, H Pugh, BF Cravatt
Journal of medicinal chemistry 56 (21), 8270-8279, 2013
1022013
Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons
MP Baggelaar, PJP Chameau, V Kantae, J Hummel, KL Hsu, F Janssen, ...
Journal of the American Chemical Society 137 (27), 8851-8857, 2015
942015
Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode
P Agrawal, T Kurcon, KT Pilobello, JF Rakus, S Koppolu, Z Liu, BS Batista, ...
Proceedings of the National Academy of Sciences 111 (11), 4338-4343, 2014
932014
A simple strategy for the creation of a recombinant lectin microarray
KL Hsu, JC Gildersleeve, LK Mahal
Molecular BioSystems 4 (6), 654-662, 2008
932008
Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy
ZA Curry, JL Wilkerson, D Bagdas, SL Kyte, N Patel, G Donvito, ...
Journal of Pharmacology and Experimental Therapeutics 366 (1), 169-183, 2018
782018
Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer
RA Kohnz, MM Mulvihill, JW Chang, KL Hsu, A Sorrentino, BF Cravatt, ...
ACS chemical biology 10 (7), 1624-1630, 2015
722015
Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition
AM Zuhl, JT Mohr, DA Bachovchin, S Niessen, KL Hsu, JM Berlin, ...
Journal of the American Chemical Society 134 (11), 5068-5071, 2012
682012
Liganding functional tyrosine sites on proteins using sulfur–triazole exchange chemistry
JW Brulet, AL Borne, K Yuan, AH Libby, KL Hsu
Journal of the American Chemical Society 142 (18), 8270-8280, 2020
662020
Development and optimization of piperidyl-1, 2, 3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis
KL Hsu, K Tsuboi, LR Whitby, AE Speers, H Pugh, J Inloes, BF Cravatt
Journal of medicinal chemistry 56 (21), 8257-8269, 2013
632013
Sweet tasting chips: microarray-based analysis of glycans
KL Hsu, LK Mahal
Current opinion in chemical biology 13 (4), 427-432, 2009
592009
Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models
TW Grim, S Ghosh, KL Hsu, BF Cravatt, SG Kinsey, AH Lichtman
Pharmacology Biochemistry and Behavior 124, 405-411, 2014
552014
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