Analyzing the dynamic bacterial glycome with a lectin microarray approach KL Hsu, KT Pilobello, LK Mahal Nature chemical biology 2 (3), 153-157, 2006 | 295 | 2006 |
Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors A Adibekian, BR Martin, C Wang, KL Hsu, DA Bachovchin, S Niessen, ... Nature chemical biology 7 (7), 469-478, 2011 | 282 | 2011 |
DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses KL Hsu, K Tsuboi, A Adibekian, H Pugh, K Masuda, BF Cravatt Nature chemical biology 8 (12), 999-1007, 2012 | 267 | 2012 |
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase JM Inloes, KL Hsu, MM Dix, A Viader, K Masuda, T Takei, MR Wood, ... Proceedings of the National Academy of Sciences 111 (41), 14924-14929, 2014 | 172 | 2014 |
Global targeting of functional tyrosines using sulfur-triazole exchange chemistry HS Hahm, EK Toroitich, AL Borne, JW Brulet, AH Libby, K Yuan, TB Ware, ... Nature chemical biology 16 (2), 150-159, 2020 | 157 | 2020 |
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes A Adibekian, BR Martin, JW Chang, KL Hsu, K Tsuboi, DA Bachovchin, ... Journal of the American Chemical Society 134 (25), 10345-10348, 2012 | 145 | 2012 |
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes E Dominguez, A Galmozzi, JW Chang, KL Hsu, J Pawlak, W Li, C Godio, ... Nature chemical biology 10 (2), 113-121, 2014 | 144 | 2014 |
A lectin microarray approach for the rapid analysis of bacterial glycans KL Hsu, LK Mahal Nature protocols 1 (2), 543-549, 2006 | 137 | 2006 |
ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice AV Naydenov, EA Horne, CS Cheah, K Swinney, KL Hsu, JK Cao, ... Neuron 83 (2), 361-371, 2014 | 125 | 2014 |
Discovery and optimization of piperidyl-1, 2, 3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6) KL Hsu, K Tsuboi, JW Chang, LR Whitby, AE Speers, H Pugh, BF Cravatt Journal of medicinal chemistry 56 (21), 8270-8279, 2013 | 102 | 2013 |
Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons MP Baggelaar, PJP Chameau, V Kantae, J Hummel, KL Hsu, F Janssen, ... Journal of the American Chemical Society 137 (27), 8851-8857, 2015 | 94 | 2015 |
Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode P Agrawal, T Kurcon, KT Pilobello, JF Rakus, S Koppolu, Z Liu, BS Batista, ... Proceedings of the National Academy of Sciences 111 (11), 4338-4343, 2014 | 93 | 2014 |
A simple strategy for the creation of a recombinant lectin microarray KL Hsu, JC Gildersleeve, LK Mahal Molecular BioSystems 4 (6), 654-662, 2008 | 93 | 2008 |
Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy ZA Curry, JL Wilkerson, D Bagdas, SL Kyte, N Patel, G Donvito, ... Journal of Pharmacology and Experimental Therapeutics 366 (1), 169-183, 2018 | 78 | 2018 |
Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer RA Kohnz, MM Mulvihill, JW Chang, KL Hsu, A Sorrentino, BF Cravatt, ... ACS chemical biology 10 (7), 1624-1630, 2015 | 72 | 2015 |
Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition AM Zuhl, JT Mohr, DA Bachovchin, S Niessen, KL Hsu, JM Berlin, ... Journal of the American Chemical Society 134 (11), 5068-5071, 2012 | 68 | 2012 |
Liganding functional tyrosine sites on proteins using sulfur–triazole exchange chemistry JW Brulet, AL Borne, K Yuan, AH Libby, KL Hsu Journal of the American Chemical Society 142 (18), 8270-8280, 2020 | 66 | 2020 |
Development and optimization of piperidyl-1, 2, 3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis KL Hsu, K Tsuboi, LR Whitby, AE Speers, H Pugh, J Inloes, BF Cravatt Journal of medicinal chemistry 56 (21), 8257-8269, 2013 | 63 | 2013 |
Sweet tasting chips: microarray-based analysis of glycans KL Hsu, LK Mahal Current opinion in chemical biology 13 (4), 427-432, 2009 | 59 | 2009 |
Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models TW Grim, S Ghosh, KL Hsu, BF Cravatt, SG Kinsey, AH Lichtman Pharmacology Biochemistry and Behavior 124, 405-411, 2014 | 55 | 2014 |