Pharmacological targeting of IRE1 in cancer DP Raymundo, D Doultsinos, X Guillory, A Carlesso, LA Eriksson, ... Trends in cancer 6 (12), 1018-1030, 2020 | 70 | 2020 |
Design polysaccharides of marine origin: chemical modifications to reach advanced versatile compounds N Chopin, X Guillory, P Weiss, JL Bideau, S Colliec-Jouault Current Organic Chemistry 18 (7), 867-895, 2014 | 58 | 2014 |
The molecular tweezer CLR01 stabilizes a disordered protein–protein interface D Bier, S Mittal, K Bravo-Rodriguez, A Sowislok, X Guillory, J Briels, ... Journal of the American Chemical Society 139 (45), 16256-16263, 2017 | 57 | 2017 |
Fragment-based differential targeting of PPI stabilizer interfaces X Guillory, M Wolter, S Leysen, JF Neves, A Kuusk, S Genet, B Somsen, ... Journal of medicinal chemistry 63 (13), 6694-6707, 2020 | 36 | 2020 |
Glycidyl alkoxysilane reactivities towards simple nucleophiles in organic media for improved molecular structure definition in hybrid materials X Guillory, A Tessier, GO Gratien, P Weiss, S Colliec-Jouault, D Dubreuil, ... RSC advances 6 (78), 74087-74099, 2016 | 24 | 2016 |
Structural and molecular bases to IRE1 activity modulation T Langlais, D Pelizzari-Raymundo, SJ Mahdizadeh, N Gouault, ... Biochemical Journal 478 (15), 2953-2975, 2021 | 10 | 2021 |
Mono‐and Bivalent 14‐3‐3 Inhibitors for Characterizing Supramolecular “Lysine Wrapping” of Oligoethylene Glycol (OEG) Moieties in Proteins E Yilmaz, D Bier, X Guillory, J Briels, YB Ruiz‐Blanco, E Sanchez‐Garcia, ... Chemistry–A European Journal 24 (52), 13807-13814, 2018 | 10 | 2018 |
Supramolecular enhancement of a natural 14–3–3 protein ligand X Guillory, I Hadrovic, PJ de Vink, A Sowislok, L Brunsveld, T Schrader, ... Journal of the American Chemical Society 143 (34), 13495-13500, 2021 | 9 | 2021 |
A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ... Iscience 26 (5), 2023 | 6 | 2023 |
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking EJ Visser, P Jaishankar, E Sijbesma, MAM Pennings, EMF Vandenboorn, ... Angewandte Chemie 135 (37), e202308004, 2023 | 5 | 2023 |
Pharmacological targeting of IRE1 in cancer. Trends Cancer 6, 1018–1030 DP Raymundo, D Doultsinos, X Guillory, A Carlesso, LA Eriksson, ... | 5 | 2020 |
Stereoselective Synthesis of a Bicyclic Norsesquiterpene Backbone–A Possible Route to Nardosinane Derivatives O Selaïmia‐Ferdjani, A Kar, SP Chavan, M Horeau, G Viault, J Pouessel, ... European Journal of Organic Chemistry 2013 (31), 7083-7094, 2013 | 4 | 2013 |
Development of an injectable extracellular matrix for regenerative medicine by silanization of a cellulose derivative in an ionic liquid medium G Xavier, C Nathalie, W Pierre, CJ Sylvia, LB Jean European cells & materials 28 (Supplement 5), 40, 2014 | 2 | 2014 |
Different binding modalities of quercetin to inositol-requiring enzyme 1 of S. cerevisiae and human lead to opposite regulation SJ Mahdizadeh, J Grandén, D Pelizzari-Raymundo, X Guillory, ... Communications Chemistry 7 (1), 6, 2024 | 1 | 2024 |
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient D Leclerc, L Goujon, S Jaillard, B Nouyou, L Cluzeau, L Damaj, ... The CRISPR Journal 6 (1), 17-31, 2023 | 1 | 2023 |
Intramolecular transesterification of depsides yields fluorescent 1H-isochromen-1-ones: Application as a chemical probe for lichen determination S Ferron, P Jéhan, X Guillory, P Uriac Phytochemistry 198, 113139, 2022 | 1 | 2022 |
Gene editing is suitable to treat GM1 Gangliosidosis: a proof-of-concept study D Leclerc, L Goujon, S Jaillard, B Nouyou, L Cluzeau, L Damaj, ... bioRxiv, 2022.04. 17.488473, 2022 | 1 | 2022 |
Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment Q Wu, F Centorrino, X Guillory, M Wolter, C Ottmann, PJ Cossar, ... ChemBioChem 25 (1), e202300636, 2024 | | 2024 |
Linking Chemical Fragments," Gluing" Protein Complexes, Connecting across Cultures EJ Visser, P Jaishankar, E Sijbesma, MAM Pennings, EMF Vandenboorn, ... ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 62 (52), 2023 | | 2023 |
A novel blood brain barrier-permeable IRE1 kinase inhibitor for adjuvant glioblastoma treatment in mice. D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ... | | 2023 |