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Xavier Guillory
Xavier Guillory
Researcher in Medicinal Chemistry & Chemical Biology
Adresse e-mail validée de univ-rennes1.fr - Page d'accueil
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Pharmacological targeting of IRE1 in cancer
DP Raymundo, D Doultsinos, X Guillory, A Carlesso, LA Eriksson, ...
Trends in cancer 6 (12), 1018-1030, 2020
702020
Design polysaccharides of marine origin: chemical modifications to reach advanced versatile compounds
N Chopin, X Guillory, P Weiss, JL Bideau, S Colliec-Jouault
Current Organic Chemistry 18 (7), 867-895, 2014
582014
The molecular tweezer CLR01 stabilizes a disordered protein–protein interface
D Bier, S Mittal, K Bravo-Rodriguez, A Sowislok, X Guillory, J Briels, ...
Journal of the American Chemical Society 139 (45), 16256-16263, 2017
572017
Fragment-based differential targeting of PPI stabilizer interfaces
X Guillory, M Wolter, S Leysen, JF Neves, A Kuusk, S Genet, B Somsen, ...
Journal of medicinal chemistry 63 (13), 6694-6707, 2020
362020
Glycidyl alkoxysilane reactivities towards simple nucleophiles in organic media for improved molecular structure definition in hybrid materials
X Guillory, A Tessier, GO Gratien, P Weiss, S Colliec-Jouault, D Dubreuil, ...
RSC advances 6 (78), 74087-74099, 2016
242016
Structural and molecular bases to IRE1 activity modulation
T Langlais, D Pelizzari-Raymundo, SJ Mahdizadeh, N Gouault, ...
Biochemical Journal 478 (15), 2953-2975, 2021
102021
Mono‐and Bivalent 14‐3‐3 Inhibitors for Characterizing Supramolecular “Lysine Wrapping” of Oligoethylene Glycol (OEG) Moieties in Proteins
E Yilmaz, D Bier, X Guillory, J Briels, YB Ruiz‐Blanco, E Sanchez‐Garcia, ...
Chemistry–A European Journal 24 (52), 13807-13814, 2018
102018
Supramolecular enhancement of a natural 14–3–3 protein ligand
X Guillory, I Hadrovic, PJ de Vink, A Sowislok, L Brunsveld, T Schrader, ...
Journal of the American Chemical Society 143 (34), 13495-13500, 2021
92021
A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment
D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ...
Iscience 26 (5), 2023
62023
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking
EJ Visser, P Jaishankar, E Sijbesma, MAM Pennings, EMF Vandenboorn, ...
Angewandte Chemie 135 (37), e202308004, 2023
52023
Pharmacological targeting of IRE1 in cancer. Trends Cancer 6, 1018–1030
DP Raymundo, D Doultsinos, X Guillory, A Carlesso, LA Eriksson, ...
52020
Stereoselective Synthesis of a Bicyclic Norsesquiterpene Backbone–A Possible Route to Nardosinane Derivatives
O Selaïmia‐Ferdjani, A Kar, SP Chavan, M Horeau, G Viault, J Pouessel, ...
European Journal of Organic Chemistry 2013 (31), 7083-7094, 2013
42013
Development of an injectable extracellular matrix for regenerative medicine by silanization of a cellulose derivative in an ionic liquid medium
G Xavier, C Nathalie, W Pierre, CJ Sylvia, LB Jean
European cells & materials 28 (Supplement 5), 40, 2014
22014
Different binding modalities of quercetin to inositol-requiring enzyme 1 of S. cerevisiae and human lead to opposite regulation
SJ Mahdizadeh, J Grandén, D Pelizzari-Raymundo, X Guillory, ...
Communications Chemistry 7 (1), 6, 2024
12024
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient
D Leclerc, L Goujon, S Jaillard, B Nouyou, L Cluzeau, L Damaj, ...
The CRISPR Journal 6 (1), 17-31, 2023
12023
Intramolecular transesterification of depsides yields fluorescent 1H-isochromen-1-ones: Application as a chemical probe for lichen determination
S Ferron, P Jéhan, X Guillory, P Uriac
Phytochemistry 198, 113139, 2022
12022
Gene editing is suitable to treat GM1 Gangliosidosis: a proof-of-concept study
D Leclerc, L Goujon, S Jaillard, B Nouyou, L Cluzeau, L Damaj, ...
bioRxiv, 2022.04. 17.488473, 2022
12022
Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment
Q Wu, F Centorrino, X Guillory, M Wolter, C Ottmann, PJ Cossar, ...
ChemBioChem 25 (1), e202300636, 2024
2024
Linking Chemical Fragments," Gluing" Protein Complexes, Connecting across Cultures
EJ Visser, P Jaishankar, E Sijbesma, MAM Pennings, EMF Vandenboorn, ...
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 62 (52), 2023
2023
A novel blood brain barrier-permeable IRE1 kinase inhibitor for adjuvant glioblastoma treatment in mice.
D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ...
2023
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