| Ricin: mechanisms of cytotoxicity MJ Lord, NA Jolliffe, CJ Marsden, CSC Pateman, DC Smith, RA Spooner, ... Toxicological reviews 22, 53-64, 2003 | 243 | 2003 |
| Adenovirus with modified binding moiety specific for the target cells RA Spooner, AA Epenetos US Patent 5,885,808, 1999 | 205 | 1999 |
| Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum RA Spooner, PD Watson, CJ Marsden, DC Smith, KAH Moore, JP Cook, ... Biochemical Journal 383 (2), 285-293, 2004 | 181 | 2004 |
| Retrograde transport pathways utilised by viruses and protein toxins RA Spooner, DC Smith, AJ Easton, LM Roberts, MJ Lord Virology Journal 3, 1-10, 2006 | 168 | 2006 |
| Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways E Fuchs, AK Haas, RA Spooner, S Yoshimura, JM Lord, FA Barr The Journal of cell biology 177 (6), 1133-1143, 2007 | 164 | 2007 |
| How ricin and Shiga toxin reach the cytosol of target cells: retrotranslocation from the endoplasmic reticulum RA Spooner, JM Lord Ricin and Shiga Toxins: Pathogenesis, Immunity, Vaccines and Therapeutics, 19-40, 2012 | 163 | 2012 |
| Gene-directed enzyme prodrug therapy with a mustard prodrug/carboxypeptidase G2 combination R Marais, RA Spooner, Y Light, J Martin, CJ Springer Cancer Research 56 (20), 4735-4742, 1996 | 159 | 1996 |
| Gene-directed enzyme prodrug therapy. I Niculescu-Duvaz, R Spooner, R Marais, CJ Springer Bioconjugate chemistry 9 (1), 4-22, 1998 | 154 | 1998 |
| DNA vaccination for cancer treatment. RA Spooner, MP Deonarain, AA Epenetos Gene therapy 2 (3), 173-180, 1995 | 138 | 1995 |
| Genetic delivery of enzymes for cancer therapy. MP Deonarain, RA Spooner, AA Epenetos Gene Therapy 2 (4), 235-244, 1995 | 116 | 1995 |
| Internalized Pseudomonas exotoxin A can exploit multiple pathways to reach the endoplasmic reticulum DC Smith, RA Spooner, PD Watson, JL Murray, TW Hodge, M Amessou, ... Traffic 7 (4), 379-393, 2006 | 107 | 2006 |
| A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy R Marais, RA Spooner, SM Stribbling, Y Light, J Martin, CJ Springer Nature biotechnology 15 (13), 1373-1377, 1997 | 99 | 1997 |
| Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum RA Spooner, PJ Hart, JP Cook, P Pietroni, C Rogon, J Höhfeld, ... Proceedings of the National Academy of Sciences 105 (45), 17408-17413, 2008 | 91 | 2008 |
| Ricin trafficking in plant and mammalian cells JM Lord, RA Spooner Toxins 3 (7), 787-801, 2011 | 89 | 2011 |
| Ricin trafficking in cells RA Spooner, JM Lord Toxins 7 (1), 49-65, 2015 | 88 | 2015 |
| Genetic, Functional and Sequence Analysis of the xylR and xylS Regulatory Genes of the TOL Plasmid pWW0 RA Spooner, K Lindsay, FCH Franklin Microbiology 132 (5), 1347-1358, 1986 | 77 | 1986 |
| Regressions of established breast carcinoma xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect SM Stribbling, F Friedlos, J Martin, L Davies, RA Spooner, R Marais, ... Human gene therapy 11 (2), 285-292, 2000 | 76 | 2000 |
| Retrograde transport of toxins across the endoplasmic reticulum membrane JM Lord, E Deeks, CJ Marsden, K Moore, C Pateman, DC Smith, ... Biochemical Society Transactions 31 (6), 1260-1262, 2003 | 72 | 2003 |
| A recombinant single chain antibody interleukin-2 fusion protein P Savage, A So, RA Spooner, AA Epenetos British journal of cancer 67 (2), 304-310, 1993 | 72 | 1993 |
| Self-immolative nitrogen mustard prodrugs for suicide gene therapy D Niculescu-Duvaz, I Niculescu-Duvaz, F Friedlos, J Martin, R Spooner, ... Journal of medicinal chemistry 41 (26), 5297-5309, 1998 | 71 | 1998 |
Peter WatsonReader, Cardiff UniversityVerified email at cardiff.ac.uk
