Local regulation of gene expression by lncRNA promoters, transcription and splicing JM Engreitz, JE Haines, EM Perez, G Munson, J Chen, M Kane, ... Nature 539 (7629), 452-455, 2016 | 1195 | 2016 |
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome JM Engreitz, A Pandya-Jones, P McDonel, A Shishkin, K Sirokman, ... Science 341 (6147), 1237973, 2013 | 1103 | 2013 |
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 CA McHugh, CK Chen, A Chow, CF Surka, C Tran, P McDonel, ... Nature 521 (7551), 232-236, 2015 | 1099 | 2015 |
Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus SA Quinodoz, N Ollikainen, B Tabak, A Palla, JM Schmidt, E Detmar, ... Cell 174 (3), 744-757. e24, 2018 | 737 | 2018 |
Evaluation of PCR-generated chimeras, mutations, and heteroduplexes with 16S rRNA gene-based cloning X Qiu, L Wu, H Huang, PE McDonel, AV Palumbo, JM Tiedje, J Zhou Applied and environmental microbiology 67 (2), 880-887, 2001 | 521 | 2001 |
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites JM Engreitz, K Sirokman, P McDonel, AA Shishkin, C Surka, P Russell, ... Cell 159 (1), 188-199, 2014 | 501 | 2014 |
Systematic functional dissection of common genetic variation affecting red blood cell traits JC Ulirsch, SK Nandakumar, L Wang, FC Giani, X Zhang, P Rogov, ... Cell 165 (6), 1530-1545, 2016 | 329 | 2016 |
Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing CK Chen, M Blanco, C Jackson, E Aznauryan, N Ollikainen, C Surka, ... Science 354 (6311), 468-472, 2016 | 290 | 2016 |
Ebola virus glycoprotein with increased infectivity dominated the 2013–2016 epidemic WE Diehl, AE Lin, ND Grubaugh, LM Carvalho, K Kim, PP Kyawe, ... Cell 167 (4), 1088-1098. e6, 2016 | 220 | 2016 |
Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development P McDonel, I Costello, B Hendrich The international journal of biochemistry & cell biology 41 (1), 108-116, 2009 | 145 | 2009 |
Recruitment and Spreading of the C. elegans Dosage Compensation Complex Along X Chromosomes G Csankovszki, P McDonel, BJ Meyer Science 303 (5661), 1182-1185, 2004 | 141 | 2004 |
Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex P McDonel, J Jans, BK Peterson, BJ Meyer Nature 444 (7119), 614-618, 2006 | 113 | 2006 |
Sin3a is essential for the genome integrity and viability of pluripotent cells P McDonel, J Demmers, DWM Tan, F Watt, BD Hendrich Developmental biology 363 (1), 62-73, 2012 | 82 | 2012 |
Approaches for understanding the mechanisms of long noncoding RNA regulation of gene expression P McDonel, M Guttman Cold Spring Harbor perspectives in biology 11 (12), a032151, 2019 | 72 | 2019 |
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells Y Wang, L Lifshitz, K Gellatly, CL Vinton, K Busman-Sahay, S McCauley, ... Nature immunology 21 (3), 274-286, 2020 | 69 | 2020 |
Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders A Wakabayashi, JC Ulirsch, LS Ludwig, C Fiorini, M Yasuda, A Choudhuri, ... Proceedings of the National Academy of Sciences 113 (16), 4434-4439, 2016 | 64 | 2016 |
scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in Treg function KJ Gellatly, JP Strassner, K Essien, MA Refat, RL Murphy, ... Science translational medicine 13 (610), eabd8995, 2021 | 59 | 2021 |
Phylogenetic relationships in Gleditsia (Leguminosae) based on ITS sequences A Schnabel, PE McDonel, JF Wendel American Journal of Botany 90 (2), 310-320, 2003 | 48 | 2003 |
Multiple cell and population-level interactions with mouse embryonic stem cell heterogeneity D Cannon, AM Corrigan, A Miermont, P McDonel, JR Chubb Development 142 (16), 2840-2849, 2015 | 28 | 2015 |
High-resolution mapping of multiway enhancer-promoter interactions regulating pathogen detection P Vangala, R Murphy, SA Quinodoz, K Gellatly, P McDonel, M Guttman, ... Molecular cell 80 (2), 359-373. e8, 2020 | 27 | 2020 |