MicroRNA signatures as future biomarkers for diagnosis of diabetes states S Vasu, K Kumano, CM Darden, I Rahman, MC Lawrence, B Naziruddin Cells 8 (12), 1533, 2019 | 144 | 2019 |
Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress S Vasu, RC Moffett, B Thorens, PR Flatt PloS one 9 (6), e101005, 2014 | 89 | 2014 |
Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy RC Moffett, S Vasu, B Thorens, DJ Drucker, PR Flatt PloS one 9 (6), e96863, 2014 | 85 | 2014 |
Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Molecular and cellular endocrinology 436, 102-113, 2016 | 73 | 2016 |
A DPP-IV-resistant triple-acting agonist of GIP, GLP-1 and glucagon receptors with potent glucose-lowering and insulinotropic actions in high-fat-fed mice VK Bhat, BD Kerr, S Vasu, PR Flatt, VA Gault Diabetologia 56, 1417-1424, 2013 | 69 | 2013 |
Cellular responses of novel human pancreatic β-cell line, 1.1 B4 to hyperglycemia S Vasu, NH McClenaghan, JT McCluskey, PR Flatt Islets 5 (4), 170-177, 2013 | 57 | 2013 |
Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1 B4 S Vasu, NH McClenaghan, JT McCluskey, PR Flatt Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (1), 136-145, 2014 | 52 | 2014 |
Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 749-758, 2017 | 47 | 2017 |
Differential expression and release of exosomal miRNAs by human islets under inflammatory and hypoxic stress PB Saravanan, S Vasu, G Yoshimatsu, CM Darden, X Wang, J Gu, ... Diabetologia 62, 1901-1914, 2019 | 45 | 2019 |
Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity S Vasu, RC Moffett, NH McClenaghan, PR Flatt Experimental cell research 336 (1), 100-108, 2015 | 42 | 2015 |
Cellular models for beta‐cell function and diabetes gene therapy AD Green, S Vasu, PR Flatt Acta physiologica 222 (3), e13012, 2018 | 36 | 2018 |
Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice V Pathak, S Vasu, VA Gault, PR Flatt, N Irwin Diabetologia 58, 2144-2153, 2015 | 36 | 2015 |
Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1 B4 S Vasu, NH McClenaghan, JT McCluskey, PR Flatt Biological chemistry 394 (7), 909-918, 2013 | 34 | 2013 |
Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1 B4 cells AD Green, S Vasu, NH McClenaghan, PR Flatt Pflügers Archiv-European Journal of Physiology 467, 2219-2228, 2015 | 28 | 2015 |
Esculentin-2CHa-related peptides modulate islet cell function and improve glucose tolerance in mice with diet-induced obesity and insulin resistance OO Ojo, DK Srinivasan, BO Owolabi, S Vasu, JM Conlon, PR Flatt, ... PLoS One 10 (10), e0141549, 2015 | 27 | 2015 |
Locally produced xenin and the neurotensinergic system in pancreatic islet function and β-cell survival D Khan, S Vasu, RC Moffett, VA Gault, PR Flatt, N Irwin Biological Chemistry 399 (1), 79-92, 2017 | 24 | 2017 |
Expression of gastrin family peptides in pancreatic islets and their role in β-cell function and survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Pancreas 47 (2), 190-199, 2018 | 23 | 2018 |
Differential expression of glucagon-like peptide-2 (GLP-2) is involved in pancreatic islet cell adaptations to stress and beta-cell survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Peptides 95, 68-75, 2017 | 23 | 2017 |
Esculentin-2CHa (1-30) and its analogues: Stability and mechanisms of insulinotropic action S Vasu, MK McGahon, RC Moffett, TM Curtis, JM Conlon, ... J. Endocrinol 232 (3), 423-435, 2017 | 23 | 2017 |
Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice RC Moffett, S Vasu, PR Flatt Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (6), 1206-1214, 2015 | 23 | 2015 |