| α-Synuclein promotes SNARE-complex assembly in vivo and in vitro J Burré, M Sharma, T Tsetsenis, V Buchman, MR Etherton, TC Südhof Science 329 (5999), 1663-1667, 2010 | 2080 | 2010 |
| The synaptic function of α-synuclein J Burré Journal of Parkinson's disease 5 (4), 699-713, 2015 | 582 | 2015 |
| α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation J Burré, M Sharma, TC Südhof Proceedings of the National Academy of Sciences 111 (40), E4274-E4283, 2014 | 525 | 2014 |
| Cell biology and pathophysiology of α-synuclein J Burré, M Sharma, TC Südhof Cold Spring Harbor perspectives in medicine 8 (3), a024091, 2018 | 523 | 2018 |
| Properties of native brain α-synuclein J Burré, S Vivona, J Diao, M Sharma, AT Brunger, TC Südhof Nature 498 (7453), E4-E6, 2013 | 391 | 2013 |
| Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2 J Diao, J Burré, S Vivona, DJ Cipriano, M Sharma, M Kyoung, TC Südhof, ... elife 2, e00592, 2013 | 380 | 2013 |
| CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity M Sharma, J Burré, TC Südhof Nature cell biology 13 (1), 30-39, 2011 | 294 | 2011 |
| Definition of a molecular pathway mediating α-synuclein neurotoxicity J Burré, M Sharma, TC Südhof Journal of Neuroscience 35 (13), 5221-5232, 2015 | 225 | 2015 |
| Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities J Burré, M Sharma, TC Südhof Journal of Neuroscience 32 (43), 15227-15242, 2012 | 209 | 2012 |
| Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis M Morciano, J Burré, C Corvey, M Karas, H Zimmermann, W Volknandt Journal of neurochemistry 95 (6), 1732-1745, 2005 | 180 | 2005 |
| CSPα knockout causes neurodegeneration by impairing SNAP‐25 function M Sharma, J Burré, P Bronk, Y Zhang, W Xu, TC Südhof The EMBO journal 31 (4), 829-841, 2012 | 170 | 2012 |
| Analysis of the synaptic vesicle proteome using three gel‐based protein separation techniques J Burré, T Beckhaus, H Schägger, C Corvey, S Hofmann, M Karas, ... Proteomics 6 (23), 6250-6262, 2006 | 129 | 2006 |
| The synaptic vesicle proteome J Burré, W Volknandt Journal of neurochemistry 101 (6), 1448-1462, 2007 | 122 | 2007 |
| Proteasome inhibition alleviates SNARE-dependent neurodegeneration M Sharma, J Burré, TC Südhof Science translational medicine 4 (147), 147ra113-147ra113, 2012 | 89 | 2012 |
| Synaptotagmin-1 and-7 are redundantly essential for maintaining the capacity of the readily-releasable pool of synaptic vesicles T Bacaj, D Wu, J Burré, RC Malenka, X Liu, TC Südhof PLoS biology 13 (10), e1002267, 2015 | 84 | 2015 |
| STXBP1 encephalopathies: clinical spectrum, disease mechanisms, and therapeutic strategies D Abramov, NGL Guiberson, J Burré Journal of neurochemistry 157 (2), 165-178, 2021 | 72 | 2021 |
| Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones NGL Guiberson, A Pineda, D Abramov, P Kharel, KE Carnazza, RT Wragg, ... Nature communications 9 (1), 3986, 2018 | 70 | 2018 |
| Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca2+ sensitivity C Acuna, Q Guo, J Burré, M Sharma, J Sun, TC Südhof Neuron 82 (5), 1088-1100, 2014 | 69 | 2014 |
| Modulating membrane binding of α-synuclein as a therapeutic strategy A Pineda, J Burré Proceedings of the National Academy of Sciences 114 (6), 1223-1225, 2017 | 63 | 2017 |
| Synaptic vesicle proteins under conditions of rest and activation: Analysis by 2‐D difference gel electrophoresis J Burré, T Beckhaus, C Corvey, M Karas, H Zimmermann, W Volknandt Electrophoresis 27 (17), 3488-3496, 2006 | 52 | 2006 |
Manu SharmaAssistant Professor of Neuroscience, Weill Cornell Medical CollegeVerified email at med.cornell.edu
