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Andrea Casiraghi
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Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ
A Casiraghi, L Suigo, E Valoti, V Straniero
Antibiotics 9 (2), 69, 2020
452020
2, 6‐Difluorobenzamide Inhibitors of Bacterial Cell Division Protein FtsZ: Design, Synthesis, and Structure–Activity Relationships
V Straniero, C Zanotto, L Straniero, A Casiraghi, S Duga, A Radaelli, ...
ChemMedChem 12 (16), 1303-1318, 2017
242017
Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate
G Faustini, F Longhena, A Bruno, F Bono, J Grigoletto, L La Via, A Barbon, ...
Neurobiology of disease 138, 104789, 2020
232020
Benzodioxane‐benzamides as antibacterial agents: computational and SAR studies to evaluate the influence of the 7‐substitution in FtsZ interaction
V Straniero, V Sebastián‐Pérez, M Hrast, C Zanotto, A Casiraghi, L Suigo, ...
ChemMedChem 15 (2), 195-209, 2020
232020
Benzamide derivatives targeting the cell division protein FtsZ: modifications of the linker and the benzodioxane scaffold and their effects on antimicrobial activity
V Straniero, L Suigo, A Casiraghi, V Sebastián-Pérez, M Hrast, C Zanotto, ...
Antibiotics 9 (4), 160, 2020
192020
Computational design and development of benzodioxane-benzamides as potent inhibitors of FtsZ by exploring the hydrophobic subpocket
V Straniero, V Sebastián-Pérez, L Suigo, W Margolin, A Casiraghi, ...
Antibiotics 10 (4), 442, 2021
132021
How do reaction conditions affect the enantiopure synthesis of 2‐substituted‐1, 4‐benzodioxane derivatives?
V Straniero, A Casiraghi, L Fumagalli, E Valoti
Chirality 30 (7), 943-950, 2018
132018
Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux
D Luethi, J Maier, D Rudin, D Szöllősi, TJF Angenoorth, S Stankovic, ...
Communications Biology 5 (1), 1259, 2022
112022
Recent developments in ligands and chemical probes targeting solute carrier transporters
A Casiraghi, A Bensimon, G Superti-Furga
Current Opinion in Chemical Biology 62, 53-63, 2021
112021
Design and Synthesis of Fluorescent Methylphenidate Analogues for a FRET‐Based Assay of Synapsin III Binding
A Casiraghi, F Longhena, V Straniero, G Faustini, AH Newman, A Bellucci, ...
ChemMedChem 15 (14), 1330-1337, 2020
102020
How reaction conditions may influence the regioselectivity in the synthesis of 2, 3-Dihydro-1, 4-benzoxathiine Derivatives
A Casiraghi, E Valoti, L Suigo, A Artasensi, E Sorvillo, V Straniero
The Journal of Organic Chemistry 83 (21), 13217-13227, 2018
102018
Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram
GA Camacho-Hernandez, A Casiraghi, D Rudin, D Luethi, TC Ku, ...
RSC Medicinal Chemistry 12 (7), 1174-1186, 2021
92021
Methylphenidate analogues as a new class of potential disease-modifying agents for Parkinson’s disease: evidence from cell models and alpha-synuclein transgenic mice
A Casiraghi, F Longhena, G Faustini, G Ribaudo, L Suigo, ...
Pharmaceutics 14 (8), 1595, 2022
62022
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation
L Suigo, M Chojnacki, C Zanotto, V Sebastián-Pérez, CDG Morghen, ...
Antibiotics 10 (4), 438, 2021
22021
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
V Dvorak, A Casiraghi, C Colas, A Koren, T Tomek, F Offensperger, ...
Cell Chemical Biology 30 (8), 953-964. e9, 2023
12023
PARKINSON'S DISEASE: VALIDATION OF A NOVEL TARGET THROUGH THE DEVELOPMENT OF METHYLPHENIDATE ANALOGS AS POTENTIAL MODULATOR AND FLUORESCENT PROBES
A Casiraghi
Università degli Studi di Milano, 2020
2020
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