Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ A Casiraghi, L Suigo, E Valoti, V Straniero Antibiotics 9 (2), 69, 2020 | 45 | 2020 |
2, 6‐Difluorobenzamide Inhibitors of Bacterial Cell Division Protein FtsZ: Design, Synthesis, and Structure–Activity Relationships V Straniero, C Zanotto, L Straniero, A Casiraghi, S Duga, A Radaelli, ... ChemMedChem 12 (16), 1303-1318, 2017 | 24 | 2017 |
Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate G Faustini, F Longhena, A Bruno, F Bono, J Grigoletto, L La Via, A Barbon, ... Neurobiology of disease 138, 104789, 2020 | 23 | 2020 |
Benzodioxane‐benzamides as antibacterial agents: computational and SAR studies to evaluate the influence of the 7‐substitution in FtsZ interaction V Straniero, V Sebastián‐Pérez, M Hrast, C Zanotto, A Casiraghi, L Suigo, ... ChemMedChem 15 (2), 195-209, 2020 | 23 | 2020 |
Benzamide derivatives targeting the cell division protein FtsZ: modifications of the linker and the benzodioxane scaffold and their effects on antimicrobial activity V Straniero, L Suigo, A Casiraghi, V Sebastián-Pérez, M Hrast, C Zanotto, ... Antibiotics 9 (4), 160, 2020 | 19 | 2020 |
Computational design and development of benzodioxane-benzamides as potent inhibitors of FtsZ by exploring the hydrophobic subpocket V Straniero, V Sebastián-Pérez, L Suigo, W Margolin, A Casiraghi, ... Antibiotics 10 (4), 442, 2021 | 13 | 2021 |
How do reaction conditions affect the enantiopure synthesis of 2‐substituted‐1, 4‐benzodioxane derivatives? V Straniero, A Casiraghi, L Fumagalli, E Valoti Chirality 30 (7), 943-950, 2018 | 13 | 2018 |
Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux D Luethi, J Maier, D Rudin, D Szöllősi, TJF Angenoorth, S Stankovic, ... Communications Biology 5 (1), 1259, 2022 | 11 | 2022 |
Recent developments in ligands and chemical probes targeting solute carrier transporters A Casiraghi, A Bensimon, G Superti-Furga Current Opinion in Chemical Biology 62, 53-63, 2021 | 11 | 2021 |
Design and Synthesis of Fluorescent Methylphenidate Analogues for a FRET‐Based Assay of Synapsin III Binding A Casiraghi, F Longhena, V Straniero, G Faustini, AH Newman, A Bellucci, ... ChemMedChem 15 (14), 1330-1337, 2020 | 10 | 2020 |
How reaction conditions may influence the regioselectivity in the synthesis of 2, 3-Dihydro-1, 4-benzoxathiine Derivatives A Casiraghi, E Valoti, L Suigo, A Artasensi, E Sorvillo, V Straniero The Journal of Organic Chemistry 83 (21), 13217-13227, 2018 | 10 | 2018 |
Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram GA Camacho-Hernandez, A Casiraghi, D Rudin, D Luethi, TC Ku, ... RSC Medicinal Chemistry 12 (7), 1174-1186, 2021 | 9 | 2021 |
Methylphenidate analogues as a new class of potential disease-modifying agents for Parkinson’s disease: evidence from cell models and alpha-synuclein transgenic mice A Casiraghi, F Longhena, G Faustini, G Ribaudo, L Suigo, ... Pharmaceutics 14 (8), 1595, 2022 | 6 | 2022 |
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation L Suigo, M Chojnacki, C Zanotto, V Sebastián-Pérez, CDG Morghen, ... Antibiotics 10 (4), 438, 2021 | 2 | 2021 |
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors V Dvorak, A Casiraghi, C Colas, A Koren, T Tomek, F Offensperger, ... Cell Chemical Biology 30 (8), 953-964. e9, 2023 | 1 | 2023 |
PARKINSON'S DISEASE: VALIDATION OF A NOVEL TARGET THROUGH THE DEVELOPMENT OF METHYLPHENIDATE ANALOGS AS POTENTIAL MODULATOR AND FLUORESCENT PROBES A Casiraghi Università degli Studi di Milano, 2020 | | 2020 |