| Targeting Wnt signaling in colorectal cancer. A review in the theme: cell signaling: proteins, pathways and mechanisms L Novellasdemunt, P Antas, VSW Li American Journal of Physiology-Cell Physiology 309 (8), C511-C521, 2015 | 353 | 2015 |
| A brief history of organoids C Corrò, L Novellasdemunt, VSW Li American Journal of Physiology-Cell Physiology 319 (1), C151-C165, 2020 | 303 | 2020 |
| Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient … A Méndez-Lucas, P Hyroššová, L Novellasdemunt, F Viñals, JC Perales Journal of Biological Chemistry 289 (32), 22090-22102, 2014 | 198 | 2014 |
| Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy M Tajan, M Hennequart, EC Cheung, F Zani, AK Hock, N Legrave, ... Nature communications 12 (1), 366, 2021 | 165 | 2021 |
| USP7 is a tumor-specific WNT activator for APC-mutated colorectal cancer by mediating β-catenin deubiquitination L Novellasdemunt, V Foglizzo, L Cuadrado, P Antas, A Kucharska, ... Cell reports 21 (3), 612-627, 2017 | 137 | 2017 |
| Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure L Meran, I Massie, S Campinoti, AE Weston, R Gaifulina, L Tullie, P Faull, ... Nature medicine 26 (10), 1593-1601, 2020 | 108 | 2020 |
| Identifying strategies to target the metabolic flexibility of tumours A Méndez-Lucas, W Lin, PC Driscoll, N Legrave, L Novellasdemunt, C Xie, ... Nature metabolism 2 (4), 335-350, 2020 | 99 | 2020 |
| Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene A Ruiz-García, E Monsalve, L Novellasdemunt, A Navarro-Sabaté, ... Journal of Biological Chemistry 286 (22), 19247-19258, 2011 | 94 | 2011 |
| Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFKFB2) isoenzyme by amino acids L Novellasdemunt, I Tato, A Navarro-Sabate, M Ruiz-Meana, ... Journal of Biological Chemistry 288 (15), 10640-10651, 2013 | 91 | 2013 |
| PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli L Novellasdemunt, L Bultot, A Manzano, F Ventura, JL Rosa, ... Biochemical Journal 452 (3), 531-543, 2013 | 83 | 2013 |
| Progestins activate 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 (PFKFB3) in breast cancer cells L Novellasdemunt, M Obach, L Millán-Ariño, A Manzano, F Ventura, ... Biochemical Journal 442 (2), 345-356, 2012 | 66 | 2012 |
| Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells A Cañellas-Socias, C Cortina, X Hernando-Momblona, S Palomo-Ponce, ... Nature 611 (7936), 603-613, 2022 | 65 | 2022 |
| NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor L Novellasdemunt, A Kucharska, C Jamieson, M Prange‐Barczynska, ... The EMBO journal 39 (3), e102771, 2020 | 65 | 2020 |
| Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes A Houddane, L Bultot, L Novellasdemunt, M Johanns, MA Gueuning, ... Cellular signalling 34, 23-37, 2017 | 63 | 2017 |
| Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy A Alvarez-Varela, L Novellasdemunt, FM Barriga, X Hernando-Momblona, ... Nature Cancer 3 (9), 1052-1070, 2022 | 48 | 2022 |
| The transcription co-repressors MTG8 and MTG16 regulate exit of intestinal stem cells from their niche and differentiation into enterocyte vs secretory lineages A Baulies, N Angelis, V Foglizzo, ET Danielsen, H Patel, ... Gastroenterology 159 (4), 1328-1341. e3, 2020 | 30 | 2020 |
| SH3BP4 regulates intestinal stem cells and tumorigenesis by modulating β-Catenin nuclear localization P Antas, L Novellasdemunt, A Kucharska, I Massie, J Carvalho, D Oukrif, ... Cell reports 26 (9), 2266-2273. e4, 2019 | 23 | 2019 |
| Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway A Sánchez-Botet, E Quandt, N Masip, R Escribá, L Novellasdemunt, ... Cellular Oncology 44, 1273-1286, 2021 | 8 | 2021 |
| USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development L Novellasdemunt, A Kucharska, A Baulies, C Hutton, G Vlachogiannis, ... Stem Cell Reports 18 (2), 570-584, 2023 | 7 | 2023 |
| PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3) L Novellasdemunt, À Navarro i Sabaté, A Manzano Cuesta, ... Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013, vol …, 2013 | 6 | 2013 |
