TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging P Davizon-Castillo, B McMahon, S Aguila, D Bark, K Ashworth, A Allawzi, ... Blood, The Journal of the American Society of Hematology 134 (9), 727-740, 2019 | 221 | 2019 |
The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi M Ghasemzadeh, ZS Kaplan, I Alwis, SM Schoenwaelder, KJ Ashworth, ... Blood, The Journal of the American Society of Hematology 121 (22), 4555-4566, 2013 | 154 | 2013 |
High shear–dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction SL Cranmer, KJ Ashworth, Y Yao, MC Berndt, ZM Ruggeri, RK Andrews, ... Blood, The Journal of the American Society of Hematology 117 (9), 2718-2727, 2011 | 101 | 2011 |
Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia Y Yuan, I Alwis, MCL Wu, Z Kaplan, K Ashworth, D Bark Jr, A Pham, ... Science Translational Medicine 9 (409), eaam5861, 2017 | 67 | 2017 |
Turbulent flow promotes cleavage of VWF (von Willebrand factor) by ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type-1 motif, member 13) M Bortot, K Ashworth, A Sharifi, F Walker, NC Crawford, KB Neeves, ... Arteriosclerosis, thrombosis, and vascular biology 39 (9), 1831-1842, 2019 | 44 | 2019 |
Platelet α-granules are required for occlusive high-shear-rate thrombosis DA Kim, KJ Ashworth, J Di Paola, DN Ku Blood advances 4 (14), 3258-3267, 2020 | 17 | 2020 |
Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels M Lehmann, K Ashworth, M Manco‐Johnson, J Di Paola, KB Neeves, ... Journal of Thrombosis and Haemostasis 16 (1), 104-115, 2018 | 17 | 2018 |
Pathologic shear and elongation rates do not cause cleavage of von Willebrand factor by ADAMTS13 in a purified system M Bortot, A Sharifi, K Ashworth, F Walker, A Cox, K Ruegg, N Clendenen, ... Cellular and Molecular Bioengineering 13, 379-390, 2020 | 12 | 2020 |
Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels CJ Ng, A Liu, S Venkataraman, KJ Ashworth, CD Baker, R O’Rourke, ... Blood, The Journal of the American Society of Hematology 139 (14), 2240-2251, 2022 | 10 | 2022 |
Effects of anti‐β2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity CJ Ng, KR McCrae, K Ashworth, LJ Sosa, V Betapudi, ... Research and Practice in Thrombosis and Haemostasis 2 (2), 380-389, 2018 | 10 | 2018 |
SVEP1 is an endogenous ligand for the orphan receptor PEAR1 JS Elenbaas, U Pudupakkam, KJ Ashworth, CJ Kang, V Patel, K Santana, ... Nature communications 14 (1), 850, 2023 | 8 | 2023 |
Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors C Zhou, R Uluisik, JW Rowley, C David, CL Jones, CD Scharer, L Noetzli, ... Experimental hematology 112, 24-34, 2022 | 7 | 2022 |
Negatively charged nanoparticles of multiple materials inhibit shear-induced platelet accumulation MT Griffin, K Ashworth, N Hill, J von Behren, J Di Paola, DN Ku Nanomedicine: Nanotechnology, Biology and Medicine 35, 102405, 2021 | 4 | 2021 |
Flow devices to assess platelet function: historical evolution and current choices RCLS Silva, EF Grabowski Seminars in Thrombosis and Hemostasis 45 (03), 297-301, 2019 | 4 | 2019 |
A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia SB Koukouritaki, AMM Thinn, KJ Ashworth, J Fang, HS Slater, LM Du, ... Blood Advances 7 (13), 3180-3191, 2023 | 3 | 2023 |
Epigenetic Profiles of Primary Endothelial Cells from Patients with Low VWF Levels CJ Ng, A Liu, KJ Ashworth, KL Jones, J Di Paola Blood 132, 983, 2018 | 3 | 2018 |
Pro-inflammatory cytokines drive the development of a prothrombotic platelet phenotype in inflammation and aging P Davizon-Castillo, K Ashworth, K Higa, G Hernandez, S Acharya, ... Blood 128 (22), 3747, 2016 | 3 | 2016 |
Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms F He, ABA Laranjeira, T Kong, S Lin, KJ Ashworth, A Liu, NM Lasky, ... The Journal of Clinical Investigation 134 (3), 2024 | 2 | 2024 |
Von Willebrand Factor and Platelet Aggregation: from Bench to Clinical Practice KJ Ashworth, KA Thomas, SM Shea Current Anesthesiology Reports 12 (2), 329-341, 2022 | 1 | 2022 |
Differentiation of patients with symptomatic low von Willebrand factor from those with asymptomatic low von Willebrand factor EF Grabowski, EM Van Cott, L Bornikova, DC Boyle, RL Silva Thrombosis and Haemostasis 120 (05), 793-804, 2020 | 1 | 2020 |