MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ... Nature communications 12 (1), 470, 2021 | 113 | 2021 |
A synthetic lethal drug combination mimics glucose deprivation–induced cancer cell death in the presence of glucose JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham Journal of Biological Chemistry 295 (5), 1350-1365, 2020 | 65 | 2020 |
Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin A Flores, S Sandoval-Gonzalez, R Takahashi, A Krall, L Sathe, L Wei, ... Nature communications 10 (1), 91, 2019 | 43 | 2019 |
Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets JH Joly, WE Lowry, NA Graham Bioinformatics 36 (21), 5247-5254, 2020 | 25 | 2020 |
The landscape of metabolic pathway dependencies in cancer cell lines JH Joly, BTL Chew, NA Graham PLoS Computational Biology 17 (4), e1008942, 2021 | 13 | 2021 |
Glutamine-dependent signaling controls pluripotent stem cell fate V Lu, IJ Roy, A Torres, JH Joly, FM Ahsan, NA Graham, MA Teitell Developmental cell 57 (5), 610-623. e8, 2022 | 9 | 2022 |
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun 12: 470 JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ... S41467-020-20790-0. Crossref| PubMed| ISI, 2021 | 4 | 2021 |
NADPH consumption by L-cystine reduction creates a metabolic vulnerability upon glucose deprivation JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham bioRxiv, 733162, 2019 | 2 | 2019 |
Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing BB Garana, JH Joly, A Delfarah, H Hong, NA Graham BMC bioinformatics 24 (1), 215, 2023 | | 2023 |
Drugsea: A Bioinformatic Tool to Identify Classes of Drugs with Differential Sensitivity B Garana, J Joly, PJ Jeon, N Graham 2021 AIChE Annual Meeting, 2021 | | 2021 |
Discovery of senescence biomarkers and senolytic drugs by proteomic profiling A Delfarah, DQ Zheng, JH Joly, J Yang, NA Graham bioRxiv, 2020.09. 22.309351, 2020 | | 2020 |
Mitochondrial-Encoded Peptide MOTS-c is an Exercise-Induced Regulator of Aging Metabolic Homeostasis and Physical Capacity JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ... bioRxiv, 2019.12. 22.886432, 2019 | | 2019 |
Development of Synthetic Lethal Drug Combinations Targeting Metabolic Vulnerabilities in Glioblastoma Cells J Joly, B Garana, P Phung, S Parrish, N Graham 2019 AIChE Annual Meeting, 2019 | | 2019 |