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James Joly
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MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ...
Nature communications 12 (1), 470, 2021
1132021
A synthetic lethal drug combination mimics glucose deprivation–induced cancer cell death in the presence of glucose
JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham
Journal of Biological Chemistry 295 (5), 1350-1365, 2020
652020
Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin
A Flores, S Sandoval-Gonzalez, R Takahashi, A Krall, L Sathe, L Wei, ...
Nature communications 10 (1), 91, 2019
432019
Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets
JH Joly, WE Lowry, NA Graham
Bioinformatics 36 (21), 5247-5254, 2020
252020
The landscape of metabolic pathway dependencies in cancer cell lines
JH Joly, BTL Chew, NA Graham
PLoS Computational Biology 17 (4), e1008942, 2021
132021
Glutamine-dependent signaling controls pluripotent stem cell fate
V Lu, IJ Roy, A Torres, JH Joly, FM Ahsan, NA Graham, MA Teitell
Developmental cell 57 (5), 610-623. e8, 2022
92022
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun 12: 470
JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ...
S41467-020-20790-0. Crossref| PubMed| ISI, 2021
42021
NADPH consumption by L-cystine reduction creates a metabolic vulnerability upon glucose deprivation
JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham
bioRxiv, 733162, 2019
22019
Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing
BB Garana, JH Joly, A Delfarah, H Hong, NA Graham
BMC bioinformatics 24 (1), 215, 2023
2023
Drugsea: A Bioinformatic Tool to Identify Classes of Drugs with Differential Sensitivity
B Garana, J Joly, PJ Jeon, N Graham
2021 AIChE Annual Meeting, 2021
2021
Discovery of senescence biomarkers and senolytic drugs by proteomic profiling
A Delfarah, DQ Zheng, JH Joly, J Yang, NA Graham
bioRxiv, 2020.09. 22.309351, 2020
2020
Mitochondrial-Encoded Peptide MOTS-c is an Exercise-Induced Regulator of Aging Metabolic Homeostasis and Physical Capacity
JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ...
bioRxiv, 2019.12. 22.886432, 2019
2019
Development of Synthetic Lethal Drug Combinations Targeting Metabolic Vulnerabilities in Glioblastoma Cells
J Joly, B Garana, P Phung, S Parrish, N Graham
2019 AIChE Annual Meeting, 2019
2019
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Articles 1–13