| Structural insights into differences in G protein activation by family A and family B GPCRs D Hilger, KK Kumar, H Hu, MF Pedersen, ES O’Brien, L Giehm, ... Science 369 (6503), eaba3373, 2020 | 118 | 2020 |
| Defining the Apoptotic Trigger: The Interaction of Cytochrome c and Cardiolipin ES O'Brien, NV Nucci, B Fuglestad, C Tommos, AJ Wand Journal of Biological Chemistry 290 (52), 30879-30887, 2015 | 70 | 2015 |
| On the relationship between NMR‐derived amide order parameters and protein backbone entropy changes KA Sharp, E O'Brien, V Kasinath, AJ Wand Proteins: Structure, Function, and Bioinformatics 83 (5), 922-930, 2015 | 68 | 2015 |
| Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids I Dodevski, NV Nucci, KG Valentine, GK Sidhu, ES O’Brien, A Pardi, ... Journal of the American Chemical Society 136 (9), 3465-3474, 2014 | 60 | 2014 |
| Membrane proteins have distinct fast internal motion and residual conformational entropy ES O'Brien, B Fuglestad, HJ Lessen, MA Stetz, DW Lin, BS Marques, ... Angewandte Chemie International Edition 59 (27), 11108-11114, 2020 | 30 | 2020 |
| Improving yields of deuterated, methyl labeled protein by growing in H2O ES O’Brien, DW Lin, B Fuglestad, MA Stetz, T Gosse, C Tommos, ... Journal of biomolecular NMR 71, 263-273, 2018 | 23 | 2018 |
| On the ability of molecular dynamics force fields to recapitulate NMR derived protein side chain order parameters ES O'Brien, AJ Wand, KA Sharp Protein Science 25 (6), 1156-1160, 2016 | 20 | 2016 |
| Negative allosteric modulation of the glucagon receptor by RAMP2 K Krishna Kumar, ES O'Brien, CH Habrian, NR Latorraca, H Wang, ... Cell 186 (7), 1465-1477, 2023 | 15 | 2023 |
| The unusual internal motion of the villin headpiece subdomain KW Harpole, ES O'Brien, MA Clark, CJ McKnight, L Vugmeyster, AJ Wand Protein Science 25 (2), 423-432, 2016 | 7 | 2016 |
| Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy J Zhao, M Elgeti, ES O’Brien, CP Sár, AEI Daibani, J Heng, X Sun, T Che, ... BioRxiv, 2023 | 4 | 2023 |
| Step-wise activation of a Family C GPCR KK Kumar, H Wang, C Habrian, NR Latorraca, J Xu, ES O’Brien, C Zhang, ... bioRxiv, 2023 | 2 | 2023 |
| Negative allosteric modulation of the glucagon receptor by RAMP2 ES O'Brien, KK Kumar, C Habrian, NR Latorraca, H Wang, I Tuneew, ... Biophysical Journal 122 (3), 161a, 2023 | 1 | 2023 |
| Stepwise activation of a metabotropic glutamate receptor K Krishna Kumar, H Wang, C Habrian, NR Latorraca, J Xu, ES O’Brien, ... Nature, 1-6, 2024 | | 2024 |
| Ligand efficacy modulates conformational dynamics of the µ-opioid receptor J Zhao, M Elgeti, ES O’Brien, CP Sár, A EI Daibani, J Heng, X Sun, ... Nature, 1-7, 2024 | | 2024 |
| Negative allosteric modulation of the µ-opioid receptor ES O'Brien, VA Rangari, A El Daibani, SO Eans, B White, H Wang, ... Biophysical Journal 123 (3), 353a, 2024 | | 2024 |
| Large library docking for cannabinoid-1 receptor agonists with reduced side effects TA Tummino, C Iliopoulos-Tsoutsouvas, JM Braz, ES O'Brien, RM Stein, ... bioRxiv, 2024 | | 2024 |
| Structure, Function & Dynamics at the Membrane ES O’Brien University of Pennsylvania, 2018 | | 2018 |
| Confined Space, Structural Biology, Biophysics and Drug Discovery B Fuglestad, C Jorge, B Marques, NV Nucci, E O’Brien, KG Valentine, ... Biophysical Journal 108 (2), 616a-617a, 2015 | | 2015 |
| The Beginning of the End: Cardiolipin, Cytochrome C and the Apoptotic Trigger ES O’Brien, NV Nucci, B Fuglestad, KG Valentine, AJ Wand Biophysical Journal 108 (2), 90a-91a, 2015 | | 2015 |
| Stepwise activation of a metabotropic glutamate receptor KK Kumar, H Wang, C Habrian, NR Latorraca, J Xu, ES O'Brien, C Zhang, ... Nature, 0 | | |
