Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells L Skalniak, KM Zak, K Guzik, K Magiera, B Musielak, M Pachota, ... Oncotarget 8 (42), 72167, 2017 | 256 | 2017 |
Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses V Napolitano, A Dabrowska, K Schorpp, A Mourão, E Barreto-Duran, ... Cell Chemical Biology 29 (5), 774-784. e8, 2022 | 37 | 2022 |
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity A Czarna, J Plewka, L Kresik, A Matsuda, A Karim, C Robinson, ... Structure 30 (8), 1050-1054. e2, 2022 | 23 | 2022 |
Inhibition of herpes simplex viruses by cationic dextran derivatives M Pachota, K Klysik, A Synowiec, J Ciejka, K Szczubiałka, K Pyrć, ... Journal of Medicinal Chemistry 60 (20), 8620-8630, 2017 | 18 | 2017 |
Cat flu: Broad spectrum polymeric antivirals A Synowiec, I Gryniuk, M Pachota, Ł Strzelec, O Roman, ... Antiviral Research 170, 104563, 2019 | 16 | 2019 |
Highly effective and safe polymeric inhibitors of herpes simplex virus in vitro and in vivo M Pachota, K Kłysik-Trzciańska, A Synowiec, S Yukioka, SI Yusa, ... ACS applied materials & interfaces 11 (30), 26745-26752, 2019 | 10 | 2019 |
Novel peptidyl α-aminoalkylphosphonates as inhibitors of hepatitis C virus NS3/4A protease M Skoreński, M Pachota, K Pyrć, M Sieńczyk, J Oleksyszyn Antiviral Research 144, 286-298, 2017 | 9 | 2017 |
Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget 8 (42): 72167–72181 L Skalniak, KM Zak, K Guzik, K Magiera, B Musielak, M Pachota, ... | 6 | 2017 |
Despite the odds: formation of the SARS-CoV-2 methylation complex A Matsuda, J Plewka, M Rawski, A Mourão, W Zajko, T Siebenmorgen, ... Nucleic Acids Research, gkae165, 2024 | 4 | 2024 |
Novel inhibitors of HSV-1 protease effective in vitro and in vivo M Pachota, R Grzywa, J Iwanejko, A Synowiec, D Iwan, K Kamińska, ... Antiviral Research 213, 105604, 2023 | 4 | 2023 |
Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget 8, 72167–72181 L Skalniak, KM Zak, K Guzik, K Magiera, B Musielak, M Pachota, ... | 4 | 2017 |
Feline herpesvirus 1 (FHV-1) enters the cell by receptor-mediated endocytosis A Synowiec, A Dąbrowska, M Pachota, M Baouche, K Owczarek, ... Journal of Virology 97 (8), e00681-23, 2023 | 2 | 2023 |
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.(preprint) A Czarna, J Plewka, L Kresik, A Matsuda, A Karim, C Robinson, SO Byrne, ... | 1 | 2022 |
Sulfonated polystyrene derivative for use in the treatment and/or prophylaxis of cat flu A Synowiec, M Pachota, K Pyrc, M Nowakowska, K Szczubialka US Patent 11,857,566, 2024 | | 2024 |
Fixed-target time-resolved crystallography at XFELs: the scourge of light contamination but reduced sample consumption G Gotthard, A Flores-Ibarra, M Carrillo, MW Kepa, TJ Mason, ... bioRxiv, 2023.12. 12.571218, 2023 | | 2023 |
Despite the odds: formation of the SARS-CoV-2 methylation complex.(preprint) A Matsuda, J Plewka, Y Chykunova, AN Jones, M Pachota, M Rawski, ... | | 2022 |
Acriflavine, a clinically aproved drug, inhibits SARS-CoV-2 and other betacoronaviruses (preprint) V Napolitano, A Dabrowska, K Schorpp, A Mourao, E Barreto-Duran, ... | | 2021 |
Application of cationic derivative of dextrane for retardation of HSV-1 viral replication M Nowakowska, P Krzysztof, K Pyrć, K SZCZUBIAŁKA, K Szczubiałka, ... | | 2020 |
Biological role of MCPIP2 during viral infection of central nervous system A Solecka, M Wawro, W Sowinska, A Milewska, M Pachota, K Pyrc, ... FEBS OPEN BIO 9, 69-69, 2019 | | 2019 |
HSV-1 protease-the expression and activity R Grzywa, M Wysocka, M Pachota, C Mackereth, A Lesner, K Pyrć, ... Laboratory of Medical Chemistry, 2019 | | 2019 |