| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10690 | 2021 |
| Fusion protein linkers: property, design and functionality X Chen, JL Zaro, WC Shen Advanced drug delivery reviews 65 (10), 1357-1369, 2013 | 1952 | 2013 |
| Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives LN Patel, JL Zaro, WC Shen Pharmaceutical research 24, 1977-1992, 2007 | 539 | 2007 |
| cis-Aconityl spacer between daunomycin and macromolecular carriers: a model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate WC Shen, HJP Ryser Biochemical and Biophysical Research Communications 102 (3), 1048-1054, 1981 | 404 | 1981 |
| Conjugation of methotrexate to poly (L-lysine) increases drug transport and overcomes drug resistance in cultured cells HJP Ryser, WC Shen Proceedings of the National Academy of Sciences 75 (8), 3867-3870, 1978 | 343 | 1978 |
| Conjugation of poly-L-lysine to albumin and horseradish peroxidase: a novel method of enhancing the cellular uptake of proteins. WC Shen, HJ Ryser Proceedings of the National Academy of Sciences 75 (4), 1872-1876, 1978 | 314 | 1978 |
| Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. EP Feener, WC Shen, HJ Ryser Journal of Biological Chemistry 265 (31), 18780-18785, 1990 | 274 | 1990 |
| Mechanisms of TfR-mediated transcytosis and sorting in epithelial cells and applications toward drug delivery A Widera, F Norouziyan, WC Shen Advanced drug delivery reviews 55 (11), 1439-1466, 2003 | 213 | 2003 |
| Insertion of the designed helical linker led to increased expression of tf-based fusion proteins N Amet, HF Lee, WC Shen Pharmaceutical research 26, 523-528, 2009 | 175 | 2009 |
| Recombinant granulocyte colony-stimulating factor-transferrin fusion protein as an oral myelopoietic agent Y Bai, DK Ann, WC Shen Proceedings of the National Academy of Sciences 102 (20), 7292-7296, 2005 | 171 | 2005 |
| Poly (L-lysine) and poly (D-lysine) conjugates of methotrexate: different inhibitory effect on drug resistant cells WC Shen, HJP RYSER Molecular Pharmacology 16 (2), 614-622, 1979 | 155 | 1979 |
| Reversible lipidization for the oral delivery of salmon calcitonin J Wang, D Chow, H Heiati, WC Shen Journal of controlled release 88 (3), 369-380, 2003 | 149 | 2003 |
| Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats CQ Xia, J Wang, WC Shen Journal of Pharmacology and Experimental Therapeutics 295 (2), 594-600, 2000 | 146 | 2000 |
| Improving the oral efficacy of recombinant granulocyte colony-stimulating factor and transferrin fusion protein by spacer optimization Y Bai, WC Shen Pharmaceutical research 23, 2116-2121, 2006 | 138 | 2006 |
| Transcellular delivery of an insulin‐transferrin conjugate in enterocyte‐like Caco‐2 cells D Shah, W Shen Journal of pharmaceutical sciences 85 (12), 1306-1311, 1996 | 135 | 1996 |
| Compositions and methods for enhanced transepithelial and transendothelial transport or active agents WC Shen, J Wan US Patent 5,254,342, 1993 | 135 | 1993 |
| Quantitative comparison of membrane transduction and endocytosis of oligopeptides JL Zaro, WC Shen Biochemical and biophysical research communications 307 (2), 241-247, 2003 | 124 | 2003 |
| Method of effecting cellular uptake of molecules HJP Ryser, WC Shen US Patent 4,847,240, 1989 | 121 | 1989 |
| Human growth hormone–transferrin fusion protein for oral delivery in hypophysectomized rats N Amet, W Wang, WC Shen Journal of controlled release 141 (2), 177-182, 2010 | 118 | 2010 |
| Disulfide spacer between methotrexate and poly(D-lysine): A probe for exploring the reductive process in endocytosis WC Shen, HJP Ryser, LM Laura Journal of Biological Chemistry 260, 10905-10908, 1985 | 118 | 1985 |
