| Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 RS Thwaites, A Sanchez Sevilla Uruchurtu, MK Siggins, F Liew, ... Science immunology 6 (57), eabg9873, 2021 | 175 | 2021 |
| Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase NN Lynskey, M Reglinski, D Calay, MK Siggins, JC Mason, M Botto, ... PLoS pathogens 13 (8), e1006493, 2017 | 66 | 2017 |
| PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury E Triantafyllou, CLC Gudd, MA Mawhin, HC Husbyn, FM Trovato, ... The Journal of clinical investigation 131 (4), 2021 | 65 | 2021 |
| Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody MK Siggins, AF Cunningham, JL Marshall, JL Chamberlain, ... The Journal of immunology 186 (4), 2365-2371, 2011 | 60 | 2011 |
| SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination F Liew, S Talwar, A Cross, BJ Willett, S Scott, N Logan, MK Siggins, ... EBioMedicine 87, 2023 | 58 | 2023 |
| Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen PJ Hart, CM O’Shaughnessy, MK Siggins, S Bobat, RA Kingsley, ... PloS one 11 (1), e0145945, 2016 | 57 | 2016 |
| Durability of immunity to SARS-CoV-2 and other respiratory viruses MK Siggins, RS Thwaites, PJM Openshaw Trends in Microbiology 29 (7), 648-662, 2021 | 54 | 2021 |
| Frequency of transmission, asymptomatic shedding, and airborne spread of Streptococcus pyogenes in schoolchildren exposed to scarlet fever: a prospective, longitudinal … R Cordery, AK Purba, L Begum, E Mills, M Mosavie, A Vieira, ... The Lancet Microbe 3 (5), e366-e375, 2022 | 41 | 2022 |
| Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection MK Siggins, NN Lynskey, LE Lamb, LA Johnson, KK Huse, M Pearson, ... Nature Communications 11 (1), 4697, 2020 | 33 | 2020 |
| Differential timing of antibody‐mediated phagocytosis and cell‐free killing of invasive African Salmonella allows immune evasion MK Siggins, CM O'shaughnessy, J Pravin, AF Cunningham, ... European journal of immunology 44 (4), 1093-1098, 2014 | 25 | 2014 |
| PHiD-CV induces anti-Protein D antibodies but does not augment pulmonary clearance of nontypeable Haemophilus influenzae in mice MK Siggins, SK Gill, PR Langford, Y Li, SN Ladhani, JS Tregoning Vaccine 33 (38), 4954-4961, 2015 | 23 | 2015 |
| Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19 MK Siggins, K Davies, R Fellows, RS Thwaites, JK Baillie, MG Semple, ... Immunology 168 (3), 473-492, 2023 | 18 | 2023 |
| Procalcitonin is not a reliable biomarker of bacterial coinfection in people with coronavirus disease 2019 undergoing microbiological investigation at the time of hospital … KA Relph, CD Russell, CJ Fairfield, L Turtle, TI De Silva, MK Siggins, ... Open forum infectious diseases 9 (5), ofac179, 2022 | 13 | 2022 |
| Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species JF Gibson, GR Pidwill, OT Carnell, BGJ Surewaard, D Shamarina, ... PLoS Pathogens 17 (9), e1009880, 2021 | 12 | 2021 |
| Toxic shock syndrome toxin 1 evaluation and antibiotic impact in a transgenic model of staphylococcal soft tissue infection H Sharma, CE Turner, MK Siggins, M El-Bahrawy, B Pichon, A Kearns, ... Msphere 4 (5), 10.1128/msphere. 00665-19, 2019 | 12 | 2019 |
| Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus DS Smith, MK Siggins, M Gierula, B Pichon, CE Turner, NN Lynskey, ... Microbial genomics 2 (2), e000049, 2016 | 12 | 2016 |
| Bacterial lymphatic metastasis in infection and immunity MK Siggins, S Sriskandan Cells 11 (1), 33, 2021 | 11 | 2021 |
| Elevated antiviral, myeloid and endothelial inflammatory markers in severe COVID-19 RS Thwaites, AS Sevilla Uruchurtu, M Siggins, F Liew, CD Russell, ... MedRxiv, 2020.10. 08.20209411, 2020 | 7 | 2020 |
| Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread LE Lamb, MK Siggins, C Scudamore, W Macdonald, CE Turner, ... Virulence 9 (1), 1074-1084, 2018 | 5 | 2018 |
| An adsorption method to prepare specific antibody-depleted normal human serum as a source of complement for human serum bactericidal assays for Salmonella MK Siggins, CA MacLennan Vaccine 39 (51), 7503-7509, 2021 | 3 | 2021 |
Shiranee SriskandanImperial College LondonVerified email at imperial.ac.uk
