Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling T Oka, J Xu, RA Kaiser, J Melendez, M Hambleton, MA Sargent, A Lorts, ... Circulation research 101 (3), 313-321, 2007 | 542 | 2007 |
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes I Shiraishi, J Melendez, Y Ahn, M Skavdahl, E Murphy, S Welch, ... Circulation research 94 (7), 884-891, 2004 | 249 | 2004 |
Signaling role of Cdc42 in regulating mammalian physiology J Melendez, M Grogg, Y Zheng Journal of Biological Chemistry 286 (4), 2375-2381, 2011 | 183 | 2011 |
Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis AS Galvez, A Diwan, AM Odley, HS Hahn, H Osinska, JG Melendez, ... Circulation research 100 (7), 1071-1078, 2007 | 143 | 2007 |
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation K Katayama, J Melendez, JM Baumann, JR Leslie, BK Chauhan, ... Proceedings of the National Academy of Sciences 108 (18), 7607-7612, 2011 | 127 | 2011 |
Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice J Melendez, M Liu, L Sampson, S Akunuru, X Han, J Vallance, D Witte, ... Gastroenterology 145 (4), 808-819, 2013 | 115 | 2013 |
High rates of survival and fertilization of mouse and hamster oocytes after vitrification in dimethylsulphoxide MJ Wood, C Barros, CJ Candy, J Carroll, J Melendez, DG Whittingham Biology of reproduction 49 (3), 489-495, 1993 | 92 | 1993 |
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts J Melendez, K Stengel, X Zhou, BK Chauhan, M Debidda, P Andreassen, ... Journal of biological chemistry 286 (17), 15132-15137, 2011 | 89 | 2011 |
Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin J Melendez, C Turner, H Avraham, SF Steinberg, E Schaefer, ... Journal of Biological Chemistry 279 (51), 53516-53523, 2004 | 83 | 2004 |
Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly L Chen, J Melendez, K Campbell, CY Kuan, Y Zheng Developmental biology 325 (1), 162-170, 2009 | 82 | 2009 |
Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling J Melendez, S Welch, E Schaefer, CS Moravec, S Avraham, H Avraham, ... Journal of Biological Chemistry 277 (47), 45203-45210, 2002 | 59 | 2002 |
Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes R Foncea, A Gálvez, V Pérez, MP Morales, A Calixto, J Meléndez, ... Biochemical and biophysical research communications 273 (2), 736-744, 2000 | 50 | 2000 |
Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy R Ebensperger, E Acevedo, J Meléndez, R Corbalán, M Acevedo, ... Biochemical and biophysical research communications 243 (1), 20-24, 1998 | 44 | 1998 |
RHOA GTPase controls YAP-mediated EREG signaling in small intestinal stem cell maintenance M Liu, Z Zhang, L Sampson, X Zhou, K Nalapareddy, Y Feng, S Akunuru, ... Stem cell reports 9 (6), 1961-1975, 2017 | 38 | 2017 |
Immunolocalization of proacrosin/acrosin in rabbit sperm during acrosome reaction and in spermatozoa recovered from the perivitelline space M Valdivia, R Yunes, J Melendez, AE De Ioannes, L Leyton, MI Becker, ... Molecular reproduction and development 37 (2), 216-222, 1994 | 29 | 1994 |
Cyclic AMP-dependent protein kinase and mechanical heart function in ventricular hypertrophy induced by pressure overload or secondary to myocardial infarction AM Piddo, MI Sánchez, M Sapag-Hagar, R Corbalán, R Foncea, ... Journal of molecular and cellular cardiology 28 (5), 1073-1083, 1996 | 27 | 1996 |
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo AM Zárate, C Espinosa-Bustos, S Guerrero, A Fierro, F Oyarzún-Ampuero, ... International journal of molecular sciences 22 (16), 8372, 2021 | 14 | 2021 |
New imidoyl-indazole platinum (II) complexes as potential anticancer agents: Synthesis, evaluation of cytotoxicity, cell death and experimental-theoretical DNA interaction studies AR Cabrera, C Espinosa-Bustos, M Faúndez, J Meléndez, P Jaque, ... Journal of Inorganic Biochemistry 174, 90-101, 2017 | 13 | 2017 |
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat JE Jalil, R Ebensperger, J Meléndez, E Acevedo, M Sapag-Hagar, ... Life sciences 64 (18), 1603-1612, 1999 | 12 | 1999 |
Sperm passage through the egg coats C Barros, J Melendez, M Valdivia, M Rios, R Yunes Biological Research 26, 417-417, 1993 | 11 | 1993 |