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kenneth chien
kenneth chien
Dept of Cell and Molecular Biology, Karolinska Institutet
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Title
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Cited by
Year
PPARγ is required for placental, cardiac, and adipose tissue development
Y Barak, MC Nelson, ES Ong, YZ Jones, P Ruiz-Lozano, KR Chien, ...
Molecular cell 4 (4), 585-595, 1999
25021999
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages
KL Laugwitz, A Moretti, J Lam, P Gruber, Y Chen, S Woodard, LZ Lin, ...
Nature 433 (7026), 647-653, 2005
16612005
Signaling pathways for cardiac hypertrophy and failure
JJ Hunter, KR Chien
New England Journal of Medicine 341 (17), 1276-1283, 1999
12361999
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification
A Moretti, L Caron, A Nakano, JT Lam, A Bernshausen, Y Chen, Y Qyang, ...
Cell 127 (6), 1151-1165, 2006
12322006
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart
B Zhou, Q Ma, S Rajagopal, SM Wu, I Domian, J Rivera-Feliciano, ...
Nature 454 (7200), 109-113, 2008
11372008
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
Y Wang, S Huang, VP Sah, J Ross, JH Brown, J Han, KR Chien
Journal of Biological Chemistry 273 (4), 2161-2168, 1998
11061998
ErbB2 is essential in the prevention of dilated cardiomyopathy
SA Crone, YY Zhao, L Fan, Y Gu, S Minamisawa, Y Liu, KL Peterson, ...
Nature medicine 8 (5), 459-465, 2002
10472002
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy.
HA Rockman, RS Ross, AN Harris, KU Knowlton, ME Steinhelper, ...
Proceedings of the National Academy of Sciences 88 (18), 8277-8281, 1991
10311991
Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response
KR Chien, KU Knowlton, S Chien
The FASEB Journal 5 (15), 3037-3064, 1991
10081991
MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure
S Arber, JJ Hunter, J Ross, M Hongo, G Sansig, J Borg, JC Perriard, ...
Cell 88 (3), 393-403, 1997
10031997
Marked differences in differentiation propensity among human embryonic stem cell lines
K Osafune, L Caron, M Borowiak, RJ Martinez, CS Fitz-Gerald, Y Sato, ...
Nature biotechnology 26 (3), 313-315, 2008
9582008
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, ...
Nature immunology 4 (6), 551-556, 2003
9352003
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy
R Knöll, M Hoshijima, HM Hoffman, V Person, I Lorenzen-Schmidt, ...
Cell 111 (7), 943-955, 2002
9342002
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β2-Adrenergic Receptor
CA Milano, LF Allen, HA Rockman, PC Dolber, TR McMinn, KR Chien, ...
Science 264 (5158), 582-586, 1994
9281994
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ...
Nature medicine 20 (6), 616-623, 2014
8792014
Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43
DE Gutstein, GE Morley, H Tamaddon, D Vaidya, MD Schneider, J Chen, ...
Circulation research 88 (3), 333-339, 2001
8602001
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
H Hirota, J Chen, UAK Betz, K Rajewsky, Y Gu, J Ross, W Müller, ...
Cell 97 (2), 189-198, 1999
8421999
Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy.
D Pennica, KL King, KJ SHAw, E Luis, J Rullamas, SM LuOH, ...
Proceedings of the National Academy of Sciences 92 (4), 1142-1146, 1995
8061995
Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell …
HE Shubeita, PM McDonough, AN Harris, KU Knowlton, CC Glembotski, ...
Journal of Biological Chemistry 265 (33), 20555-20562, 1990
7861990
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.
HM Sucov, E Dyson, CL Gumeringer, J Price, KR Chien, RM Evans
Genes & development 8 (9), 1007-1018, 1994
7791994
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