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Jan Wenzel
Jan Wenzel
Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Germany
Adresse e-mail validée de pharma.uni-luebeck.de - Page d'accueil
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
J Wenzel, J Lampe, H Müller-Fielitz, R Schuster, M Zille, K Müller, ...
Nature neuroscience 24 (11), 1522-1533, 2021
2102021
A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases
J Körbelin, G Dogbevia, S Michelfelder, DA Ridder, A Hunger, J Wenzel, ...
EMBO molecular medicine 8 (6), 609-625, 2016
1872016
Organotypic slice culture from human adult ventricular myocardium
M Brandenburger, J Wenzel, R Bogdan, D Richardt, F Nguemo, M Reppel, ...
Cardiovascular research 93 (1), 50-59, 2012
1312012
Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes
N Perwitz, J Wenzel, I Wagner, J Büning, M Drenckhan, K Zarse, M Ristow, ...
Diabetes, Obesity and Metabolism 12 (2), 158-166, 2010
1272010
Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis
H Müller-Fielitz, M Stahr, M Bernau, M Richter, S Abele, V Krajka, ...
Nature communications 8 (1), 484, 2017
902017
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit
DA Ridder, J Wenzel, K Müller, K Töllner, XK Tong, JC Assmann, ...
Journal of Experimental Medicine 212 (10), 1529-1549, 2015
802015
The impact of endothelial cell death in the brain and its role after stroke: a systematic review
M Zille, M Ikhsan, Y Jiang, J Lampe, J Wenzel, M Schwaninger
Cell stress 3 (11), 330, 2019
592019
Hypocretin/orexin increases the expression of steroidogenic enzymes in human adrenocortical NCI H295R cells
J Wenzel, N Grabinski, CA Knopp, A Dendorfer, M Ramanjaneya, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009
552009
Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice
J Wenzel, CE Hansen, C Bettoni, MA Vogt, B Lembrich, R Natsagdorj, ...
Proceedings of the National Academy of Sciences 117 (3), 1753-1761, 2020
482020
Isolation and cultivation of primary brain endothelial cells from adult mice
JC Assmann, K Müller, J Wenzel, T Walther, J Brands, P Thornton, ...
Bio-protocol 7 (10), e2294-e2294, 2017
462017
NF-κB signaling in tanycytes mediates inflammation-induced anorexia
M Böttcher, H Müller-Fielitz, SM Sundaram, S Gallet, V Neve, K Shionoya, ...
Molecular metabolism 39, 101022, 2020
322020
Thrombomodulin–a new target for treating stroke at the crossroad of coagulation and inflammation
J Wenzel, JC Assmann, M Schwaninger
Current medicinal chemistry 21 (18), 2025-2034, 2014
322014
Gene therapy decreases seizures in a model of Incontinentia pigmenti
GK Dogbevia, K Töllner, J Körbelin, S Bröer, DA Ridder, H Grasshoff, ...
Annals of Neurology 82 (1), 93-104, 2017
272017
Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels
E Cecon, D Fernandois, N Renault, CFF Coelho, J Wenzel, C Bedart, ...
Cellular and Molecular Life Sciences 79 (7), 361, 2022
212022
Telmisartan prevents high-fat diet-induced neurovascular impairments and reduces anxiety-like behavior
G Huber, M Ogrodnik, J Wenzel, I Stölting, L Huber, O Will, E Peschke, ...
Journal of Cerebral Blood Flow & Metabolism 41 (9), 2356-2369, 2021
172021
Endogenous THBD (Thrombomodulin) mediates angiogenesis in the ischemic brain—brief report
J Wenzel, D Spyropoulos, JC Assmann, MA Khan, I Stölting, B Lembrich, ...
Arteriosclerosis, thrombosis, and vascular biology 40 (12), 2837-2844, 2020
172020
In vitro Developed Spontaneously Contracting Cardiomyocytes from Rainbow Trout as a Model System for Human Heart Research
B Grunow, J Wenzel, H Terlau, S Langner, M Gebert, C Kruse
Cellular Physiology and Biochemistry 27 (1), 1-12, 2011
142011
How COVID-19 affects microvessels in the brain
J Wenzel, M Schwaninger
Brain 145 (7), 2242-2244, 2022
72022
Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease
Y Jiang, K Müller, MA Khan, JC Assmann, J Lampe, K Kilau, M Richter, ...
Journal of Cerebral Blood Flow & Metabolism 41 (2), 219-235, 2021
72021
Die Blut-Hirn-Schranke und ihre Regulation durch NF-κB-Signalwege
J Wenzel, M Schwaninger
e-Neuroforum 22 (2), 33-44, 2016
52016
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