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Micael Hardy
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Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
J Zielonka, J Joseph, A Sikora, M Hardy, O Ouari, J Vasquez-Vivar, ...
Chemical reviews 117 (15), 10043-10120, 2017
12032017
Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides
J Zielonka, A Sikora, M Hardy, J Joseph, BP Dranka, B Kalyanaraman
Chemical research in toxicology 25 (9), 1793-1799, 2012
2472012
A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic …
B Kalyanaraman, G Cheng, M Hardy, O Ouari, M Lopez, J Joseph, ...
Redox biology 14, 316-327, 2018
2122018
Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies
B Kalyanaraman, G Cheng, M Hardy, O Ouari, B Bennett, J Zielonka
Redox biology 15, 347-362, 2018
2052018
Global profiling of reactive oxygen and nitrogen species in biological systems
J Zielonka, M Zielonka, A Sikora, J Adamus, J Joseph, M Hardy, O Ouari, ...
Journal of Biological Chemistry 287 (5), 2984-2995, 2012
1922012
Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells
G Cheng, J Zielonka, O Ouari, M Lopez, D McAllister, K Boyle, CS Barrios, ...
Cancer research 76 (13), 3904-3915, 2016
1882016
HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements
J Zielonka, M Hardy, B Kalyanaraman
Free Radical Biology and Medicine 46 (3), 329-338, 2009
1712009
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
G Cheng, Q Zhang, J Pan, Y Lee, O Ouari, M Hardy, M Zielonka, ...
Nature communications 10 (1), 2205, 2019
1632019
HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes—the ultimate approach for intra-and extracellular superoxide detection
B Kalyanaraman, BP Dranka, M Hardy, R Michalski, J Zielonka
Biochimica Et Biophysica Acta (BBA)-General Subjects 1840 (2), 739-744, 2014
1362014
Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo-and heterodimers
J Zielonka, S Srinivasan, M Hardy, O Ouari, M Lopez, J Vasquez-Vivar, ...
Free Radical Biology and Medicine 44 (5), 835-846, 2008
1272008
Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling
B Kalyanaraman, M Hardy, R Podsiadly, G Cheng, J Zielonka
Archives of biochemistry and biophysics 617, 38-47, 2017
1262017
Comprehensive Synthesis of Monohydroxy–Cucurbit[n]urils (n = 5, 6, 7, 8): High Purity and High Conversions
MM Ayhan, H Karoui, M Hardy, A Rockenbauer, L Charles, R Rosas, ...
Journal of the American Chemical Society 137 (32), 10238-10245, 2015
1242015
Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future
G Cheng, M Zielonka, B Dranka, SN Kumar, CR Myers, B Bennett, ...
Journal of Biological Chemistry 293 (26), 10363-10380, 2018
982018
Detection of superoxide production in stimulated and unstimulated living cells using new cyclic nitrone spin traps
K Abbas, M Hardy, F Poulhès, H Karoui, P Tordo, O Ouari, F Peyrot
Free Radical Biology and Medicine 71, 281-290, 2014
892014
Detection and characterization of reactive oxygen and nitrogen species in biological systems by monitoring species-specific products
M Hardy, J Zielonka, H Karoui, A Sikora, R Michalski, R Podsiadły, ...
Antioxidants & redox signaling 28 (15), 1416-1432, 2018
882018
Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism
G Cheng, J Zielonka, D McAllister, M Hardy, O Ouari, J Joseph, ...
Cancer letters 365 (1), 96-106, 2015
832015
Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap
M Hardy, A Rockenbauer, J Vásquez-Vivar, C Felix, M Lopez, ...
Chemical research in toxicology 20 (7), 1053-1060, 2007
782007
Mitigation of NADPH oxidase 2 activity as a strategy to inhibit peroxynitrite formation
J Zielonka, M Zielonka, L VerPlank, G Cheng, M Hardy, O Ouari, ...
Journal of Biological Chemistry 291 (13), 7029-7044, 2016
642016
Toward selective detection of reactive oxygen and nitrogen species with the use of fluorogenic probes—Limitations, progress, and perspectives
K Debowska, D Debski, M Hardy, M Jakubowska, B Kalyanaraman, ...
Pharmacological Reports 67, 756-764, 2015
592015
Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide
R Michalski, J Zielonka, M Hardy, J Joseph, B Kalyanaraman
Free Radical Biology and Medicine 54, 135-147, 2013
532013
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