Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome FC Bronfman, M Tcherpakov, TM Jovin, M Fainzilber Journal of Neuroscience 23 (8), 3209-3220, 2003 | 237 | 2003 |
Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord I Tesseur, J Van Dorpe, K Bruynseels, F Bronfman, R Sciot, ... The American journal of pathology 157 (5), 1495-1510, 2000 | 175 | 2000 |
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-α-converting enzyme/ADAM17 RS Kenchappa, C Tep, Z Korade, S Urra, FC Bronfman, SO Yoon, ... Journal of biological chemistry 285 (26), 20358-20368, 2010 | 164 | 2010 |
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann‐Pick type C disease AR Alvarez, A Klein, J Castro, GI Cancino, J Amigo, M Mosqueira, ... The FASEB Journal 22 (10), 3617-3627, 2008 | 162 | 2008 |
Cellular and molecular mechanisms regulating neuronal growth by brain‐derived neurotrophic factor A Gonzalez, G Moya‐Alvarado, C Gonzalez‐Billaut, FC Bronfman Cytoskeleton 73 (10), 612-628, 2016 | 159 | 2016 |
BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching OM Lazo, A Gonzalez, M Ascano, R Kuruvilla, A Couve, FC Bronfman Journal of Neuroscience 33 (14), 6112-6122, 2013 | 154 | 2013 |
Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases FC Bronfman, CA Escudero, J Weis, A Kruttgen Developmental neurobiology 67 (9), 1183-1203, 2007 | 145 | 2007 |
TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal γ-secretase-mediated release of the p75 intracellular domain S Urra, CA Escudero, P Ramos, F Lisbona, E Allende, P Covarrubias, ... Journal of biological chemistry 282 (10), 7606-7615, 2007 | 127 | 2007 |
The p75 neurotrophin receptor interacts with multiple MAGE proteins M Tcherpakov, FC Bronfman, SG Conticello, A Vaskovsky, Z Levy, ... Journal of Biological Chemistry 277 (51), 49101-49104, 2002 | 125 | 2002 |
Multi‐tasking by the p75 neurotrophin receptor: sortilin things out? FC Bronfman, M Fainzilber EMBO reports 5 (9), 867-871, 2004 | 118 | 2004 |
Neurodegeneration and Alzheimer's disease (AD). What can proteomics tell us about the Alzheimer's brain? G Moya-Alvarado, N Gershoni-Emek, E Perlson, FC Bronfman Molecular & Cellular Proteomics 15 (2), 409-425, 2016 | 116 | 2016 |
Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice FC Bronfman, D Moechars, F Van Leuven Neurobiology of disease 7 (3), 152-168, 2000 | 109 | 2000 |
Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-β-peptides A Alvarez, F Bronfman, CA Pérez, M Vicente, J Garrido, NC Inestrosa Neuroscience letters 201 (1), 49-52, 1995 | 92 | 1995 |
ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the … RA Fuentealba, MI Barría, J Lee, J Cam, C Araya, CA Escudero, ... Molecular neurodegeneration 2, 1-19, 2007 | 84 | 2007 |
Laminin inhibits amyloid-β-peptide fibrillation FC Bronfman, J Garrido, A Alvarez, C Morgan, NC Inestrosa Neuroscience letters 218 (3), 201-203, 1996 | 82 | 1996 |
The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release CA Escudero, OM Lazo, C Galleguillos, JI Parraguez, MA Lopez-Verrilli, ... Journal of Cell Science 127 (9), 1966-1979, 2014 | 67 | 2014 |
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis DE Hernández, NA Salvadores, G Moya-Alvarado, RJ Catalán, ... Journal of Cell Science 131 (22), jcs214684, 2018 | 65 | 2018 |
Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production P Langjahr, D Díaz-Jiménez, M De la Fuente, E Rubio, D Golenbock, ... PloS one 9 (12), e104624, 2014 | 57 | 2014 |
Spatiotemporal intracellular dynamics of neurotrophin and its receptors. Implications for neurotrophin signaling and neuronal function FC Bronfman, OM Lazo, C Flores, CA Escudero Neurotrophic factors, 33-65, 2014 | 56 | 2014 |
Rab GTPase signaling in neurite outgrowth and axon specification D Villarroel‐Campos, FC Bronfman, C Gonzalez‐Billault Cytoskeleton 73 (9), 498-507, 2016 | 55 | 2016 |