| Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database P Møller, T Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ... Gut 66 (3), 464-472, 2017 | 548 | 2017 |
| Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database P Møller, TT Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ... Gut 67 (7), 1306-1316, 2018 | 544 | 2018 |
| Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database M Dominguez-Valentin, JR Sampson, TT Seppälä, SW Ten Broeke, ... Genetics in Medicine 22 (1), 15-25, 2020 | 500 | 2020 |
| Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland … KJ Monahan, N Bradshaw, S Dolwani, B Desouza, MG Dunlop, JE East, ... Gut 69 (3), 411-444, 2020 | 343 | 2020 |
| Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind … J Burn, H Sheth, F Elliott, L Reed, F Macrae, JP Mecklin, G Möslein, ... The Lancet 395 (10240), 1855-1863, 2020 | 295 | 2020 |
| CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings TT Seppälä, O Nerg, AM Koivisto, J Rummukainen, L Puli, H Zetterberg, ... Neurology 78 (20), 1568-1575, 2012 | 267 | 2012 |
| Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer TT Seppälä, JP Böhm, M Friman, L Lahtinen, VMJ Väyrynen, TKE Liipo, ... British journal of cancer 112 (12), 1966-1975, 2015 | 168 | 2015 |
| European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender TT Seppälä, A Latchford, I Negoi, A Sampaio Soares, ... British Journal of Surgery 108 (5), 484-498, 2021 | 157 | 2021 |
| Characteristics of early-onset vs late-onset colorectal cancer: a review R Collaborative, AM Zaborowski, A Abdile, M Adamina, F Aigner, ... JAMA surgery 156 (9), 865-874, 2021 | 155 | 2021 |
| Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database P Møller, T Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ... Gut 66 (9), 1657-1664, 2017 | 149 | 2017 |
| No difference in colorectal cancer incidence or stage at detection by colonoscopy among 3 countries with different Lynch syndrome surveillance policies C Engel, HF Vasen, T Seppälä, S Aretz, M Bigirwamungu-Bargeman, ... Gastroenterology 155 (5), 1400-1409. e2, 2018 | 130 | 2018 |
| Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus OT Pyykkö, M Lumela, J Rummukainen, O Nerg, TT Seppälä, SK Herukka, ... PloS one 9 (3), e91974, 2014 | 120 | 2014 |
| Plasma Aβ42 and Aβ40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study TT Seppälä, SK Herukka, T Hänninen, S Tervo, M Hallikainen, H Soininen, ... Journal of Neurology, Neurosurgery & Psychiatry 81 (10), 1123-1127, 2010 | 116 | 2010 |
| The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ... Nature communications 11 (1), 4740, 2020 | 104 | 2020 |
| Genetic and epigenetic characteristics of inflammatory bowel Disease–Associated colorectal cancer K Rajamäki, A Taira, R Katainen, N Välimäki, A Kuosmanen, RM Plaketti, ... Gastroenterology 161 (2), 592-607, 2021 | 99 | 2021 |
| Longitudinal changes of CSF biomarkers in Alzheimer's disease TT Seppälä, AM Koivisto, P Hartikainen, S Helisalmi, H Soininen, ... Journal of Alzheimer's Disease 25 (4), 583-594, 2011 | 91 | 2011 |
| Immunoscore in mismatch repair‐proficient and‐deficient colon cancer EV Wirta, T Seppälä, M Friman, J Väyrynen, M Ahtiainen, H Kautiainen, ... The Journal of Pathology: Clinical Research 3 (3), 203-213, 2017 | 78 | 2017 |
| Patient-derived organoid pharmacotyping is a clinically tractable strategy for precision medicine in pancreatic cancer TT Seppälä, JW Zimmerman, E Sereni, D Plenker, R Suri, N Rozich, ... Annals of surgery 272 (3), 427-435, 2020 | 72 | 2020 |
| Associations of pathogenic variants in MLH1, MSH2, and MSH6 with risk of colorectal adenomas and tumors and with somatic mutations in patients with Lynch syndrome C Engel, A Ahadova, TT Seppälä, S Aretz, M Bigirwamungu-Bargeman, ... Gastroenterology 158 (5), 1326-1333, 2020 | 71 | 2020 |
| Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report T Seppälä, K Pylvänäinen, DG Evans, H Järvinen, L Renkonen-Sinisalo, ... Hereditary cancer in clinical practice 15, 1-10, 2017 | 70 | 2017 |
Juha P. VäyrynenUniversity of OuluVerified email at oulu.fi
