| Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase BL Montalvo-Ortiz, L Castillo-Pichardo, E Hernández, ... Journal of Biological Chemistry 287 (16), 13228-13238, 2012 | 233 | 2012 |
| Smaller Substituents on Nitrogen Facilitate the Osmium‐Catalyzed Asymmetric Aminohydroxylation J Rudolph, PC Sennhenn, CP Vlaar, KB Sharpless Angewandte Chemie International Edition in English 35 (23‐24), 2810-2813, 1996 | 137 | 1996 |
| Characterization of a dual Rac/Cdc42 inhibitor MBQ-167 in metastatic cancer T Humphries-Bickley, L Castillo-Pichardo, E Hernandez-O’Farrill, ... Molecular cancer therapeutics 16 (5), 805-818, 2017 | 78 | 2017 |
| The Rac inhibitor EHop-016 inhibits mammary tumor growth and metastasis in a nude mouse model L Castillo-Pichardo, T Humphries-Bickley, C De La Parra, ... Translational oncology 7 (5), 546-555, 2014 | 78 | 2014 |
| Synthesis of 1, 4-dihydro-benzo [d][1, 3] oxazin-2-ones from phthalides via an aminolysis-Hofmann rearrangement protocol E Hernández, JM Vélez, CP Vlaar Tetrahedron letters 48 (51), 8972-8975, 2007 | 57 | 2007 |
| Pak and Rac GTPases promote oncogenic KIT–induced neoplasms H Martin, RS Mali, P Ma, A Chatterjee, B Ramdas, E Sims, ... The Journal of clinical investigation 123 (10), 4449-4463, 2013 | 48 | 2013 |
| Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: evidence for a requisite role of Ras-related C3 botulinum … V Sidarala, R Veluthakal, K Syeda, C Vlaar, P Newsholme, A Kowluru Biochemical pharmacology 95 (4), 301-310, 2015 | 44 | 2015 |
| Synthesis of phosphonate and thiophosphonate esters and amides from hydrogen-phosphinates by a novel one-pot activation-coupling-oxidation procedure MF Fernandez, CP Vlaar, H Fan, YH Liu, FR Fronczek, RP Hammer The Journal of Organic Chemistry 60 (23), 7390-7391, 1995 | 44 | 1995 |
| Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents CP Vlaar, L Castillo-Pichardo, JI Medina, CM Marrero-Serra, E Vélez, ... Bioorganic & medicinal chemistry 26 (4), 884-890, 2018 | 43 | 2018 |
| VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells R Veluthakal, R Tunduguru, DK Arora, V Sidarala, K Syeda, CP Vlaar, ... Diabetologia 58, 2573-2581, 2015 | 41 | 2015 |
| Novel inhibitors of Rac1 in metastatic breast cancer E Hernández, A De La Mota-Peynado, S Dharmawardhane, CP Vlaar Puerto Rico health sciences journal 29 (4), 2010 | 41 | 2010 |
| Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry T Humphries-Bickley, L Castillo-Pichardo, F Corujo-Carro, J Duconge, ... Journal of Chromatography B 981, 19-26, 2015 | 33 | 2015 |
| Development of EHop-016: a small molecule inhibitor of Rac S Dharmawardhane, E Hernandez, C Vlaar The enzymes 33, 117-146, 2013 | 31 | 2013 |
| Osmiumkatalysierte asymmetrische Aminohydroxylierung: kleinere Substituenten am Stickstoffatom erleichtern die Reaktion J Rudolph, PC Sennhenn, CP Vlaar, KB Sharpless Angewandte Chemie 108 (23‐24), 2991-2995, 1996 | 24 | 1996 |
| Preparation and some properties of 7, 7-dilithionorbornane CP Vlaar, GW Klumpp Tetrahedron letters 32 (25), 2951-2952, 1991 | 16 | 1991 |
| Efficacy of Rac and Cdc42 inhibitor MBQ-167 in triple-negative breast cancer A Cruz-Collazo, JF Ruiz-Calderon, H Picon, LD Borrero-Garcia, I Lopez, ... Molecular cancer therapeutics 20 (12), 2420-2432, 2021 | 15 | 2021 |
| Pharmacokinetics of the Rac/Cdc42 Inhibitor MBQ-167 in Mice by Supercritical Fluid Chromatography–Tandem Mass Spectrometry MM Maldonado, G Rosado-González, J Bloom, J Duconge, ... ACS omega 4 (19), 17981-17989, 2019 | 13 | 2019 |
| Small-molecule inhibitors of Rac1 in metastatic breast cancer E Hernandez, C Vlaar, S Dharmawardhane US Patent 8,884,006, 2014 | 11 | 2014 |
| Small-molecule inhibitors of Rac1 in metastatic cancer cells E Hernandez, C Vlaar, S Dharmawardhane US Patent 9,278,956, 2016 | 9 | 2016 |
| Reduction of Geminal Dihalocyclopropanes with Lithium 4,4′‐Di‐tert‐butylbiphenyl; Cyclopropyl Derivatives of Dilithiomethane and 1,2‐Dilithioethane; Inferences … CP Vlaar, GW Klumpp Angewandte Chemie International Edition in English 32 (4), 574-576, 1993 | 9 | 1993 |
