Cytotoxicity of lapachol, β-lapachone and related synthetic 1, 4-naphthoquinones against oesophageal cancer cells SN Sunassee, CGL Veale, N Shunmoogam-Gounden, O Osoniyi, ... European Journal of Medicinal Chemistry 62, 98-110, 2013 | 80 | 2013 |
Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro JA de la Mare, JC Lawson, MT Chiwakata, DR Beukes, AL Edkins, ... Investigational New Drugs 30, 2187-2200, 2012 | 75 | 2012 |
Breast cancer: current developments in molecular approaches to diagnosis and treatment JA de la Mare, L Contu, M C Hunter, B Moyo, J N Sterrenberg, ... Recent patents on anti-cancer drug discovery 9 (2), 153-175, 2014 | 70 | 2014 |
Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay JA de la Mare, JN Sterrenberg, MG Sukhthankar, MT Chiwakata, ... Cancer Cell International 13, 1-14, 2013 | 53 | 2013 |
Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model JA de la Mare, T Jurgens, AL Edkins BMC cancer 17, 1-16, 2017 | 45 | 2017 |
The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells S Aliwaini, J Peres, WL Kröger, A Blanckenberg, J de La Mare, AL Edkins, ... Cancer Letters 357 (1), 206-218, 2015 | 40 | 2015 |
In vitro analysis of putative cancer stem cell populations and chemosensitivity in the SW480 and SW620 colon cancer metastasis model C Slater, JA de La Mare, AL Edkins Oncology letters 15 (6), 8516-8526, 2018 | 32 | 2018 |
Ruthenium complexes with mono- or bis-heterocyclic chelates: DNA/BSA binding, antioxidant and anticancer studies S Maikoo, A Chakraborty, N Vukea, LMK Dingle, WJ Samson, ... Journal of Biomolecular Structure and Dynamics 39 (11), 4077-4088, 2021 | 31 | 2021 |
Novobiocin–ferrocene conjugates possessing anticancer and antiplasmodial activity independent of HSP90 inhibition M Mbaba, JA de la Mare, JN Sterrenberg, D Kajewole, S Maharaj, ... JBIC Journal of Biological Inorganic Chemistry 24, 139-149, 2019 | 26 | 2019 |
Isolation, Characterization and Antiproliferative Activity of New Metabolites from the South African Endemic Red Algal Species Laurencia alfredensis GA Dziwornu, MR Caira, JA de la Mare, AL Edkins, JJ Bolton, DR Beukes, ... Molecules 22 (4), 513, 2017 | 23 | 2017 |
Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties L Gramni, N Vukea, A Chakraborty, WJ Samson, LMK Dingle, B Xulu, ... Inorganica Chimica Acta 492, 98-107, 2019 | 21 | 2019 |
Repurposing a polymer precursor: Synthesis and in vitro medicinal potential of ferrocenyl 1, 3-benzoxazine derivatives M Mbaba, LMK Dingle, D Cash, JA de la Mare, D Laming, D Taylor, ... European Journal of Medicinal Chemistry 187, 111924, 2020 | 20 | 2020 |
In vitro and in vivo toxicity assessment of biologically synthesized silver nanoparticles from Elaeodendron croceum SW Odeyemi, J De La Mare, AL Edkins, AJ Afolayan Journal of Complementary and Integrative Medicine 16 (3), 20180184, 2019 | 17 | 2019 |
The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity S Kimani, S Chakraborty, I Irene, J de la Mare, A Edkins, A du Toit, B Loos, ... Biochemical Pharmacology 190, 114598, 2021 | 15 | 2021 |
Coumarin-annulated ferrocenyl 1, 3-oxazine derivatives possessing in vitro antimalarial and antitrypanosomal potency M Mbaba, LMK Dingle, AI Zulu, D Laming, T Swart, JA de la Mare, ... Molecules 26 (5), 1333, 2021 | 15 | 2021 |
Heterodimer formation by Oct4 and Smad3 differentially regulates epithelial-to-mesenchymal transition-associated factors in breast cancer progression G Mandal, S Biswas, SR Chowdhury, A Chatterjee, S Purohit, P Khamaru, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (6 …, 2018 | 11 | 2018 |
STIP1/HOP regulates the actin cytoskeleton through interactions with actin and changes in actin-binding proteins cofilin and profilin SJ Beckley, MC Hunter, SN Kituyi, I Wingate, A Chakraborty, K Schwarz, ... International Journal of Molecular Sciences 21 (9), 3152, 2020 | 10 | 2020 |
Facile synthesis and biological evaluation of assorted indolyl-3-amides and esters from a single, stable carbonyl nitrile intermediate CGL Veale, AL Edkins, JA de la Mare, C de Kock, PJ Smith, SD Khanye Tetrahedron letters 56 (14), 1860-1864, 2015 | 10 | 2015 |
Halogenated oxindole and indoles from the South African marine ascidian Distaplia skoogi CL Bromley, S Parker-Nance, JA de la Mare, AL Edkins, DR Beukes, ... South African Journal of Chemistry 66, 00-00, 2013 | 9 | 2013 |
The in Vitro Antiplasmodial and Antiproliferative Activity of New Ferrocene‐Based α‐Aminocresols Targeting Hemozoin Inhibition and DNA Interaction M Mbaba, LMK Dingle, T Swart, D Cash, D Laming, JA de la Mare, ... ChemBioChem 21 (18), 2643-2658, 2020 | 8 | 2020 |