Conjugation to poly (amidoamine) dendrimers and pulmonary delivery reduce cardiac accumulation and enhance antitumor activity of doxorubicin in lung metastasis Q Zhong, ER Bielski, LS Rodrigues, MR Brown, JJ Reineke, ... Molecular pharmaceutics 13 (7), 2363-2375, 2016 | 92 | 2016 |
Effect of the conjugation density of triphenylphosphonium cation on the mitochondrial targeting of poly (amidoamine) dendrimers ER Bielski, Q Zhong, M Brown, SRP da Rocha Molecular pharmaceutics 12 (8), 3043-3053, 2015 | 75 | 2015 |
TPP-dendrimer nanocarriers for siRNA delivery to the pulmonary epithelium and their dry powder and metered-dose inhaler formulations E Bielski, Q Zhong, H Mirza, M Brown, A Molla, T Carvajal, SRP da Rocha International journal of pharmaceutics 527 (1-2), 171-183, 2017 | 65 | 2017 |
A method for the generation of human stem cell-derived alpha cells QP Peterson, A Veres, L Chen, MQ Slama, JHR Kenty, S Hassoun, ... Nature communications 11 (1), 2241, 2020 | 64 | 2020 |
Specialized mechanosensory epithelial cells in mouse gut intrinsic tactile sensitivity AJ Treichel, I Finholm, KR Knutson, C Alcaino, ST Whiteman, MR Brown, ... Gastroenterology 162 (2), 535-547. e13, 2022 | 46 | 2022 |
Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes N Javeed, TK Her, MR Brown, P Vanderboom, K Rakshit, AM Egan, ... Cell reports 36 (8), 2021 | 33 | 2021 |
Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function MR Brown, SK Sen, A Mazzone, TK Her, Y Xiong, JH Lee, N Javeed, ... Science advances 7 (51), eabg6856, 2021 | 26 | 2021 |
Proinflammatory cytokine interleukin 1β disrupts β-cell circadian clock function and regulation of insulin secretion N Javeed, MR Brown, K Rakshit, T Her, SK Sen, AV Matveyenko Endocrinology 162 (1), bqaa084, 2021 | 23 | 2021 |
Dietary carbohydrates modulate metabolic and β-cell adaptation to high-fat diet-induced obesity TK Her, WS Lagakos, MR Brown, NK LeBrasseur, K Rakshit, ... American Journal of Physiology-Endocrinology and Metabolism 318 (6), E856-E865, 2020 | 19 | 2020 |
Functional and transport analyses of CLCN5 genetic changes identified in Dent disease patients X Tang, MR Brown, AG Cogal, D Gauvin, PC Harris, JC Lieske, ... Physiological reports 4 (8), e12776, 2016 | 19 | 2016 |
Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment L Ruiz, T Gurlo, MA Ravier, A Wojtusciszyn, J Mathieu, MR Brown, ... Cell death & disease 9 (6), 600, 2018 | 18 | 2018 |
Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic β cell function in type 2 diabetes MR Brown, H Holmes, K Rakshit, N Javeed, TK Her, AA Stiller, S Sen, ... The Journal of Clinical Investigation 131 (17), 2021 | 14 | 2021 |
Cl− and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl−/H+ exchanger ClC-5 MH Chang, MR Brown, Y Liu, VG Gainullin, PC Harris, MF Romero, ... Journal of Biological Chemistry 295 (6), 1464-1473, 2020 | 12 | 2020 |
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity N Wieder, JC Fried, C Kim, EH Sidhom, MR Brown, JL Marshall, ... Cell metabolism 35 (5), 887-905. e11, 2023 | 7 | 2023 |
It’s what and when you eat: an overview of transcriptional and epigenetic responses to dietary perturbations in pancreatic islets MR Brown, AV Matveyenko Frontiers in Endocrinology 13, 842603, 2022 | 7 | 2022 |
The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions MR Brown, D Laouteouet, M Delobel, O Villard, C Broca, G Bertrand, ... Cell Death & Disease 13 (4), 353, 2022 | 6 | 2022 |
Biological Timekeeping: Scientific Background MR Brown, AV Matveyenko Circadian Rhythm Sleep-Wake Disorders, 1-20, 2020 | 2 | 2020 |
Pro-inflammatory cytokines disrupt β-cell circadian clocks in diabetes N Javeed, MR Brown, K Rakshit, T Her, Z Ye, JH Lee, T Ordog, ... bioRxiv, 705210, 2019 | 2 | 2019 |
Physiological glucocorticoid replacement in adrenal insufficiency: does it fix the broken clock? MR Brown, AV Matveyenko The Journal of Clinical Endocrinology & Metabolism 103 (9), 3511-3513, 2018 | 2 | 2018 |
2109-P: Type 2 Diabetic Human Beta Cells Are Characterized by Marked Expression of the Na+-nHCO3-Cotransporter NBCe1 and Intracellular Alkalization M Brown, A Stiller, MF Romero, A Matveyenko Diabetes 69 (Supplement_1), 2020 | 1 | 2020 |