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Gaurav Bhardwaj
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Accurate de novo design of hyperstable constrained peptides
G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ...
Nature 538 (7625), 329-335, 2016
3862016
Comprehensive computational design of ordered peptide macrocycles
P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ...
Science 358 (6369), 1461-1466, 2017
1652017
Accurate de novo design of membrane-traversing macrocycles
G Bhardwaj, J O’Connor, S Rettie, YH Huang, TA Ramelot, VK Mulligan, ...
Cell 185 (19), 3520-3532. e26, 2022
572022
Phylogenetic profiles reveal evolutionary relationships within the “twilight zone” of sequence similarity
GS Chang, Y Hong, KD Ko, G Bhardwaj, EC Holmes, RL Patterson, ...
Proceedings of the National Academy of Sciences 105 (36), 13474, 2008
562008
Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor
W Guo, R Liu, G Bhardwaj, JC Yang, C Changou, AH Ma, A Mazloom, ...
Cell death & disease 5 (9), e1409-e1409, 2014
502014
Reevaluation of the evolutionary events within recA/RAD51 phylogeny
SV Chintapalli, G Bhardwaj, J Babu, L Hadjiyianni, Y Hong, GK Todd, ...
BMC genomics 14, 1-10, 2013
372013
TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion
DB van Rossum, D Oberdick, Y Rbaibi, G Bhardwaj, RK Barrow, ...
Journal of Biological Chemistry 283 (49), 34384-34392, 2008
362008
A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo
TC Shih, R Liu, G Fung, G Bhardwaj, PM Ghosh, KS Lam
Molecular cancer therapeutics 16 (7), 1212-1223, 2017
352017
Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A
G Kaplan, F Lee, M Onda, E Kolyvas, G Bhardwaj, D Baker, I Pastan
Toxins 8 (8), 217, 2016
322016
Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin
SV Chintapalli, G Bhardwaj, R Patel, N Shah, RL Patterson, ...
PloS one 10 (6), e0128496, 2015
292015
Covalent chemical ligation strategy for mono-and polyclonal immunoglobulins at their nucleotide binding sites
D Lac, C Feng, G Bhardwaj, H Le, J Tran, L Xing, G Fung, R Liu, H Cheng, ...
Bioconjugate chemistry 27 (1), 159-169, 2016
262016
PHYRN: a robust method for phylogenetic analysis of highly divergent sequences
G Bhardwaj, KD Ko, Y Hong, Z Zhang, NL Ho, SV Chintapalli, LA Kline, ...
PLoS One 7 (4), e34261, 2012
222012
Cyclic peptide structure prediction and design using AlphaFold
SA Rettie, KV Campbell, AK Bera, A Kang, S Kozlov, J De La Cruz, ...
bioRxiv, 2023
172023
Phylogenetic profiles reveal structural and functional determinants of lipid-binding
Y Hong, D Chalkia, KD Ko, G Bhardwaj, GS Chang, DB van Rossum, ...
Journal of proteomics & bioinformatics 2, 139, 2009
172009
Phylogenetic profiles as a unified framework for measuring protein structure, function and evolution
KD Ko, Y Hong, GS Chang, G Bhardwaj, DB Van Rossum, RL Patterson
Arxiv preprint arXiv:0806.2394, 2008
162008
Exploring phospholipase C-coupled Ca21 signalling networks using boolean modelling
G Bhardwaj, CP Wells, R Albert, DB van Rossum, RL Patterson
Systems Biology, IET 5 (3), 174-184, 2011
132011
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors
W Guo, R Liu, G Bhardwaj, AH Ma, C Changou, JC Yang, Y Li, C Feng, ...
PLoS One 8 (8), e70910, 2013
102013
Predicting Protein Folds with Fold-Specific PSSM Libraries
Y Hong, SV Chintapalli, KD Ko, G Bhardwaj, Z Zhang, D van Rossum, ...
PloS one 6 (6), e20557, 2011
82011
Brainstorming through the sequence universe: theories on the protein problem
KD Ko, Y Hong, G Bhardwaj, TM Killick, DB Van Rossum, RL Patterson
Arxiv preprint arXiv:0911.0652, 2009
82009
ITK inhibition for the targeted treatment of CTCL
I Bustos-Villalobos, JW Bergstrom, NE Haigh, JI Luna, A Mitra, ...
Journal of dermatological science 87 (1), 88-91, 2017
72017
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