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Dilip Narayanan
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Year
A comparative assessment study of known small-molecule Keap1− Nrf2 protein–protein interaction inhibitors: chemical synthesis, binding properties, and cellular activity
KT Tran, JS Pallesen, SMØ Solbak, D Narayanan, A Baig, J Zang, ...
Journal of medicinal chemistry 62 (17), 8028-8052, 2019
722019
Targeting the redox landscape in cancer therapy
D Narayanan, S Ma, D Özcelik
Cancers 12 (7), 1706, 2020
352020
Deconstructing noncovalent Kelch-like ECH-associated protein 1 (Keap1) inhibitors into fragments to reconstruct new potent compounds
JS Pallesen, D Narayanan, KT Tran, SMØ Solbak, G Marseglia, ...
Journal of medicinal chemistry 64 (8), 4623-4661, 2021
312021
Developing inhibitors of the p47phox–p22phox protein–protein interaction by fragment-based drug discovery
SMØ Solbak, J Zang, D Narayanan, LJ Høj, S Bucciarelli, C Softley, ...
Journal of Medicinal Chemistry 63 (3), 1156-1177, 2020
272020
Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches
OA Gani, B Thakkar, D Narayanan, KA Alam, P Kyomuhendo, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (10), 1605-1616, 2015
182015
Development of noncovalent small-molecule Keap1-Nrf2 inhibitors by fragment-based drug discovery
D Narayanan, KT Tran, JS Pallesen, SMØ Solbak, Y Qin, E Mukminova, ...
Journal of medicinal chemistry 65 (21), 14481-14526, 2022
152022
Evaluating the Predictivity of Virtual Screening for A bl Kinase Inhibitors to Hinder Drug Resistance
OA Gani, D Narayanan, RA Engh
Chemical Biology & Drug Design 82 (5), 506-519, 2013
122013
Small-molecule modulators of tumor necrosis factor signaling
H Chédotal, D Narayanan, K Povlsen, CH Gotfredsen, R Brambilla, ...
Drug discovery today, 103575, 2023
72023
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR
D Narayanan, OA Gani, FXE Gruber, RA Engh
Journal of Cheminformatics 9, 1-19, 2017
42017
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking and kinase inhibition
D Narayanan, ASG Larsen, SJ Gauger, R Adafia, RB Hammershøi, ...
bioRxiv, 2024.03. 26.586665, 2024
2024
Targeting NOX2 with Bivalent Small-Molecule p47phox–p22phox Inhibitors
J Zang, F Peters, Y Cambet, E Cifuentes-Pagano, MMS Hissabu, ...
Journal of Medicinal Chemistry 66 (21), 14963-15005, 2023
2023
Structural determinants of ligand binding to ATP dependent enzymes: Studies of Protein Kinase and Heat Shock Protein 70.
D Narayanan
UiT Norges arktiske universitet, 2017
2017
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Articles 1–12