A comparative assessment study of known small-molecule Keap1− Nrf2 protein–protein interaction inhibitors: chemical synthesis, binding properties, and cellular activity KT Tran, JS Pallesen, SMØ Solbak, D Narayanan, A Baig, J Zang, ... Journal of medicinal chemistry 62 (17), 8028-8052, 2019 | 72 | 2019 |
Targeting the redox landscape in cancer therapy D Narayanan, S Ma, D Özcelik Cancers 12 (7), 1706, 2020 | 35 | 2020 |
Deconstructing noncovalent Kelch-like ECH-associated protein 1 (Keap1) inhibitors into fragments to reconstruct new potent compounds JS Pallesen, D Narayanan, KT Tran, SMØ Solbak, G Marseglia, ... Journal of medicinal chemistry 64 (8), 4623-4661, 2021 | 31 | 2021 |
Developing inhibitors of the p47phox–p22phox protein–protein interaction by fragment-based drug discovery SMØ Solbak, J Zang, D Narayanan, LJ Høj, S Bucciarelli, C Softley, ... Journal of Medicinal Chemistry 63 (3), 1156-1177, 2020 | 27 | 2020 |
Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches OA Gani, B Thakkar, D Narayanan, KA Alam, P Kyomuhendo, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (10), 1605-1616, 2015 | 18 | 2015 |
Development of noncovalent small-molecule Keap1-Nrf2 inhibitors by fragment-based drug discovery D Narayanan, KT Tran, JS Pallesen, SMØ Solbak, Y Qin, E Mukminova, ... Journal of medicinal chemistry 65 (21), 14481-14526, 2022 | 15 | 2022 |
Evaluating the Predictivity of Virtual Screening for A bl Kinase Inhibitors to Hinder Drug Resistance OA Gani, D Narayanan, RA Engh Chemical Biology & Drug Design 82 (5), 506-519, 2013 | 12 | 2013 |
Small-molecule modulators of tumor necrosis factor signaling H Chédotal, D Narayanan, K Povlsen, CH Gotfredsen, R Brambilla, ... Drug discovery today, 103575, 2023 | 7 | 2023 |
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR D Narayanan, OA Gani, FXE Gruber, RA Engh Journal of Cheminformatics 9, 1-19, 2017 | 4 | 2017 |
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking and kinase inhibition D Narayanan, ASG Larsen, SJ Gauger, R Adafia, RB Hammershøi, ... bioRxiv, 2024.03. 26.586665, 2024 | | 2024 |
Targeting NOX2 with Bivalent Small-Molecule p47phox–p22phox Inhibitors J Zang, F Peters, Y Cambet, E Cifuentes-Pagano, MMS Hissabu, ... Journal of Medicinal Chemistry 66 (21), 14963-15005, 2023 | | 2023 |
Structural determinants of ligand binding to ATP dependent enzymes: Studies of Protein Kinase and Heat Shock Protein 70. D Narayanan UiT Norges arktiske universitet, 2017 | | 2017 |