Computational design of ligand-binding proteins with high affinity and selectivity CE Tinberg, SD Khare, J Dou, L Doyle, JW Nelson, A Schena, ... Nature 501 (7466), 212-216, 2013 | 484 | 2013 |
De novo design of a fluorescence-activating β-barrel J Dou, AA Vorobieva, W Sheffler, LA Doyle, H Park, MJ Bick, B Mao, ... Nature 561 (7724), 485-491, 2018 | 320 | 2018 |
Computational design of transmembrane pores C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ... Nature 585 (7823), 129-134, 2020 | 141 | 2020 |
Principles for designing proteins with cavities formed by curved β sheets E Marcos, B Basanta, TM Chidyausiku, Y Tang, G Oberdorfer, G Liu, ... Science 355 (6321), 201-206, 2017 | 134 | 2017 |
CSAR benchmark exercise 2013: evaluation of results from a combined computational protein design, docking, and scoring/ranking challenge RD Smith, KL Damm-Ganamet, JB Dunbar Jr, A Ahmed, K Chinnaswamy, ... Journal of chemical information and modeling 56 (6), 1022-1031, 2016 | 58 | 2016 |
Sampling and energy evaluation challenges in ligand binding protein design J Dou, L Doyle, P Jr Greisen, A Schena, H Park, K Johnsson, BL Stoddard, ... Protein Science 26 (12), 2426-2437, 2017 | 47 | 2017 |
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins JC Klima, LA Doyle, JD Lee, M Rappleye, LA Gagnon, MY Lee, EP Barros, ... Nature communications 12 (1), 856, 2021 | 39 | 2021 |
Improving the efficiency of ligand-binding protein design with molecular dynamics simulations EP Barros, JM Schiffer, A Vorobieva, J Dou, D Baker, RE Amaro Journal of chemical theory and computation 15 (10), 5703-5715, 2019 | 23 | 2019 |
Bacterial expression and protein purification of mini-fluorescence-activating proteins JC Klima, CM Chow, J Dou, AA Vorobieva, L Carter, D Baker | 5 | 2021 |
Parallelized identification of on-and off-target protein interactions J Dou, I Goreshnik, C Bryan, D Baker, EM Strauch Molecular systems design & engineering 5 (1), 349-357, 2020 | 2 | 2020 |
High affinity digoxigenin binding proteins D Baker, CE Tinberg, SD Khare, DOU Jiayi US Patent 9,840,539, 2017 | 1 | 2017 |
Beta barrel polypeptides and methods for their use DOU Jiayi, A Vorobieva, JC Klima, D Baker US Patent App. 17/041,363, 2021 | | 2021 |
HARNESSING BACKBONE STRAIN TO DESIGN BETA-BARREL PROTEINS DE NOVO: FROM FIRST PRINCIPLES TO APPLICATION A Vorobieva, J Dou, W Sheffler, B Mao, M Bick, L Doyle, J Klima, ... PROTEIN SCIENCE 28, 115-116, 2019 | | 2019 |
MD in protein design: Investigation of binding determinants for design strategies and screening EP de Barros, J Schiffer, A Vorobieva, J Dou, D Baker, R Amaro ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Exploring the Molecular Design of Ligand Binding Sites by Computational Protein Design J Dou | | 2017 |
High affinity digoxigenin binding proteins D Baker, CE TINBERG, SD KHARE, DOU Jiayi | | 2014 |
Principles for designing proteins with cavities formed by curved b sheets R Guan, DA Silva, J Dou, JH Pereira, R Xiao, B Sankaran, PH Zwart, ... | | |